Sarah Lutz

Neuroimmunology lab @UICCOM. Unlocking the mystery of the blood-brain barrier. studying #covid_19 and #MSResearch #neuroscience #uic #uiccom

[Sarah Lutz @lutzlab]

What causes #brainfog in #COVID_19? Our new study @Brain1878 shows that mild SARS-CoV-2 infection suppresses #cerebrovascular Wnt/beta-catenin activity, opening the #blood_brain_barrier. BBB-targeted Wnt ligands mitigate cognitive impairment in mice. A brief tweetorial!

[Sarah Lutz @lutzlab]

Thanks for the recognition, @vascularbiology ! I’m so proud of our team for this work ❤️

[NAVBO @vascularbiology]

#NAVBO Member Publication Alert

Engineered Wnt7a ligands rescue blood–brain barrier and cognitive deficits in a COVID-19 mouse model

Dr. Sarah Lutz lab @Brain1878 2024 @jalees_rehman @lutzlab
https://t.co/B6J9bLqXps

[Sarah Lutz @lutzlab]

Congratulations to Dr. Trevino, my first PhD student, on his degree. Commencement ceremony was a blast!

[Sarah Lutz @lutzlab]

@danielsaloreich Congratulations, Danny!

[Craig E Brown @CraigEdBrown]

Blood borne #cytokines like #IL-10 are often elevated in chronic conditions associated with cognitive impairment (eg. #longCOVID). Protective or pathogenic? Here’s ⁦@sharmasorabh88⁩ unexpected findings in a mouse model of #diabetes. https://t.co/QVxUPjrxNx

[John Lukens @LukensJohnR]

Brain endothelial GSDMD activation mediates inflammatory blood-brain barrier breakdown
https://t.co/xayXAsobkc. @Nature

[Sarah Lutz @lutzlab]

@LabHaynes @geronsociety @UconnAging I can’t wait to read it!

[Sarah Lutz @lutzlab]

@Rishi_CUIMC @DAgalliu @AgalliuLab Congratulations @Rishi_CUIMC and @DAgalliu !

[Dritan Agalliu @DAgalliu]

The beautiful work of @Rishi_CUIMC was published in @NeuroCellPress today. Here we show that glutamatergic neuronal activity drives retinal deep plexus angiogenesis and blood-retina barrier maturation.
https://t.co/Mcoo32zQ5b

[Sarah Lutz @lutzlab]

@LabHaynes Wait, what??? How far from campus do you live?

[Sarah Lutz @lutzlab]

@EricTopol Eric, I hope you like this study!

[Sarah Lutz @lutzlab]

What causes #brainfog in #COVID_19? Our new study @Brain1878 shows that mild SARS-CoV-2 infection suppresses #cerebrovascular Wnt/beta-catenin activity, opening the #blood_brain_barrier. BBB-targeted Wnt ligands mitigate cognitive impairment in mice. A brief tweetorial!

[Sarah Lutz @lutzlab]

@Geraghty_Joe @Brain1878 @LabRichner @jalees_rehman @Sanbomics Thanks, Joe!

[Sarah Lutz @lutzlab]

@DAgalliu @Brain1878 @LabRichner @jalees_rehman @Sanbomics Thanks Dritan!!

[Sarah Lutz @lutzlab]

@mattcampbelltcd

[Sarah Lutz @lutzlab]

this work complements important recent studies by others establishing a link between BBB permeability and brainfog in patients with COVID-19 and #LongCovid

[Sarah Lutz @lutzlab]

And suggests that targeting the BBB could offer hope to improve neurological outcomes of COVID-19 https://t.co/QFKUZIyNcY