NECTIN4 amplification predicts response to Enfortumab vedotin in mUC! It occurs frequently across solid tumors (app. 25% of mUC)➡️potential tumor-agnostic biomarker for NECTIN4-targeting therapies! Happy to share our poster K17 @ASCO#GU24! @Markuseckstein3@OncoAlert@urotoday
Our latest study with @piet_ost, of whole prostates, lymph nodes, and ctDNA at initial diagnosis in de novo metastatic prostate cancer (distant mets) is out in @NatureCancer: https://t.co/6iMFs899iX. 1/n thread 👇
MFS surrogacy for OS in the ‘contemporary’ era - work from #ICECAP confirms validity of MFS as a surrogate endpt for OS in era of greater access to docetaxel and ARPIs for metastatic disease, published in @Annals_Oncology
https://t.co/P8djwoX5Wt
@thorneby Regionerna- har blivit ett försäkringsbolag med en ny affärsidé, vi ersätter allt till alla utom de som verkligen behöver!
Ofattbart att detta får fortsätta, ersättningen för en förkylning borde vara nära noll och registreras något som ger högre ersättning borde man diskas
🔬 The mystery of cancer spread! With a massive database of 25,000+ metastatic patients, researchers uncover the genomic secrets behind metastasis in 50 tumor types.
🧬🧬Chromosomal instability plays a pivotal, yet complex role. Dive into the groundbreaking findings! 🧬 #CancerResearch
@DSolit@DrRosenbergMSK@YJanjigianMD@DrDarrenFeldman@MSKCancerCenter@motzermd @morr316 @OncoAlert@CellCellPress
DOI:https://t.co/Ch6BXlTkR1 (open access)
After CONTACT-3, cabozantinib single agent in metastatic RCC post-PD1 remains a standard, so we urge the #GU community to enroll on @ALLIANCE_org#RadiCAL with Chair @DrRanaMcKay :
-Metastatic RCC (clear/non-clear cell)
-Prior systemic agents
-BONE mets
Patients will be randomized to cabozantinib + radium-223 dichloride or cabozantinib alone
FIND A SITE NEAR YOU!!!!
https://t.co/irDLNwXsuQ
@Dr_K_Rahbar Congratulations Kambiz! This study makes a lot of sense, thanks to you and the team for pursuing this. A bit surprised by the similar HRs for the different compartments, is it an effect of the different magnitude of the volumes ?