PerformanceProtocol

🧬 Human Biology BSc
💊Stop wasting money on supplements that don’t work
🔗 Supplement Sanity checklist below
⚡️Evidence-based daily health protocols

[PerformanceProtocol @PerformanceProt]

The most most clinically disregarded drug in the last 20 years - MAGIC MUSHROOMS (psilocybin)

Clinically backed use cases:

1. Treatment-resistant depression
2. End-of-life anxiety in cancer patients
3. Alcohol use disorder
4. Tobacco addiction
5. Early case-study signal in Alzheimer's

Mechanism:
- psilocybin activates 5-HT2A serotonin receptors and quiets the default mode network (Rigid patterns loosen)
- BDNF (your brain's growth factor) spikes
- New neural connections form
- Effects from one dose can last weeks to month

How to dose correctly and safely:
- A clinical or legally sanctioned setting, not recreational
- Trained therapist for preparation, the session itself, and integration afterwards
- Medical screening
- Set and setting matter as much as the molecule

The clinical results come from a controlled context

Exciting science

[Chief Nerd @TheChiefNerd]

“Psilocybin, the psychedelic component of magic mushrooms, has previously been touted as an effective treatment for depression, anxiety, addiction, and PTSD — but now researchers say it has the potential to be used in Alzheimer’s intervention as well.

In this case study, published in Frontiers in Neuroscience, researchers focused on an 80-year-old Japanese American woman with Alzheimer’s. She had declined over the previous decade and was reduced to urinary incontinence, speaking in single syllables, and dependence on caregivers for mobility support and daily living.

She was then given a 5g dose of magic mushrooms.

During the initial phase, she was agitated, sweated profusely and entered a prolonged sleep state that suggested unconsciousness. But around hour 19, she began speaking in full autobiographical sentences, recalling life events she had been unable to articulate for years.

In the days and weeks that followed, more incredible changes emerged. She regained urinary continence, even in the evenings, and began dressing herself. She was able to make and maintain eye contact, remember social interactions, emotionally respond to others, and hold lucid conversations.”

[PerformanceProtocol @PerformanceProt]

@arunkumar3112 true

The number your doctor focuses on is often the least informative one on the panel

[PerformanceProtocol @PerformanceProt]

@alexeixbt this is so energising as well

there's truth in 'treat others the way you want to be treated'

[PerformanceProtocol @PerformanceProt]

@limitlesstack 90% of these influencers base their content on bro-science (0 credability)

usually to fit their narrative and funnel followers to their paid products

anyone who can read and understand real science sees through it

[PerformanceProtocol @PerformanceProt]

@TheNutriLab_ This is completely fabricated once again

no credible science backs this up

[PerformanceProtocol @PerformanceProt]

@NTFabiano my personal favourite:

walking

[PerformanceProtocol @PerformanceProt]

@CoachDanGo GLP-1s

[PerformanceProtocol @PerformanceProt]

The supplement industry sells brain health claims on fish oil to the tune of $1 billion/year

This study is why label literacy matters

“Supports brain health” on a bottle is a marketing claim

The research behind it just got a lot weaker.

I break down how to read supplement claims vs actual evidence every week in my newsletter (link in bio) 👆

[PerformanceProtocol @PerformanceProt]

Millions of people take fish oil for brain health

A 2-year clinical trial just proved it doesn’t work

Here’s what the science actually found and what to take instead 🧵

[PerformanceProtocol @PerformanceProt]

What this means

✅ Fish oil as a standalone brain supplement is not supported

✅ Eat oily fish 2-3x/week

✅ No single supplement outsmartsa poor diet

[PerformanceProtocol @PerformanceProt]

@CoachDanGo Haha true I guess

[PerformanceProtocol @PerformanceProt]

@alexeixbt true, but only up to UV 4-5

check other studies around this topic

[PerformanceProtocol @PerformanceProt]

@DeanTTraining this is due to epigenetics

being overweight and having a child increases the likelihood of having a fat child

many studies support this

[PerformanceProtocol @PerformanceProt]

Eating before bed raises your body temperature and heart rate, fragmenting your sleep

If you do need to eat before bed:

a short digestion walk flattens blood sugar spike and speeds up digestion

walking >

[Cooking with Chris @coookwithchris]

Not eating 3+ hours before bed is so much better than skipping breakfast

[PerformanceProtocol @PerformanceProt]

@coookwithchris have you tracked your sleep metrics when eating close to bed?

[PerformanceProtocol @PerformanceProt]

40% correct

“Frequent cold plunges downregulate thyroid” - the acute TSH change from cold exposure is very short and returns to baseline

“Raw cruciferous veggies burden thyroid” - the goitrogen concern applies only at very high intake in iodine-deficient individuals

“Chronic cardio downregulates thyroid” - directionally real in extreme endurance athletes with chronic caloric deficits. Dont apply to the average person

Lots of decent science on here though

[PerformanceProtocol @PerformanceProt]

@paulsaladinomd Not true

plants don’t make any meaningful difference to air quality inside your house

[PerformanceProtocol @PerformanceProt]

Unfortunately, snake plants being able to purify the air in your house is a myth

The famous 1989 study was done in a tiny, airtight lab chamber

In a real house, you’d need about 10 plants per square foot to match an actual HEPA air filter

Buy snake plants because they look nice, not to purify the air lol

Follow for what the science actually says about popular health trends

[Paul Saladino, MD @paulsaladinomd]

snake plant = natural air filter