Glover Lab

Developmental biology research group interested in the mechanisms driving embryonic pattern formation. The Roslin Institute.

[Andrew Wood @AndrewWoodLab]

🔬 New lab preprint: How does the mode of oncogene activation shape PROTAC efficacy?

Led by Evelina Gudauskaite, we ask whether stabilising mutations vs transcriptional upregulation have distinct consequences for targeted protein degradation.

https://t.co/vH8Dcud4yg.

[Andrew Wood @AndrewWoodLab]

Today in @NatureGenet, we report a saturation genome editing study that systematically dissects the degron of β-Catenin: one of the most frequently mutated regions of the cancer genome. Collab with @kiddevonline and @DeryaDOzdemir, among many others

https://t.co/ZWiRwpwgpH

[Rory Cooper @rorylcooper]

🚨 Come join us @sheffielduni for a PhD on the evolution and development of feathers and flight! 🐣🔬

This project is supervised by @Mattowers1 @AlexGFletcher, and I'm excited to be involved as a project advisor. Please share!

https://t.co/NHZLR3hXG6

[Glover Lab @lab_glover]

🚨 Introducing FuChi (Fucci Chicken), the first avian cell cycle reporter line. Thank you to all those who made this paper possible. I believe it really showcases the power and beauty of the chick embryo as a developmental biology model. 🐥 🥚 🔬

https://t.co/wgs7wTQyY3

[Elly.Gaunt_lab 💙 @GauntLab]

Phewww it was some journey getting to preprint but finally here we are! Awesome fun collaboration with *ten* @roslininstitute labs represented and wider collabs too, showing that diverse IAVs can replicate in cow udders, with biggest credit to @RuteMPinto
https://t.co/77Y2nY4PG5

[Society for Developmental Biology @SocDevBio]

🐣Chick embryo (Gallus gallus domesticus): a window into vertebrate development. From heart and limb formation to neural crest migration and axis patterning, this model has been cracking the developmental code for over a century. Image by Vincent Pasque #ModelMonday #DevBio

[Ruth Williams @Ruth_Y_Williams]

The 12th Avian Model Systems Meeting is happening this fall!! https://t.co/RlrCF1oTwX We hope you can join us at the Stowers Institute @ScienceStowers, Kansas City to talk all things birds, biology and breakthroughs!! 🐣🐔🪶

[Anestis Tsakiridis @a_tsakiridis]

Only a few days left to apply for our @BBSRCWhiteRose-funded PhD project with
@ChrisToseland aiming to understand how biomechanical cues crosstalk with extrinsic signals to influence cell fate decisions during hESC/NMP differentiation. Please RT!
https://t.co/nEFfAbRdo1

[Elly.Gaunt_lab 💙 @GauntLab]

My lab is advertising just one PhD studentship this year, looking at consequences of maternally acquired viral infection for foetus with @dr_sara_c , @neilmabbott1 and @lab_glover . Please see link below for further info!

https://t.co/Hf9Bu30Ftv

[Glover Lab @lab_glover]

@Analia_hr @xiongfz Congratulations, Ana! Well deserved.

[Ruth Williams @Ruth_Y_Williams]

The postdoc position in my lab @FBMH_UoM is open for applications until 15th November https://t.co/41X4A6oRIY and I am also looking for a research technician https://t.co/50eKglMJ2D! Come and have fun with Chicken embryos and single-cell Multiomics! 🐣🧬🐣

[Pavel Tomancak @PavelTomancak]

Great story from @AnaisBailles on the role of #mechanics in initiating the remarkable #Hydra reformation from #singlecells to functional #animal. Supported by @GiuliaSerafin12 HCR, @carldmodes & @zechnerlab modeling & Heino Andreas Hydra husbandry @mpicbg @csbdresden @PoLDresden

[Hiscock Lab @hiscock_lab]

🚨 Job alert in theory/devbio/mathbio 🚨Official applications for PhD/postdoc opportunities in the Hiscock lab are now live! Check out https://t.co/iq245oMe9H for links. Deadline 10 November.

[Ruth Williams @Ruth_Y_Williams]

Come and join the Williams lab @OfficialUoM @FBMH_UoM @The_MRC We are using single-cell Multiomics and in vivo CRISPR approaches to understand the molecular mechanisms underlying lineage segregation from the neural plate border 🐣https://t.co/41X4A6oRIY

[PLOS Biology @PLOSBiology]

#CHARGEsyndrome involves aberrant #NeuralCrest development due to mutations in CHD7. @Ruth_Y_Williams @saukaspengler &co explore enhancers & tissue-specific TFs that regulate Chd7 expression in developing chick & human neural crest @TSS_Lab #PLOSBiology https://t.co/ADyVLyeqEv

[Ruth Williams @Ruth_Y_Williams]

We are looking for an enthusiastic PhD candidate to study the regulation of chromatin remodellers in neural crest and their role in developmental disorders.
#neuralcrest #neurocristopathies #singlecell #multiome #CRISPR
@smbanka @OfficialUoM @The_MRC https://t.co/JhqsfVMBl1

[Harry McNamara @h4rrymcnamara]

Our study decoding gastruloid symmetry breaking is now live @NatureCellBio!

https://t.co/rRWRy853Yq

Thank you to the NCB edititorial team and to our reviewers for a constructive review process which helped improve our study. A thread on updates (1/n):

[The Milinkovitch-Tzika lab @LANEVOL]

Grigorii & Michel’s method for staining collagen fibres (https://t.co/3rVx86U4cA) has generated multiple award-winning images. Now, we’ve won 3rd prize in @MicroscopyToday’s Published Image category & 1st prize in their Video category!🔬🐁
@UNIGEnews @genevunige @Biologie_UNIGE

[Hiscock Lab @hiscock_lab]

🚨 Job alert in theory/devbio🚨 Funded by an ERC Starting Grant (woohoo!!), we are recruiting theory postdocs and PhD students to study how embryonic patterns self-organize. Please RT 😊 @ERC_Research @TLM_Cambridge @the_Node @SMB_MathBiology @PhysicsofLifeUK @PoLDresden 1/🧵