Unfolded protein response (UPR), by surveillance of protein misfolding, initiating refolding or degradation & inflammation, is involved in aging. As MG is major physiological UPR activator (https://t.co/rm8i46nTq5), @glo1inducer supports healthy aging. @LongevityTech@altos_labs
As we mourn loss of and celebrate life of Judy Campisi, enjoy listening to interview she did for our podcast. It’s great tutorial on #cellularsenescence and her comment on “failed experiments” is classic Judy. Details about memorial service are pending https://t.co/r7g6GvQq4q
I'm deeply saddened to share that we have lost a remarkable friend, a wonderful mentor and esteemed colleague, Judith Campisi. Judith's impact on those around her was profound and lasting. Her legacy will continue to inspire us all. Rest in peace, Judy. You will be greatly missed
Pleased to share my newest publication about OXR1, a gene that protects the aging brain, published today in @NatureComms! A thread describing the results below 👇, and here is a link to the article: https://t.co/tGEKRnXmbC
@KapahiLab#Drosophila#aging#longevity#retromer
What regulates the transport of autophagosomes along the axon? In @JCellBiol, @sydneycason & @ErikaHolzbaur show that mature axonal autophagosomes are transported by the #microtubule motor #dynein, activated by JIP3/4 & regulated by ARF6 & RAB10 https://t.co/fG7YYZnbvM
#autophagy
Today we are gearing up for an unforgettable Linda Partridge Farewell Symposium with a star-studded line-up of speakers - to celebrate her legacy and say goodbye. Let's make this a symposium to remember! 🥂 #LindaPartridgeFarewell
Be careful of eating barbecued food. A simple way to reduce glycation is to cut down sugar, steam food and avoid dry heat. Excited to share the preprint of our article on how a specific endogenous AGE drives feeding behavior and neurodegeneration. https://t.co/8Sd0kY7qOY
Excited to share a preprint of our latest work on how glycation lowering compounds can reduce calorie intake increase insulin sensitivity and extend lifespan even when given late in life. 1/2 https://t.co/UDFSaiyg7h