📢 SAVE THE DATE! RHUMATOPEDIES 2024 is coming
📅Wednesday 4th December 2024
📌 University of Lyon, 69007 LYON
👨⚕️ Lecture by Prof. Daniel Kastner, MD, PhD
📝 Registration: https://t.co/NsfqFNuTfn
📰 Scientific Programme below
6 novel monoallelic PTPN2 mutations in pediatric lupus and Evans syndrome that cause T cell hyperproliferation and high inflammatory cytokines @JExpMed
https://t.co/ODOu1XBd80 @MACattackLab comment
https://t.co/YCuJo3GdY1
@AlexandreBelot @FRLab1 #Mathieu
Very proud to share my first paper on my thesis project, a great collaborative effort between @CIRI_Lyon and @InstitutImagine, now published in @JExpMed. Check it out!
Honored to have been part of this beautiful collaboration with @JEANPIERRMarie from @FRLab1 team in @InstitutImagine for my very first steps in the lab, thanks to @lyacts, @MaudTusseau@AlexandreBelot and Anne-Laure Mathieu ! ✨´
Jeanpierre, Cognard, @FRLab1, @AlexandreBelot, Mathieu @CIRI_Lyon et al. performed exome sequencing in pediatric systemic #lupus and Evans syndrome and identified six novel monoallelic PTPN2 mutations, impairing its regulatory function. https://t.co/O0FZoTSok7
#autoimmunity
Ce 29 février, c'est le #RareDiseaseDay2024.
Au CIRI, les équipes I2BA (T. Henry) et LYACTS (T. Walzer) étudient des maladies rares auto-immunes et auto-inflammatoires.
Un grand merci aux cliniciens qui font avancer la recherche, et aux patient/es !
❔Quel est le lien entre cancer et système immunitaire ?
Thierry Walzer, directeur de recherche @Inserm et chef de l'équipe @lyacts, l'explique dans l'émission #TêtesChercheuses, dont voici un extrait 👇
Retrouvez l'émission complète ici ➡ https://t.co/sjxD0wRHqI
🔬 🌐 Check out our comment on drug development in ultra-rare diseases in @TheLancet, spotlighting promising results of a new C5 inhibitor via SC route for CD55 deficiency. 🩺 #RareDiseases#MedicalBreakthrough"https://t.co/sMr1r4fuEU ⤵️
Fascinating paper on pre-covid possible MIS-C with implications for understanding pathogenesis. Congrats Alex Belot and team. Pre–Covid-19, SARS-CoV-2–Negative Multisystem Inflammatory Syndrome in Children | NEJM https://t.co/oUydODNpuy
Fantastic research day at Rhumatopedies 2023, the 10th edition that welcome in Lyon many talented young researchers in the field of Pediatric Immunology/rheumatology & Incredible talk of our guest @BrodinPetter! Thanks for coming
Sometimes groundbreaking research means demonstrating there nothing new but we missed it before! 'Old' Coronaviruses were triggering MIS-C in children before #SARSCoV2 👇👇👇
#pandemicpreparedness
MIS-C existed pre-COVID? See this report from @AlexandreBelot and colleagues. Time to re-think about Kawasaki disease and other post-infectious inflammatory conditions.
A study suggests that prepandemic and SARS-CoV-2–negative cases that are indistinguishable from MIS-C are characterized by Vβ21.3+ T-cell expansion and may be triggered by other pathogens. Read the full correspondence: https://t.co/vC1T9z1a4n
Thrilled to share our paper in @NEJM on pre-COVID and SARS-CoV-2 negative MIS-C. This condition predates the pandemic but was incredibly rare and often misdiagnosed as Kawasaki Disease Shock Syndrome or Toxic Shock Syndrome without identified bacteria https://t.co/ADSsYrVazj 🧵