B.S. from Penn State, and Ph.D. in chemistry from UW-Madison (Gellman lab). Currently a postdoc fellow at Harvard Medical School & Boston Children’s Hospital.
Our work assessing the effect of preorganization on dihydrazide activity is out in @J_A_C_S. We find that dihydrazides with simple flexible tethers can replicate much of the catalytic activity of complex dihydrazides with preorganized foldamer scaffolds.
https://t.co/XS6FcYmGiq
Our work on bifunctional organocatalysis of aldol reactions by flexible dihydrazides is out in @J_A_C_S. We find that hydrazide units connected by long, flexible linkers offer significant rate enhancement relative to monohydrazides. https://t.co/3djMkuzMx5
Dear Destined Ones, the new year has indeed brought us new joys to celebrate!
In the 2024 Steam Awards, which saw participation from over 40 million players, #BlackMythWukong was honored with three awards, including Game of the Year:
• Game of the Year
• Best Game You Suck At
• Outstanding Story-Rich Game
We would like to express our gratitude to every player who voted for us; your support has added extra warmth to the start of 2025. We also extend our congratulations to all the other nominated and winning games; it is an honor to have contributed, alongside you, to the rich tapestry of immersive moments and unforgettable memories for the vast Steam community.
Lastly, to all Destined Ones, may the new year find you playing hard and resting well!
Today we report in @NatureBiotech "An adenine base editor variant expands context compatibility". Existing ABEs function most effectively on TA. Here we develop TadA8r, a new TadA variant that extends potent deoxyadenosine deamination to GA and AA. 1/n https://t.co/gvP0nNuRWC
You have applied for a #PhD / #postdoc position, but the professor doesn't reply to you. Why?
As I often see students asking this question, I can try to explain this phenomenon (which is obvious to any faculty).
#phdlife#AcademicChatter
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.