Kari Hoffman

PI at Vanderbilt University. See @[email protected]

[Kari Hoffman @perpl_lab]

Humor me: I’m reactivating the latest preprint from the lab (itza “new” trace) 🤓

[Saman Abbaspoor @SAbbaspoor]

Experience reorganizes content-specific memory traces in macaques 🐒🧠. @perpl_lab @AymanAljishi

https://t.co/TDx7wYbgE0

[Thilo Womelsdorf @thiwomTO]

Multi-Neuromodulatory fingerprints of an adaptive cognitive state: Cognitive engagement was predicted by joint GABA & ACh/Choline in PFC; by Dopamine & Cholinergic changes in striatum. Glutamate & ACh correlated across states. Kudos to team + Dr Pawliszyn https://t.co/ZixWi7y7g0

[Thilo Womelsdorf @thiwomTO]

2/2 Abilities of inhibitory control, WM updating, and shifting distinguished cognitive phenotypes in NHP's; expl. factor analysis suggested 1) WM updating 2) Shifting/Learning, and 3+4) inhibitory control of interference from external vs internal sources are 4 sep. cogn. factors.

[Thilo Womelsdorf @thiwomTO]

New paper shows causal effects of gaze-contingent stimulation on learning feature-based attention: Treuting et al. (2025) Adaptive Reinforcement Learning is causally supported by Anterior Cingulate Cortex and Striatum. Neuron https://t.co/nEsn6HXW9j
1/2

[Saman Abbaspoor @SAbbaspoor]

Experience reorganizes content-specific memory traces in macaques 🐒🧠. @perpl_lab @AymanAljishi

https://t.co/TDx7wYbgE0

[Denise J. Cai, Ph.D. @denisejcai]

🌟 Cai Lab @Nature paper alert! In new work led by @mysteriousjoe_, we find that rest periods after learning not only stabilize new memories BUT ALSO integrate new memories with older ones from days past! (1/9)

Read it here: https://t.co/Ur8dbGfuP3

[Jason Shepherd @JasonSynaptic]

I am and have been fascinated with how memories are formed and stored. A big challenge, not unique to memory, is synthesizing concepts across scales of anaylsis - from molecules to computation. Here I try to distill how we can move forward in understanding memories. Thanks /1

[Kari Hoffman @perpl_lab]

@Timothy0Leary “Silent” residual Ca++ and WM. Counterintuitive to some, and still not fully embraced in chunks of the literature: https://t.co/7reS5KC7hC

[Kari Hoffman @perpl_lab]

What makes memories last—dynamic ensembles or static synapses? | The Transmitter: Neuroscience News and… https://t.co/mqcd0KOD5a Thanks to @JasonSynaptic for organizing!

[Kari Hoffman @perpl_lab]

Come to U10 U11 this morning if you’re interested in NHP cell assemblies, memory replay, wireless recording 100s of units during learning of new and old context-specific sequences, all in freely moving (and sleeping) monkeys #sfn2024

[Kari Hoffman @perpl_lab]

@Neurocircuits @MillerLabMIT Oh, the intrigue, right?

[Earl K. Miller @MillerLabMIT]

The best event of #SFN2024 or maybe ever.
https://t.co/mLLjGHYjPW

[Vanderbilt School of Medicine Basic Sciences @VUBasicSciences]

New research from @perpl_lab sheds light on the circuit organization that supports memory and spatial cognition. 🧠 This discovery helps with our understanding of how our brains process complex cognitive tasks.

🔗 Read the full study here 👉

https://t.co/26JNsN03EF

[Gal Badihi @Gal_Badihi]

New Paper in @CurrentBiology! Chimpanzees across FIVE communities take rapid turns in gesture-to-gesture exchanges resembling human conversational patterns. Language may not be a pre-requisite for fast-paced, coordinated communication in social species https://t.co/XzpLmCgyCY

[The Transmitter @_TheTransmitter]

Women are consistently under-cited in neuroscience. @anne_churchlandand and @FDavatolhagh share tools that can help assess citation diversity.

https://t.co/x5NX5KxTMQ

[Kari Hoffman @perpl_lab]

@Isotope56 @NeuroPolarbear @NatureComms @MorenoBote Nice to see this out! @Brad_Buchsbaum

[Gord Fishell @GordFishell]

Cortical interneurons learn on the job! Speculated this was true a decade ago! @JJSherryWU and @artofbiology finally provide evidence! https://t.co/cNea65mx5m

[Kari Hoffman @perpl_lab]

@GeorgeDragoi2 @markbrandonlab @NatureNeuro @YalePsych @YaleNeuro @WuTsaiYale @YaleMed @kefei_6 This looks amazing - congratulations!

[Dr. Emily A. Aery Jones @EmilyAeryJones]

Monumental new work from the @GeorgeDragoi2 lab tackles the question of how replay can parallelize, bind, and compress representations of 15 (!) unique linear track experiences: https://t.co/fIyCl4EIxY

[Kari Hoffman @perpl_lab]

@dunmao_ @SAbbaspoor @CellReports @DiagBiochips You bet - shoot me an email and we can chat!

[Kari Hoffman @perpl_lab]

📢The latest from talented @SAbbaspoor 's PhD is out in @cellreports! You into ensembles (@DiagBiochips DA or #neuropixels in #nhp)? ❤️CA1 microcircuits? Wonder why we don’t know how they support #memory or behavior in #primates? Like inhibitory cell types? Cell Assemblies in😴?

[Saman Abbaspoor @SAbbaspoor]

Excited to share that the latest @perpl_lab paper is published in @CellReports. We describe the dynamics of superficial and deep CA1 pyramidal cells and identified putative groups of inhibitory cells in freely moving, thinking, and sleeping macaques. 1/n