Marcos G. Teneche

PhD student in @AdamsBioAging lab at @sbpdiscovery, former @biologiaub

[Nature Aging @NatureAging]

Online now!✨@anamikaa_yadav et al develop a framework to quantify tissue structural aging, without training on chronological age, using GTEx histology image data, finding distinct and coordinated organ aging trajectories @Sanjusinha7 @sbpdiscovery https://t.co/Ih0gcAkNlo

[Nature Aging @NatureAging]

✨Rajesh et al also report an unexpected role for the cell cycle regulators cyclin D1 – CDK6, as regulators of SASP via DNA damage and cGAS-STING. Blocking this pathway with palbociclib improves motor function and frailty in aged mice @AdamsBioAging https://t.co/z5T4tMEiat

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

Michael Alcaraz, a very talented PhD student, led this study showing that NAMPT activation uncovers a senescence-specific vulnerability and promotes healthy aging in combination with NAM. Small molecule NAMPT activator to boost NAD+, identified at SBP. https://t.co/N22meMRjAG

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

Senescent cells secrete chromatin components via senescence-associated extracellular particles --- New study from recently graduated PhD student in the lab, Lana Zaretski, co-supervised by Malene Hansen @thehansenlab and myself. Great job, Lana! https://t.co/Cd9rbkCOjR

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

For this MS, super post-doc Hiroshi Tanaka chose to manipulate nucleosome stability and assess impact on cell identity, resilience and aging. The data support that idea that nucleosome stability promotes phenotypic maintenance and healthy aging. https://t.co/cT22p9qdq2

[Rong Fan @RongFan8]

New @NatureGenet review from our NIH SenNet ⁦@sennetresearch OMICS WG co-led by ⁦@shenglilab⁩ ⁩
We share practical considerations for identifying, characterizing & spatially mapping #CellularSenescence, plus computational #multiomics insights!! https://t.co/0tzCS4tW6r

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

I'm excited to share this new MS led by fabulous PhD student Adarsh Rajesh "Targeting Cyclin D1-CDK6 to Mitigate Senescence-Driven Inflammation and Age-Associated Functional Decline".
https://t.co/kMWlG0JwgK

[Ani Deshpande @anideshpandelab]

Venoms can kill, but can they also heal? Here's Episode 3 of The Discovery Dialogues Podcast
𝗬𝗼𝘂𝗧𝘂𝗯𝗲: https://t.co/rALBlJg0aX

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

I'm excited to finally share this work led by @FarahJaberH : Inactivation of Histone Chaperone HIRA Unmasks a Link Between Normal Embryonic Development of Melanoblasts and Maintenance of Adult Melanocyte Stem Cells. Published in Aging Cell. https://t.co/0pTh118z4y

[Ani Deshpande @anideshpandelab]

In Episode 2 of the Discovery Dialogues Podcast, we recount the fascinating story of the race to clone the first human gene. Featuring Herb Boyer and Keiichi Itakura. YouTube: https://t.co/ZDcD59v8FZ

[yICSA @YicsaC]

🚨 Calling senescence researchers!
Applications are open for the #ICSARome2025 DEI
& @YicsaC Travel Fellowships 🌍✈️
Need-based & merit-based awards available to attend our annual meeting in Rome 🇮🇹
🗓️ Deadline: May 15
🔗https://t.co/C06pHrr7YT
& https://t.co/ixdn1s8WNZ

[yICSA @YicsaC]

📢 Join our next #yICSA Webinar!
🔬 Silvina Sonzogni will discuss her career, senescence research, & challenges of building a research career in Latin America.
📅 March 28, 12:00 CET
🔗 Register: https://t.co/jimC2isb9t
#yICSAWebinarSeries

[Aging Science News @AgingBiology]

p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells
https://t.co/OGUItIaCa0

[Karl Miller @knmiller71]

Now online, the main paper from my postdoc! A huge thank you to my coauthors, the Adams lab, and Peter @AdamsBioAging

https://t.co/U7DHFWXBqA

[Karthik @karthik_varanas]

With great joy! I want to share with you our recent work on how Bile acid synthesis impedes tumor-specific T cell responses during liver cancer | Science thanks to all the authors and ⁦@Tcellogic⁩ ⁦@salkinstitute⁩ https://t.co/vCJB5q8DsS

[nature @Nature]

Nature research paper: FBP1 controls liver cancer evolution from senescent MASH hepatocytes https://t.co/NsqU2vBSym

[Ani Deshpande @anideshpandelab]

Our institute is excited to host The Myeloid Precursor this Thursday, a fun mini symposium on AML with great talks, a panel discussion on AML, and a poster session. If you are in San Diego this Thursday and interested, please register here. https://t.co/8MFjjLBfTM

[yICSA @YicsaC]

🚀 We're thrilled to announce the launch of the #yICSAWebinar Series, connecting young scientists in the field of senescence! 🌍
Check out our introduction video to learn more about what’s coming up! 🎥
https://t.co/pStYjMixcE

[Peter Adams🇪🇺🇺🇳 @AdamsBioAging]

New study led by talented post doc in the lab @Aaron_Havas : 1) aged tissues at increased risk of cancer due to "precarious balance"; 2) age-activated IFN signaling is an adaptive response to prevent cancer in older tissues, but w/ maladaptive consequence. https://t.co/7matXAcget

[yICSA @YicsaC]

Last day to apply! Don't miss it ✈️✈️