A team has identified factors that drive the recruitment and activation of stem cells to repair skull bone injuries, suggesting defects in this pathway impair bone maintenance and regeneration in humans and contribute to disease. @dental_harvard@YYanglab https://t.co/WsJMGzcqHP
The proteins Cxcl12, Shh, and Ihh act through chemokine and Hedgehog signaling to orchestrate the activation and migration of skeletal #StemCells to repair skull bone injuries in mice, according to a study in this week’s issue. @dental_harvard@YYanglab https://t.co/WsJMGzcqHP
Approved PARP1 inhibitors overcome immunotherapy resistance in breast cancer, scientists identify a trio of proteins that recruit stem cells for skull repair, and more this week in the new issue of #ScienceSignaling. https://t.co/yj2bLq6MOI
July 2023 was the hottest month on record, according to our global temperature analysis. Overall, July was 0.43°F (0.24°C) warmer than any other July in @NASAEarth's record, and it's likely due to human activity. Details: https://t.co/2DTIfL8S1Q
Pericytes Are Odontoblast Progenitor Cells Depending on ER Stress - T. Ouchi, M. Ando, R. Kurashima, M. Kimura, N. Saito, A. Iwasaki, H. Sekiya, K. Nakajima, T. Hasegawa, T. Mizoguchi, Y. Shibukawa, 2025 https://t.co/JoNixx0Qt8
Authors break new ground in defining how PTH1R mediates bone remodeling by identifying a negative feedback loop between PTH1R and IGF1 through the Hedgehog pathway: https://t.co/dVyI6SfoQQ
The cover image shows a mouse molar with co-localization of Gli1+ mesenchymal stem cells (red) and Runx2+ osteoblasts (green) during development.
Findings in this #JBMR article investigating Gli1-lineage cells in various parts of the skull and facial bones enhance our understanding of how stem cells contribute to healing and development in the craniofacial region @OUPMedicine
Read more here: https://t.co/aoLlk7rAIj
Upregulation of Amy1 in the salivary glands of mice exposed to a lunar gravity environment using the multiple artificial gravity research system - PubMed
Space and gravitational physiology have started.
Thank you. https://t.co/Fd9StBVTwB