The common mutations seen in the different types of melanoma. From a lecture by Dr Iwei Yeh today at #ASDP19. CSD = cumulative sun-induced damage #dermpath
Kamino bodies as described by the great Dr Hideko Kamino, the only female dermatopathologist to have a body named after her. #asdp19#dermpath#dermatology#pathology
The WHO has recently decided that sessile serrated adenoma should be termed sessile serrated LESION. I personally think this is idiotic because these things behave like adenomas and SSA is the term coined by Dale Snover Dale found the baby, let him name his baby…
Radiation cystitis is a great pseudo carcinoma! Look to stroma for clues! Stromal hemorrhage, thrombi and reactive atypical stromal cells are useful features. @smlungpathguy@GU_Path_Society@slusagar@Gleason4plus5
It's a malignant phyllodes tumor, these comprise about 10-20% of PTs. Criteria include infiltrative borders, marked stromal cellularity, atypia, abundant mitoses (>/= 10 mitoses per 10 HPF), stromal overgrowth, and can have malignant heterologous elements (not in the pictures).
Leukocytoclastic vasculitis-red cell extravasation, neutrophils, karyorrhexis, fibrinoid necrosis of vessel walls. Nice to find the vessel necrosis on level 1. This is the feature I feel often takes many levels to find. #dermpath#pathology