Kathy Morelli

Translational Neuroscientist and Bioengineer. Assistant Professor, Dept. of Neurological Sciences, Larner College of Medicine at the University of Vermont.

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

Heartiest congratulations to our postdoc Kathryn Morelli on her new position as Assistant Professor at the Dept of Neurological Sciences at the University of Vermont!!! Please follow @khmorelli for more amazing science!

[Nature Neuroscience @NatureNeuro]

Expressing an RNA-targeting CRISPR–Cas13d system in #Huntington's disease mouse model striatum selectively reduces mutant HTT mRNA and protein, improves motor coordination, and reduces atrophy

New from @yeo_lab @khmorelli @QianWu666666 @duanwen06 et al.

https://t.co/tYetbxtWJL

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

UCSD's press release describing our recent work with Leslie Thompson and Wenzhen Duan in demonstrating the reduction of RNA and protein toxicity in preclinical models of Huntington's diseases. https://t.co/UdDTNP087z

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

Our latest research published with @SpringerNature in @NatureNeuro targeting the expanded CAG repeats in Huntington's IPSC and mouse disease models in collaboration with Leslie Thompson and Wenzhen Duan. Congrats Kathy, Maya and colleagues at my lab.https://t.co/pOt9vonpHj

[Oded Rechavi @OdedRechavi]

Reviewing papers of people who did their post doc with you

[Kathy Morelli @khmorelli]

@elonmusk Then please fix Tesla’s leasing department. I moved and they have refused to send the title to my new state (it’s been 9 months) so now my car which I’m still required to pay for remains unregistered and undriveable……….care about your customers

[Science Translational Medicine @ScienceTM]

Don't miss this week's new issue of Science Translational Medicine! https://t.co/XaZ26Eayer

[Kristopher Brannan @bRaNnAn_LAB]

@khmorelli for the cover! Beautiful work.

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

To identify that loss of RNA binding protein CELF2 leads to dysfunction in the MECP2 pathway. Recognizing that loss of MECP2 is associated with Rett’s syndrome, we explored NMDA antagonists, which are currently in clinical trials for Rett’s, to rescue neuronal dysfunction.

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

Myotonic dystrophy type 1 (DM1) is the most common form of muscular dystrophy but the molecular basis for neurocognitive defects in DM1 patients is unknown. Excited to share our cover work where we generated 3D cortical organoids from DM1 patients.
https://t.co/f5AxFwi4fG

[Gene Yeo’s Lab at UC San Diego @yeo_lab]

First author postdoc @khmorelli and team leveraged single-cell RNA-seq, RNA-targeting CRISPR/Cas13d, enhanced CLIP, multi-electrode arrays and integrative analysis to study her 3D cortical organoids. Congrats Kathy and current and past members in @yeo_lab and John Day at Stanford

[𝘿𝙧. 𝘾𝙧𝙮𝙨𝙩𝙖𝙡 𝙍𝙤𝙜𝙚𝙧𝙨 ≽(◕ ᴗ ◕)≼ 🐥🐸 @RogersLabUCD]

I was thinking about some of the comments I received on my F32 NIH postdoctoral fellowship application from 6-7 years ago. It’s surprising how frustrated I still get when I think about it. A thread... 1/

[Kathy Morelli @khmorelli]

Hey, I am helping a great cause. Check out https://t.co/rs0oxtb9Mh

[DMM Journal @DMM_Journal]

Kathryn Morelli @yeo_lab on building cortical #organoids from #MyotonicDystrophy iPSCs and then cutting out the CUG repeats. #DiseaseModelling #CSGeneandCellTherapy

[Daniel Berky RPh MS דן mindly.social/@Daniel_Berky @DanBerky]

@DavidZodda Back in 2018, when Trump fired the Pandemic Preparedness Task Force, he stated his position clearly: "Public health and safety isn't the governmemnt's job".

[Science Magazine @ScienceMagazine]

In an editorial, @hholdenthorp emphasizes that for science to be best equipped to serve people "on demand” —such as developing a #coronavirus vaccine on a rapid timeline — science must be respected and experts allowed to communicate. https://t.co/vvf41KmY0D

[Muscular Dystrophy Association @MDAorg]

We are excited to share that @Invitae has opened a program offering free #genetic testing and post-test counseling to those suspected of having diseases, including #musculardystrophy, to promote early diagnosis and treatment. Learn more from @md_today: https://t.co/rZmD5JPM2z

[Kathy Morelli @khmorelli]

Wow, what a breakthrough! This is what keeps me motivated during all the long hours working in the lab.

[Muscular Dystrophy Association @MDAorg]

Our national ambassador Faith Fortenberry learned the true meaning of independence when she was able to swim for three hours thanks to the impact of MDA funding that made new treatments possible! https://t.co/f9KGYGbUIp

[Muscular Dystrophy Association @MDAorg]

MG FAMILIES: Researchers @AlexionPharma are looking for children w/ #myastheniagravis to participate in a Phase 3 study to evaluate whether eculizumab leads to increased muscle strength. See details about this #clinicaltrial here: https://t.co/WGXk6N8hUG

[Science Magazine @ScienceMagazine]

A research team has engineered a therapeutic #protein that enhances the #cancer-killing power of #TCells while avoiding healthy tissue damage in mice and a monkey with #ColonCancer. Read the research from @ScienceTM: https://t.co/Ae25cEYn7D