OM

[Medical Sphere @MedicalSphereAI]

Claude Opus 5 is now on HealthBench Professional. 🏥

It debuts 2nd 🥈 on overall score (0.68, mean of 3 runs) behind Muse Spark 1.1 (0.69) and ahead of GPT-5.6 Sol (0.63). On the length-adjusted score it slots into 3rd 🥉 (0.57): its responses are long enough that the length penalty costs it ~0.11, more than either Muse Spark or GPT-5.6 Sol, which moves it just behind GPT-5.6 Sol on that measure.

📊 Leaderboards: https://t.co/qHfewbNGeM
🧪 HealthBench: https://t.co/0mNUniKOjX

[Gary Brecka @thegarybrecka]

Sardines are one of the most nutritionally complete and environmentally sustainable foods available.

A single can provides over two grams of omega-3s, a complete amino acid profile, calcium from the edible bones, Vitamin D, B12, selenium, and CoQ10.

They are also among the smallest fish in the food chain which means minimal mercury accumulation.

[OM @om__aj]

@falsaif متى مدة التصوير؟ وهل ينفع نحمل تطبيقات عليها

[Adam Lababidi @TheDreadCEO]

We spent two years building an AI that takes one goal all the way to the inbox.

That required inventing a new email language. One that renders perfectly in Gmail, Apple Mail, dark mode, even Outlook 2003.

Introducing @Migma_AI

It designs one campaign and adapts it for different audiences and languages. You approve it, and it sends.

It also sends from your own domain, learns from every send, and connects to Cursor, Claude Code or Codex so your agent can wire up your app's emails.

Migma Pro is free for 7 days and 50% off forever for first 200 supporters.

Repost and comment "Migma" and we'll send the access over.

Live today ↓

[Noah Cat @Cartidise]

the Samsung Glasses look way better than the Meta Glasses lol

> Snapdragon AR1 Gen 1 chip
> Android XR platform
> Gemini AI (wearable version)
> No display — audio-only
> Built-in camera
> Voice, touch, and connected-device controls
> Real-time translation
> Real-time navigation
> Designs by Gentle Monster and Warby Parker
> Launching this fall

[The All-In Podcast @theallinpod]

Friedberg: New study shows enzyme reverses skin age from 70+ years to 31

Chamath: That’s a $2T market.

Did Scientists Just Discover How to Reverse Skin Aging!?

“CML is kind of the predominant molecule that gets formed in this extracellular matrix that's driving aging, and nothing breaks it down.

So these scientists set out to try and create an enzyme, an enzyme is a protein that breaks something down, that can break down CML.

And so these guys kind of went out and they took the target, which is CML, and tried to figure out, ‘Okay, how do we actually degrade CML, clear that extracellular matrix, and reverse aging?’

They started to test it on the proteins that we would find in our body, casein, collagen, retinal proteins, which are in your eye, hemoglobin, and they were able to get rid of 52 to 97% of the CML, just degrade it away.

And then they found several sites where they were able to degrade over 90%.

And then they took actual human skin from elderly patients that had donated their skin, and they put this enzyme onto that skin, and they were able to eliminate 55% of the CML on the skin, basically reverse the skin's age down to the age of a 31-year-old, this is from greater than 70-year-old patients, just by putting this enzyme on the skin.

And so it's kind of a groundbreaking demonstration of combination of AlphaFold, what's called directed evolution, where you change the order of the DNA that changes the structure of the protein to test different proteins, do high throughput screening, and ultimately make a novel protein that doesn't exist in nature today that can do something pretty profound for human health.”

Chamath:

“It will be a trillion-dollar market. If you can create a cream…”

Friedberg:

“I mean, dude, if you could put this enzyme literally on your skin and have it absorb in…”

Chamath:

“Game over. That alone is $2 trillion.”

[Health & Nutrition Tips @healthnutritipz]

Electrolytes are underrated.

If you sweat, train, eat low-carb, drink lots of water, or feel flat...

Salt, potassium, and magnesium may matter more than another stimulant.

Hydration is minerals + water.

Not water alone.

[Nick Norwitz MD PhD @nicknorwitz]

1/4) What if you didn't need to sleep?

No, seriously. A new paper in Nature Neuroscience completely blew my mind.

Dare to imagine staying awake 24 hours a day—without sacrificing memory or cognitive performance.

As strange as it sounds, evolution already provides a proof-of-concept.

Certain dolphins, seals, and birds use unihemispheric sleep, where one half of the brain sleeps while the other stays awake.

So, researchers asked: Could we engineer something similar?

(Link to the deep dive at the end)

[OM @om__aj]

@zyloo_io Is there a limit? Or 7 hours free unlimited per user

[Gary Brecka @thegarybrecka]

Eggs are one of the most nutritionally complete foods available and one of the most misunderstood.

A single pasture-raised egg contains all nine essential amino acids, choline for brain and liver health, lutein and zeaxanthin for eye protection, Vitamin D, B12, selenium, and healthy fat.

The cholesterol concern has been largely debunked. Dietary cholesterol has minimal impact on serum cholesterol in most people.

What raises cardiovascular risk is sugar, refined carbs, and seed oils.

Eat your eggs.

[OpenCode @opencode]

there's a lot of excitement around Kimi K3 so we are making it available immediately to OpenCode Go users

we have not yet been able to negotiate a discount yet so it will currently consume your limits at a higher rate

hopefully will figure this out soon

[Kimi.ai @Kimi_Moonshot]

Introducing Kimi K3: Open Frontier Intelligence

🔹 2.8 Trillion Parameters, 1 Million Context, Native Multimodal
🔹 Kimi Delta Attention enables up to 6.3x faster decoding in million-token contexts
🔹 Attention Residuals deliver ~25% higher training efficiency at <2% additional cost
🔹 Built for long-horizon agentic coding and self-evolving workflows

Kimi K3 is now live on on https://t.co/zrk6zZxZUo, Kimi Work, Kimi Code, and the Kimi API.
Open Weights by July 27, 2026.

🔗 API: https://t.co/XCrgjXAqMw
🔗 Tech blog: https://t.co/YTfiMSNM1f

[Abud Bakri MD @AbudBakri]

Lymph/monocyte ratio 🧪

Everyone has longitudinal data on this from their childhood

No one is noticing the decline, especially in the past 7 years

@bryan_johnson look at your ratio that I pointed a few months ago and how this relates to your autoimmune condition

[Kevin Bass @kevinnbass]

Just vibe code slop and get it into production. Go as fast as you can. Later models will make the architecture beautiful in 6 months. That's not your job, human.

[OM @om__aj]

@bercankilic shift

[OM @om__aj]

@myprasanna @vorfluxai @Rippling Consistent components and fronted

[OM @om__aj]

@BitcoinIntelX France 3-1 Spain

[Sawyer Merritt @SawyerMerritt]

California Governor Gavin Newsom signed legislation today creating a new state point-of-sale rebate that gives all first-time EV buyers $3,500 off a new electric vehicle.

• $3,500 off new EVs with an MSRP up to $50,000
• $1,750 off used EVs sold for up to $25,000
• The rebate is open to any Californian buying their first ZEV, regardless of their income level.

If a ZEV automaker is headquartered in California as of Jan 1, 2026, there are no price limits. The rebate initiative carries a total budget of $270 million, with funding coming from both the state budget and automakers.

[Marc Andreessen 🇺🇸 @pmarca]

AI is already a better doctor than 99.99% of human doctors. This is good news.

[OM @om__aj]

@NewYawkGiant @ScoreBetSupport @fifa @NYSGamingComm 2 SHOT on Targets for sure