Max Lam

PI - Neuropsychiatric Genomics Laboratory @ IMH; Deputy Scientific Director PRECISE-SG100K National Precision Medicine Initiative

[Max Lam @maxzylam]

📚 Our findings contribute to a deeper understanding of schizophrenia biology and pave the way for more targeted therapies and interventions. Stay tuned for updates on our cognitive genomics research! #Schizophrenia #Pleiotropy #MedRxiv #NIMH

[Max Lam @maxzylam]

🧬 New preprint alert! Our latest manuscript on MedRxiv investigates the complex pleiotropic genetic landscape of schizophrenia, cognitive function and educational attainment uncovering 768 significant loci – 159 of which are novel. https://t.co/9OJAX9cGrL @ToddLencz

[Max Lam @maxzylam]

🔬 Our new results dissociate forebrain and hindbrain neurodevelopmental processes, and implicate translation initiation factors in schizophrenia pathophysiology for the first time.

[ISPG @ISPGnet]

We are looking forward to 2024 WCPG in Singapore (15th-19th Oct). In the words of our 2024 Program Chairs, "These are exciting times in psychiatric genetics."
Want to learn more? Check out the 2024 invitation to attend: https://t.co/fF65QxeUtm

#psychiatry #genetics

[Max Lam @maxzylam]

@Jimmy_Lee_CK @KeaneLim Thank you to the Phenomics team at the Institute of Mental Health, Singapore! @Jimmy_Lee_CK @KeaneLim Tweetorial to follow soon!

[Jimmy Lee @Jimmy_Lee_CK]

Deconstructing the genetic architecture of treatment-resistant schizop... https://t.co/gHXAltw7Zp
@maxzylam @KeaneLim

[Max Lam @maxzylam]

We are recruiting! DM if you are interested in doing research for precision medicine!

[Nature Genetics @NatureGenet]

🤩 OUT TODAY @NatureGenet
📰 The Singapore National Precision Medicine Strategy
👩🏾‍🤝‍👨🏽 John C. Chambers, E. Shyong Tai, Patrick Tan and team
👇🏿🇸🇬🧬👇🏿
https://t.co/FdbC6JnvHI

[Todd Lencz @ToddLencz]

Pleased to announce the launch of:
https://t.co/Ix42Bx3rkY
The website of the Polygenic Embryo ELSI Research (PEER) Group
(1/5)

[Hailiang Huang @hailianghuang]

Our latest preprint: a novel cross-ancestry fine-mapping method with much improved power and calibration. A collaboration with @kaiyuan1990 @RyanLongchamps @AFPopgen @getian107 @ChiayenChen @YenFengLin @bmneale @dalygene @PGCgenetics among others! https://t.co/5ixdtyWCq9

[Max Lam @maxzylam]

@normacyyyyyy @molpsychiatry Congratulations!

[Yu Chen @normacyyyyyy]

Glad to share this manuscript https://t.co/qPLfq6adF9 which is finally out in @molpsychiatry. Previous studies identified immune gene dysregulations in the brains of patients with several major brain disorders. (1/7)

[Max Lam @maxzylam]

@SherifMorris @NatureComms Here’s the link https://t.co/CUiPVS391f.

[Max Lam @maxzylam]

New manuscript @NatureComms! We leveraged data from 19 cognitive GWAS to disentangle biological mechanisms underlying psychopathology (17 psychiatric GWAS). Some updates from the previous tweetorial! (1/8)

[Max Lam @maxzylam]

A big thank you and shout out to @ToddLencz @ChiayenChen @getian107 @hailianghuang for their valuable insights and help on this effort!

[Max Lam @maxzylam]

The results might provide insights into the potential of nootropic agents targeting specific biological mechanisms to alleviate functional disability within psychopathology. (8/8)