Rheumatologist. Kaplan MacLean Rheumatology. Providing comprehensive, compassionate care. Helping you turn a new leaf. DMs not answered. T: 760.753.7374
I have been insisting to my patients for years that inflammation in their bodies is riskier than a targeted, intelligently selected drug regimen. This is more important work.
Risk of CV events in RA - cohort study with almost 19K patients
https://t.co/T3Lb7BN5ez
⬇️risk of MI with TNFi and Abatacept
⬇️CV risk with MTX - higher dose better
⬆️risk with GC
great work by @UNMC_Rheum@Dr_K
The number of people dying from the coronavirus across the U.S. is rising again for the first time since April — the reopening and relaxing of social distancing restrictions in some states may be contributing to the trend.
https://t.co/SWCKpf3pew
WHO, NIH, and RECOVERY all ended their HCQ trials in May or June due to lack of efficacy. Touting HCQ as a miracle drug back in April was misguided but understandable. Now it’s July, and we know better. Trust data, not opinions. Read more in our new review https://t.co/e3Mz6w1WQb
Getting a dx of RA can be scary enough for pts, but half have also had a major stressor in the 1y prior (vs 20% in overall pop).
Not only that, these pts experience worse symptoms.
We can do so much by treating the whole patient.
@earlyarthritis OP0263-HPR #EULAR2020@RheumNow
“All pt's with severe #COVID19 should be screened for hyperinflammation (increasing ferritin, decreasing platelets, or ESR) and the HScore to identify the subgroup of patients for whom immunosuppression could improve mortality." #covid4MDs@ACRheum https://t.co/ULJ7PJJy4x
We got concerned. Then we got together. The Covid 19 Global Rheumatology Alliance initiative, conceived two weeks ago from rheumatologists around the world, is now live! Happy to do my part. #rheumresponse@ACRheum@CRASCRRheum
Huge thank you to everyone who has submitted cases in just the first few days.
So far, we have *46 cases* reported, and we just added the EULAR registry today.
We expect the first scientific report to the community to come out early next week.
https://t.co/c4QpUJ2Ufu
Raoult PRE-print: 79 pts w/COVID improve, also receive HCQ
1. Not peer rvwd
2. No control group
3. Incl pts from prior study
4. Migratory/weak endpts
5. Healthy group: 41% only URI & 5% asymptomatic!?!
Not confirmatory; not progress. Need. RCTs.
PDF: https://t.co/Mbrq7bFHk0