Marija Simjanoska

Biochemistry @Columbia

[Sukjin Steve Jang @sukjin_jang]

Excited to share our updated preprint on moth pheromone reception!
Can we leverage structure-based pharmacology to disrupt insect olfactory behavior?
We designed small molecule inhibitors that hijack moth pheromone receptors to block mate recognition. A thread:

[Fitzpatrick Laboratory @FitzpatrickLab]

Over 20 years ago, Zuker et al. discovered the mammalian sweet taste receptors

Now, an exciting collaboration between our labs @ColumbiaBiochem reveals the #cryoEM structure of the human sweet receptor-key to sweet taste perception-online @CellCellPress!

https://t.co/o6AQqpmuJo

[Marija Simjanoska @m_simjanoska]

@FitzpatrickLab @ColumbiaBiochem @LabStahlberg @EPFL @Columbia @harvardmed @BBS_Harvard Could not be more grateful for the past 3 years with the best mentor a student can only hope for. Thank you for everything, Professor. I hope to make you — and everyone who supported and guided me along the way — proud.

[Fitzpatrick Laboratory @FitzpatrickLab]

Many congratulations to @m_simjanoska who found time to make contributions to multiple papers from @FitzpatrickLab @ColumbiaBiochem, spent a Summer in @LabStahlberg @EPFL, has now graduated from @Columbia and is off to @harvardmed for graduate school in the @BBS_Harvard program.

[Fitzpatrick Laboratory @FitzpatrickLab]

Many thanks @rita_strack @naturemethods for highlighting @DuXDaniel @FitzpatrickLab #ultrafast #LaserPhasePlate for #cryoET @CellRepMethods:
https://t.co/GZyLkN1QGx
https://t.co/Ip5Mo3zzIE
#femtosecond #laser #cryoEM experiments made possible by generous support from @cziscience!

[Fitzpatrick Laboratory @FitzpatrickLab]

@DuXDaniel @m_simjanoska @FitzpatrickLab @ZuckermanBrain @ColumbiaBiochem discuss the feasibility of resolving #proteindynamics in processes ranging from #optogenetics to #photosynthesis using a combination of #microED and #UltrafastElectronMicroscopy:

https://t.co/TfiG4nfqxn

[Fitzpatrick Laboratory @FitzpatrickLab]

Excited to share the structural basis of pH-activated #endocytosis by LRP2 using #cryoem now online @CellCellPress:

https://t.co/jue7HiHKx3

Great collaboration with Andrew Beenken @theGABcerutti Jonathan Barasch @ColumbiaKidney @lawrenceshapiro @ZuckermanBrain @ColumbiaBiochem

[Fitzpatrick Laboratory @FitzpatrickLab]

Excited to share the latest #preprint from @FitzpatrickLab on the design of an #ultrafast pulsed laser phase plate for contrast enhancement in #cryoEM and #cryoET by @DuXDaniel:

https://t.co/cPm7DtKi1v

Experiments are now underway with support from @cziscience #visualproteomics

[Cell @CellCellPress]

Now online! Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases https://t.co/8jHmg1KmXv

[Columbia University @Columbia]

A protein normally involved in clearing cells of molecular debris can clump into fibrils, potentially hobbling cells, says a new study by @ZuckermanBrain's @FitpatrickLab. @CellCellPress https://t.co/FLg0bOORj6

[Tamta Arakhamia @tamtaarakhamia]

Mentorship, leadership, innovation - these comprise media crucial to nurturing scientific minds of the future. In my 4yrs @FitzpatrickLab , there was no shortage of it. The brightest young scientists are given opportunities to thrive here, and that’s more important now than ever!

[Columbia University's Zuckerman Institute @ZuckermanBrain]

A new study by our very own @FitpatrickLab uncovers a promising lead into what might be happening inside brain cells for several neurodegenerative diseases.

Read more about the discovery published today in @cellcellpress:

https://t.co/hWkXU0yvK5

[Fitzpatrick Laboratory @FitzpatrickLab]

Many congratulations to our three undergraduate co-first authors @andrewnchang @m_simjanoska @tamtaarakhamia @CC_Columbia @allhailkylin @StanfordBiosci @JingWang0610 @carolynlinlee on the latest paper from @FitzpatrickLab, online now @CellCellPress!

See: https://t.co/A6MOhE2qKI