Why are so many inherited traits not explained by genome sequence variation? In my PhD work with @wbderry we describe a new mechanism of inheritance in animals that may account for this ‘missing heritability' 🧵https://t.co/K0tfW4PIoi
We are pleased to congratulate Matthew Eroglu of @Columbia on joining the 2025 cohort of #LeonLevyScholars in partnership with the Leon Levy Foundation. 👏
Learn more about Matthew & meet each of the Scholars in our latest press release.
Read more: https://t.co/6bZFpZPHKA
Congratulations to the 2025 #LeonLevyScholars!🎉
Announcing the 2025 #LeonLevyScholars, in partnership with the Leon Levy Foundation. Recipients participate in a multi-year postdoctoral program to advance their careers.
Read more about the Scholars: https://t.co/6bZFpZPHKA
Congratulations to the 2025 #LeonLevyScholars!🎉
Announcing the 2025 #LeonLevyScholars, in partnership with the Leon Levy Foundation. Recipients participate in a multi-year postdoctoral program to advance their careers.
Read more about the Scholars: https://t.co/6bZFpZPHKA
Small but significant results that led to our amyloid inheritance study
“Regulation of MAP Kinase signaling by the insulin-like growth factor pathway during C. elegans vulval development”
https://t.co/jIgsflOZ5G
"Leaving sticky notes for the children" - Here's a new "Dispatch" @EthanEwe and I wrote in @CurrentBiology about the super cool discovery that @matt_eroglu and Brent Derry had about transgenerational amyloids! (published recently in @NatureCellBio)
https://t.co/bbK7JGmUEM
MoGen researchers at @UofT found that amyloids—proteins tied to diseases like #Alzheimers—can influence heritable traits in C. elegans w/o DNA changes. Published in Nature Cell Biology.
Study led by @wbderry and @matt_eroglu
Read👉 https://t.co/ZqUbPuKBNF
#Epigenetics#DNA
Our neurotransmitter atlas is officially published! This final version includes a lot of extra data (incl. in suppl. files) that weren't in the earlier versions, but I think they could be useful—feel free to check them out!
#neurotransmitter#celegans
https://t.co/kt60FOTAJL
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
@sofiquinodoz Great work, congrats! General question, do all WT nucleoli show phase separation (FC-DFC-GC) or some contexts where this is not observed?
💫NEW: @wbderry, @matt_eroglu & co describe protein amyloid structures that are stably inherited across generations and transmit #EpigeneticMemory in C. elegans. MSTR protein loss results in #transgenerational feminization through ectopic GLD-1 expression.
https://t.co/pFB4NQZ9u5