The Orca manuscript for multiscale 3D genome modeling is now out at Nature Genetics https://t.co/qtMdXU9kKv. Original tweet thread below. Also giving a talk about Orca at ISCB academy in a week.
GraphDR: A linearly interpretable framework for analyzing single-cell omics data improves data representation, visualization and structure discovery. @zhou_jian@OlgaTroyanskaya
https://t.co/MqGr2s4Erk
The new study is the first to look at the impact of mutations in these target sites across the whole genome of people with conditions such as schizophrenia, depression or autism https://t.co/trsnPLy1yQ
Mutations that disrupt binding sites in RNA molecules may contribute to autism and a variety of psychiatric conditions, according to a new study https://t.co/trsnPLy1yQ
An excellent article on our work led by @pazpark demonstrating the major role that deregulation of RBP target sites plays in psychiatric conditions. All predictions shared at https://t.co/eUO09rQFM6
Out today from @OlgaTroyanskaya and colleagues:
Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk | https://t.co/j8sp5zVkEV
@pazpark demonstrates major role of post-transcriptional dysregulation in psychiatric disorders - focusing on variants that disrupt RNA-binding protein binding sites.
I was thinking about some of the comments I received on my F32 NIH postdoctoral fellowship application from 6-7 years ago. It’s surprising how frustrated I still get when I think about it. A thread... 1/
Containing the virus with a two-day work week. 5 lockdown days a week. May eradicate the epidemic while maintaining sustainable reduced economic activity.
https://t.co/gNpqUzTXjY
Excellent!!!
Now get 10,000 random samples
Pool every 100
Most pools should now be negative
If not, either your system doesn't work, or it may actually be good news... (many are infected but relatively few showing symptoms)
This is the scene at O’Hare airport. The traveler who took the photo said it’s a 6-hour wait for bags then on to customs for 2-4 more of waiting in shoulder-to-shoulder crowds. Police are handing out water and disinfectant wipes. @fly2ohare#ord#coronavirus#COVID19