Thrilled to share our new paper in Science! 🎉
We uncover how dietary fat–driven ceramide synthesis activates YAP-dependent regenerative programs to promote colorectal cancer metastasis, independently of primary tumor growth.congrats @SwagataGoswam16 https://t.co/5fy0prv40Q
AI 4D Cell Biology!
Watch mitochondria reveal their hidden phenotypes! We built MitoSpace, a self-supervised model trained without labels on terabytes of 4D lattice light-sheet movies of single cells. It learns representations that outperform predefined features, predict membrane potential from 4D form alone (R²=0.91), and generalize zero-shot to unseen drugs and human lung organoids.
🎉 Now published in @CellCellPress!
With @DrvAgwl@ZacharyWang379@ecarkfeld@andremodolo4@Parth_LFC@hhako2@GCMcMahon
📄 Paper: https://t.co/KmoUvFOYAk
🔬 Explorer: https://t.co/asVHY1s028
💻 Code: https://t.co/AUHVSg4aRr
🤗 Model: https://t.co/2vJvQRmDjj
#AI4DCellBiology #cellbiology #microscopy #LLSM #latticelightsheet #mitochondria #deeplearning #phenomics
Excited to share that my paper, "Genome-wide CRISPR Screening Reveals a PKA-Driven Resistance Mechanism to Metformin for Oral Cancer Prevention That Can Be Exploited by Combination with NSAIDs" has been published and featured on the cover of this month's issue of @CAPR_AACR!
In this review, we highlight the possible use of recombinant type I and type III IFNs to combat #COVID19. The key is to use IFNs early or even before infection.
@BioRender made all these figures super easy to prepare 👍🏽 #SciComm
In some children, #COVID19 takes the form of #KawasakiDisease-like symptoms. So what exactly is #KawasakiDisease? It's an illness caused by inflammation of the blood vessels in children < 5 yrs of age. The exact cause is unknown but here's what we do know. Thread (1/n)