Becky Lamason

Associate professor at MIT studying host-pathogen interactions

[Becky Lamason @lamasonlab]

Excited to share our latest work from first author @PatrickWoida. Using a novel surface display platform for expression of split TurboID, we discovered that CYLD is recruited to the Listeria surface via the effector InlC and that it supports cell-to-cell spread

[bioRxiv Microbiology @biorxiv_micrbio]

Proximity labeling of the Listeria monocytogenes surface reveals pathogen control of a host deubiquitinase https://t.co/lYt2PCfwgl #biorxiv_micrbio

[Becky Lamason @lamasonlab]

Check out our latest paper from first author Allison Scott using a powerful enrichment strategy to enable transcriptional profiling of the early stages of a rickettsial infection

[bioRxiv Microbiology @biorxiv_micrbio]

Hybrid capture RNA-seq defines temporal gene expression in Rickettsia https://t.co/GWintq7OUO #biorxiv_micrbio

[Becky Lamason @lamasonlab]

Thrilled to share our latest story from postdoc @sit_brandon! Using a functional genetic screen, he discovered an unexpected way that Rickettsia relies on the host to stabilize the Sca2 surface protein that drives pathogen motility and virulence.

[bioRxiv Microbiology @biorxiv_micrbio]

Host cyclophilin-mediated maturation of an obligate intracellular bacterial surface virulence factor https://t.co/6O6Z8c7SIv #biorxiv_micrbio

[Journal of Cell Biology @JCellBiol]

Cytosolic companionship: Rickettsia connects with the endoplasmic reticulum. Stacey Gilk (@sdgilk) @UNMCCOM discusses new study from Acevedo-Sánchez et al. @lamasonlab (https://t.co/8e5ocViEjR) rin Spotlight: https://t.co/CNU3OOELZd
#Microbiology #ER_literature

[Becky Lamason @lamasonlab]

Thanks @LillianWEden for the excellent write-up about our work!

[MIT Biology @MITBiology]

Studying the pathogen R. parkeri, researchers in the Lamason Lab discovered the first evidence of extensive and stable interkingdom contacts between a pathogen and a eukaryotic organelle @JCellBiol https://t.co/2FCihP09Um

[Becky Lamason @lamasonlab]

We are excited to kick off the new year with a new publication from the lab!

[Journal of Cell Biology @JCellBiol]

Acevedo-Sánchez et al. @lamasonlab @MITBiology characterize a novel interkingdom contact site between the ER and a cytosolic bacterial pathogen. They report that these bacteria–ER contacts (BERCs) require the tethering proteins VAPA and VAPB. https://t.co/m2GQUJNXRx
#Microbiology

[Becky Lamason @lamasonlab]

@lradoshevich26 @GeiselBiofilm @ASMicrobiology @JBacteriology Thanks!

[George O'Toole (he/him/his) @GeiselBiofilm]

Editor's Pick: Advancing new models is often tied to technical advances. Lamason et al. add to the toolkit for studying Rickettsia parkeri with new expression and gene silencing approaches. @ASMicrobiology @JBacteriology
https://t.co/IyEaxqTzL1

[Becky Lamason @lamasonlab]

Great job Dr. Vondrak on a beautifully defended thesis!

[MIT Biology @MITBiology]

The enemy within: new research from the
@lamasonlab reveals insights into the arsenal Rickettsia parkeri uses against its host. https://t.co/g68D1Hwiad

[Becky Lamason @lamasonlab]

More publication alerts from the lab! The final version (+ some new data) of our paper using BONCAT to identify novel Rickettsia parkeri secreted effectors is out @NatureComms. https://t.co/ygea5EiGLq

[Becky Lamason @lamasonlab]

Thrilled to share our latest preprint! Most of the Rickettsia secretome is a mystery, and 1st author Allen Sanderlin pioneered the use of BONCAT in this obligate intracellular pathogen to solve this problem, uncovering many new effectors largely unique to this pathogen.

[Becky Lamason @lamasonlab]

Amazing job by @HannahKurkaMarg! She gave a stellar talk at the ASR 2024 annual meeting today.

[Bryson Lab @TheBrysonLab]

Ever wonder how to engineer Mtb to deliver heterologous cargo to the phagosome? Look no further!!! After trying many strategies over 6 years, we figured out a strategy. (1/10)

[Becky Lamason @lamasonlab]

New preprint is out detailing the discovery of a novel interaction between Sca4 and clathrin. Great work from authors Cassandra and Brandon @sit_brandon and our collaborators Nam and Kevin from the Macaluso lab!

[bioRxiv Microbiology @biorxiv_micrbio]

A conserved interaction between the effector Sca4 and host endocytic machinery suggests additional roles for Sca4 during rickettsial ... https://t.co/u9dFlenHAm #biorxiv_micrbio

[Becky Lamason @lamasonlab]

The final version of our paper pioneering the use of inducible expression and CRISPRi tools for rickettsia is online @JBacteriology! Thanks to the reviewers and editor for their helpful feedback and effort.
https://t.co/lWNeQzUYE8

[Becky Lamason @lamasonlab]

Thrilled to share our preprint on inducible expression and CRISPRi tools for Rickettsia from authors @jontmcginn, Annie Wen, @dbrinkley97, and Desmond Edwards! https://t.co/D3p2fqwgN5

[Becky Lamason @lamasonlab]

Congrats to postdoc @PatrickWoida on a wonderful talk at BBM2024 exploring the host proteins interacting with Listeria!

[Becky Lamason @lamasonlab]

Congrats to Yami Acevedo-Sánchez on her phenomenal defense! She presented a great story and even showed some surprise new data for the audience. Way to go!!

[Becky Lamason @lamasonlab]

@goleylab @MattWelchLab Congrats @MattWelchLab!!

[Becky Lamason @lamasonlab]

Thrilled to share our preprint on inducible expression and CRISPRi tools for Rickettsia from authors @jontmcginn, Annie Wen, @dbrinkley97, and Desmond Edwards! https://t.co/D3p2fqwgN5