I had no idea at first, then it suddenly hit me.
1. Normal glomeruli,no FSGS
2. Tubules filled with large granules
3. IF negative=not light chain tubulopathy
Chromogranin +++ in tubules
Dx: Neuroendocrine tumor-associated tubulopathy
65-yr, diabetes, HTN, pancreas mass, ⬆️ Cr
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I’ve been too quiet lately due to a busy work and life schedule. I am finally taking time to visit the USA and go to the Mayo Clinic nephrology update course in San Diego this week :) @MayoClinicNeph looking forward to seeing my colleagues, mentors and friends !
Genetic testing in nephrology is becoming increasingly important to diagnose patients. This Review proposes an algorithm for the assessment of variant of uncertain significance and how some can be reassigned to a diagnostic grouping https://t.co/RKQpmmvBU0
@Nephronette
Fracture Risk Among Living Kidney Donors 25 Years After Donation https://t.co/gb0RPSjaOQ. Proud that @NIDDKgov@NIH supported this work to help understand potential long term effects of living kidney donation to increase safety for current and future donors.
@kidney_boy Yes this is a thing ! this is presuming you are seeing a post-kidney transplant patient with EBV associated post-transplant proliferative disorder :)
Let’s talk membranous nephropathy:
Autoimmune (IgG) response to antigen (Ag) forming IgG-Ag immune complexes along subepithelial region of glomerular base membranes (GBM), along with massive podocyte injury with ensuing proteinuria. 1/10