Ph.D. in Information Science and Technology. Immuno-oncology, Precision medicine, Translational science, Single cell,Biomarker,Bioinformatics.Tweets my own.
Only few days to #ASCO26. For breast oncologists, this edition will deliver a new promising biomarker to spare unnecessary chemo, informative updates from practice-changing trials across subtypes, and major innovations coming from China. See you in Chicago next week! #bcsm
Summary of all trials post tki progression in NSCLC.
SACHi
Herthena- lung 02
OptiTrop -lung03
Harmoni global ( presss release)
Mariposa 2
Note that Partitumab is withdrawn by company 2 days ago.
Cross trial comparisons for all 5 trials @dr_yakupergun@Alfdoc2@RenoHemonc@StephenVLiu@ASCO #asco25 @OncoAlert
Presented at #ASCO25:
A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results: https://t.co/j3kWJDjuVz
@ASCO
Presented at #ASCO25:
In HER2-positive metastatic gastric cancer, trastuzumab deruxtecan led to longer survival and better response than ramucirumab–paclitaxel. Adverse events were common. Lung toxic effects with T-DXd were mainly low grade. Full DESTINY-Gastric04 trial: https://t.co/APbBkRhcPO
@ASCO
Today at #ASCO25, I’ll be presenting findings from the VERITAC-2 study on vepdegestrant in ER+/HER2- metastatic #breastcancer, the most common subtype, demonstrating a 43% risk reduction in progression/death for ESR1-mutant patients. @NEJM https://t.co/GHvyyWVebZ
FDA issued final guidance, Use of Circulating Tumor DNA for Curative Intent Solid Tumor Drug Development, to help sponsors using ctDNA as a biomarker in trials under an IND or to support approval of products for treating early-stage solid tumors.
https://t.co/xm4IPGFKRH
A must-read Review on the ever-evolving field of #EGFR mut #NSCLC in@NatRevClinOncol highlighting:
➡️Strategies to improve on 1L 3rd Gen TKI mono therapy
➡️ Ways to tackle resistance post-Osi
➡️Perioperative landscape
@LeXiuning@danieltanmd@RamalingamMD@IASLC#LCSM#some
In the November Issue: The Journey of Antibody-Drug Conjugates: Lessons Learned from 40 Years of Development. https://t.co/qLAy1bDath
By @raffcolo, @PTarantinoMD, and colleagues @ZymeworksInc@DanaFarber