Now online at @ScienceMagazine: 1st immune correlates paper emanating from the US Govβt/COVID-19 Prevention Network (CoVPN) Biostatistics Team (& others!); ππ«. πππππ« ππ’π₯πππ«π et al.βs analysis of the mRNA-1273 vaccine efficacy trial. https://t.co/V08QTdeRC2 π§΅ (1/5)
β¨New work from USG/CoVPN biostats teamβ¨:
Fong et al.'s immune correlates analysis of the ENSEMBLE single Ad26.COV2.S dose vaccine efficacy clinical trial now out in @NatureMicrobiol
https://t.co/V5uXeor6P1
New work from the US Govβt/CoVPN Biostats Team (& others): Fong et al. immune correlates analysis of a single Ad26.COV2.S dose in the ENSEMBLE vaccine efficacy trial, on medRxiv: https://t.co/RAXcqs2WAN π§΅ 1/7
Another key finding: This comparison supports consistency in the ID50 nAb titer level needed for the same level of efficacy across mRNA and adenovirus-vectored vaccine platforms: potentially a transportable surrogate endpoint across vaccine platforms π§΅ 6/7