Matthew S Creamer

Neuroscience CV Starr Fellow at Princeton with Andy Leifer and Jonathan Pillow on modeling calcium dynamics in C. elegans.
NondairyCreamer on Bluesky

[Matthew S Creamer @NondairyC]

What is the relationship between the connectome and the functional properties of the brain? In my new paper we address this relationship in C. elegans using a connectome-constrained whole-brain model to capture how neurons respond to perturbation
https://t.co/1FTQXLdSyC

[Matthew S Creamer @NondairyC]

@neuro_data @jpillowtime 3. As you point out, this suggests that the connectome is highly involved in generating functional interactions. Although it exists in biology, extrasynaptic communication was not necessary to include in the model. Thanks for the feedback! Did that answer your question?

[Matthew S Creamer @NondairyC]

@neuro_data @jpillowtime 2. To address this, we linked anatomy and function with a linear dynamical system which we constrained to the connectome and fit to neural recordings. This model captured both correlations and perturbation responses and performs far worse if constrained to a shuffled connectome.

[HHMI | Janelia @HHMIJanelia]

🐛Janelia Theory Fellow Tosif Ahamed (@_mlechha) is part of a team that developed an AI model that simulates complex animal movements with exceptional accuracy.

Read about this new work, led by @greg_stephens @OISTedu & @antoniocbscosta @InstitutCerveau ➡️https://t.co/shBZ0qnONY

[Matthew S Creamer @NondairyC]

@united cancelled my flight 3 hours before take off. Then their refund system tried to *charge* me $30. Meanwhile, when I didn’t show up to my hotel @HiltonHotels called me. Without me asking they immediately refunded my night. Ocean of difference between these two companies

[Matthew S Creamer @NondairyC]

If you’re at #Cosyne2024 come check out my poster tonight 1-164. I’ll talk about how we can use whole-brain modeling to describe how a connectome can generate neural activity!

[Alexander Bae @jalex_bae]

Check out our newest preprint! https://t.co/NNsBc9uAIM Releasing C. elegans dauer connectome, the last piece of the C. elegans connectomes across development. Work led by talented students @HyunsooYim, @dantae_choe with great collaborators. @SNUNow, @EinsteinMed , #SKKU #KBRI 1/n

[Blake Richards @tyrell_turing]

Coming to #cosyne2023? Wanna go dance on Saturday night? We got you...

We're holding a party at Le Livart (https://t.co/pxdVjenDoQ), with acts:

- Outself (Live EEG gen music)
- Mat Moebius B2B Xanarelle (DJ set + EEG)
- Atelier/Atelier (DJ set + AI gen music)!

Please RT!!!

[Dean Pospisil @deanpospisil]

New publication in J. Neuro (https://t.co/fWIN7jZJbn): the least biased available estimator of tuning curve correlation. Highly relevant to anyone evaluating the similarity of neuronal tuning (this is a lot of people). The classic estimator r^2 is heavily biased. 1/5

[Matthew S Creamer @NondairyC]

@kjungsoo Incredible. But shouldn't the principle components be US, not just U?

[Emonet Lab @EmonetLab]

Excited to share Nirag Kadakia's discovery that flies smell odor motion and use it to navigate odor plumes, published today in @Nature. Great collaboration between our lab and that of Damon Clark. Read it here: https://t.co/57LzUiNBNA and News and Views: https://t.co/ZAsHdOqEt0

[Matthew S Creamer @NondairyC]

Fantastic review on dynamical systems theory in neuroscience

[DurstewitzLab @DurstewitzLab]

Interested in reconstructing computational dynamics from neural data using RNNs?

Here we review dynamical systems (DS) concepts, recent #ML/ #AI methods for recovering DS from data, evaluation, interpretation, analysis, & applic. in #Neuroscience:
https://t.co/fNVdzk0lI5
A 🧵...

[Lidia Ripoll Sánchez @Lidia_Ripoll_S]

Finally out! Proud to present the collaborative effort where we systematically mapped neuropeptide-GPCR interactions biochemically (https://t.co/utkoytWUqC) and constructed an in silico map of neuropeptide signaling in the worm brain https://t.co/e0j10fNUB2

[Matthew S Creamer @NondairyC]

@KordingLab To the poll: in my experience people most often respond dismissively because they believe the science speaks for itself and p values are just a little hat. Its not the best, but also not the worst.

[Matthew S Creamer @NondairyC]

@KordingLab My favorite lighthearted example is when a professor called themselves out... accidentally. They laid out the classic mistake of:
"Exp A shows significance. Exp B does not show significance. Therefore A is different from B."
Then makes this mistake themselves 5 slides later 😆

[Scott Linderman @scott_linderman]

Following the weekend buzz about long range sequence modeling, let me tell you about our work on S5: a simple state space layer that achieves top-level performance and efficiency with parallel scans. (E.g. 98.58% on Path-X!) 🧵[1/12]

[Matthew S Creamer @NondairyC]

@bielleogy I was really hoping you would talk about what you learned about each bullet point!

[Matthew S Creamer @NondairyC]

@SussilloDavid Can you expand on the use case for the co-author network? Just seeing who is working together?