Loges Krshnan

Molecular cell biologist, studying how proteins are maintained in cells. Now @mrcppu, previously @unimelb @NTU_LKCmedicine @UniofOxford. 🇲🇾🌈👨🏾‍🔬🌏

[Loges Krshnan @LogesK]

Our preprint has now been peer-reviewed and published! We described a role for kinase CK2 and phosphatase CTDNEP1 in regulating protein turnover of SUN2, an inner nuclear membrane protein. Exciting new research avenues for nuclear envelopathies.
https://t.co/xZslMM0xZx

[Loges Krshnan @LogesK]

Really exciting study! We also didn’t find any membrane protein components for extraction of the nuclear envelope protein SUN2 (ubiquitylated by SCF E3). We discussed that this could be due to redundancy or that pulling force by p97 alone is sufficient.

https://t.co/Z6xfr0SuXH

[James Olzmann @OlzmannLab]

1/ New preprint out! We show that PROTAC-induced ubiquitination can bypass canonical ERAD to degrade ER membrane proteins. Wonderful collaboration w/ @DanNomura and huge credit to grad student superstar Sydney Tomlinson!
https://t.co/CT5knDfjSM

[biorxiv_biochem @biorxiv_biochem]

The EF-hand domain of MINDY3 is a Ubiquitin and RAD23 UBL-binding domain https://t.co/ZYTQE38Hfl #biorxiv_biochem

[Portland Press @PPPublishing]

Branched ubiquitin chains significantly expand the ubiquitin system's signalling capacity. In this #BiochemSocTrans review, McFarland et al. discuss the emerging tools and methods for studying the roles of branched chains in diverse cellular processes.https://t.co/eRo8Mfhi9I

[Loges Krshnan @LogesK]

@NickoSunway123 @Marius_Lemberg @donem_avci @RobinCorey1 @MichaelvdWeijer @Dunn_School Congratulations, Nik!!!

[jobRxiv @jobRxiv]

Postdoc in Biochemistry and Cell Biology of SUMOylation and Nucleosome @MSuskiewicz

Postdoctoral Position in Biochemistry and Cell Biology of SUMOylation and Nucleosome

https://t.co/oW610exGeL

#biochemistry #chromatin_biology #nucleosome #structural_...
https://t.co/oW610exGeL

[Loges Krshnan @LogesK]

@joanaverissimof @HelmholtzMunich @NatalieKrahmer Good luck!!! I am sure you will do amazingly. We need to do a reunion in somewhere in Europe.

[Loges Krshnan @LogesK]

@DrNatSampaio 😂 I envy you though. I wish I know how to code. I didn’t learn this early in my scientific journey, but trying to learn it now.

[Marcin J. Suskiewicz @MSuskiewicz]

Our team in Orléans (France) is looking for a new postdoc, to work closely with a research associate, Ibtissam Talhaoui, on a project focused on potential SUMO E3 ligases targeting the nucleosome. The details here: https://t.co/CM3poCelab

[Loges Krshnan @LogesK]

@MichaelvdWeijer @NickoSunway123 @LuLin_Jiang @TrostLab Congrats @MichaelvdWeijer!!!

[Loges Krshnan @LogesK]

@NickoSunway123 @MichaelvdWeijer @Dunn_School Congratulations @NickoSunway123 and @MichaelvdWeijer!!!

[Loges Krshnan @LogesK]

Busy at work. *sigh* I need a holiday. #EMBOubiquitin2024 #hardtimes #difficultworklife #cavtat #dundee #ubiquitin #scientist @dpriesm @RaRodea16 @gallant_kai

[Loges Krshnan @LogesK]

@MSuskiewicz I hope to catch up with you at the #EMBOubiquitin2024!!!It is my first time attending EMBO Ub&Ubl meeting.

[Rachel O Dea @RaRodea16]

Delighted to say I have been awarded a MSCA/UKRI funded postdoctoral fellowship to investigate UFMylation at specific sites with
@YKulathu
. Looking forward to having a new favourite UBL.
@MSCActions
@UKRI_News @mrcppu

[Elliott Lab @Elliott_Lab_Ox]

We are hiring! Two structural biology/biochemistry postdoc positions are available in our lab - come and join a lively Team in the thriving city of Oxford! Deadline 4th October 2024. Further details are here: https://t.co/fAMkerIP9W

[Loges Krshnan @LogesK]

@LachlanDeimel @UniofOxford Congratulations Lachlan!!! Wish you the best in your current postdoc! 🎉👏

[Martin Smith @martinrsmith]

UK expensive visas - latest evidence:

- Cancer Research UK is expecting to spend £700k on visa costs each year - the equivalent cost of 17 new CRUK PhD students

- Cambridge cancer institute being outcompeted for specialists by institutes in Germany, due to costs

[Cancer Research UK Policy @CRUK_Policy]

Today we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growthToday we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growthToday we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growthToday we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growthToday we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growthToday we are publishing evidence from our Institutes to show the impact of changes to the UK immigration system on cancer research.

We call on the new UK Government to reduce costs and review the system so it works for research - to meet their ambitions for health and growth.

[Hofmann_Lab @LabHofmann]

After a long time in the making, our study on bacterial clippases is finally available as a preprint https://t.co/wVyqGbJaC7
These are really fascinating enzymes, for which there will be a ton of applications in studying the #ubiquitin system

[Malte Gersch @MalteGersch]

For all ubiquitin, deubiquitinase and chemical biology aficionados:
Here's a preprint from the lab introducing 2 new active DUBs in humans & a unique type of DUB activity one would miss with the widely used panels of free ubiquitin chains.
https://t.co/ji1Z8jBNSg
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