Lei Liu

B.S. from Penn State, and Ph.D. in chemistry from UW-Madison (Gellman lab). Currently a postdoc fellow at Harvard Medical School & Boston Children’s Hospital.

[Gellman Lab @bondamidebond]

Our work assessing the effect of preorganization on dihydrazide activity is out in @J_A_C_S. We find that dihydrazides with simple flexible tethers can replicate much of the catalytic activity of complex dihydrazides with preorganized foldamer scaffolds.
https://t.co/XS6FcYmGiq

[Lei Liu @liulei5183]

@GJX__ Sekiro is the very first Souls game I played. It’s difficult but also incredibly rewarding.

[Lei Liu @liulei5183]

@bondamidebond @J_A_C_S Congratulations to Philip and Sam!

[Gellman Lab @bondamidebond]

Our work on bifunctional organocatalysis of aldol reactions by flexible dihydrazides is out in @J_A_C_S. We find that hydrazide units connected by long, flexible linkers offer significant rate enhancement relative to monohydrazides. https://t.co/3djMkuzMx5

[Black Myth @BlackMythGame]

Dear Destined Ones, the new year has indeed brought us new joys to celebrate!

In the 2024 Steam Awards, which saw participation from over 40 million players, #BlackMythWukong was honored with three awards, including Game of the Year:

• Game of the Year
• Best Game You Suck At
• Outstanding Story-Rich Game

We would like to express our gratitude to every player who voted for us; your support has added extra warmth to the start of 2025. We also extend our congratulations to all the other nominated and winning games; it is an honor to have contributed, alongside you, to the rich tapestry of immersive moments and unforgettable memories for the vast Steam community.

Lastly, to all Destined Ones, may the new year find you playing hard and resting well!

[Lei Liu @liulei5183]

@MWAMofficial Remember me, Smells like teen spirit, and Merry-go-round

[PHD Comics @PHDcomics]

Proof

[Lei Liu @liulei5183]

@BlackMythGame 无冕之王！

[Lei Liu @liulei5183]

@K_A_S_E_N_G @thegameawards @PlayStation @TeamAsobi Sony sponsored TGA for sure

[Lei Liu @liulei5183]

@MacMillan_Lab @HuthSean @JacobGeri1 @JamesO760 Congratulations, @HuthSean !

[Lei Liu @liulei5183]

@EdwardBPimentel @HTSohLab Congratulations, Edward! Best of luck with your new science 🧬

[Lei Liu @liulei5183]

@Scott_LabUM @Sanford_Lab @JOC_OL @gregdbowden @jays_wright @brianpcary

[Lei Liu @liulei5183]

@DSRoberts007 @CarolynBertozzi @yingge2121 @SongJin_Chem Congratulations, David! Well deserved

[Lei Liu @liulei5183]

@brianpcary

[WARF (Wisconsin Alumni Research Foundation) @WARF_News]

A synthetic peptide developed by Samuel Gellman, Kyle Brown and Rylie Morris could lead to a powerful new drug to treat type 2 diabetes and obesity. @bondamidebond @UWMadisonChem @UWMadisonLS #WisconsinInnovates https://t.co/O7pCYoKex6

[Lei Liu @liulei5183]

@MWAMofficial Fly again & Smells like teen spirit

[Lei Liu @liulei5183]

@MWAMofficial The MWAM concert in Chicago was incredible! Also, MWAM was my most streamed artist in 2023 on YouTube music (I don’t use Spotify).

[Weixin Tang @WeixinT]

Today we report in @NatureBiotech "An adenine base editor variant expands context compatibility". Existing ABEs function most effectively on TA. Here we develop TadA8r, a new TadA variant that extends potent deoxyadenosine deamination to GA and AA. 1/n https://t.co/gvP0nNuRWC

[Andrew Akbashev @Andrew_Akbashev]

You have applied for a #PhD / #postdoc position, but the professor doesn't reply to you. Why?

As I often see students asking this question, I can try to explain this phenomenon (which is obvious to any faculty).

#phdlife #AcademicChatter

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.

[Gellman Lab @bondamidebond]

Check out our lab's newest publication on the impact of backbone modification on PTH (1-34)'s signaling profile!