pines

Neuroscience stuff | Postdoc @Stanford_PMHW | |

[CLaE @leafs_s]

PNAS

Traveling-wave transcranial alternating current stimulation (twtACS) causally links neural timing to cognitive function

This study developed a new brain stimulation method called traveling-wave transcranial alternating current stimulation (twtACS). Unlike conventional brain stimulation, twtACS creates electrical waves that move across the brain in a specific direction, similar to natural neural traveling waves.

The researchers showed that these artificial traveling waves could:

Change the timing of neural activity in the brain
Control how signals propagate across brain regions
Improve cognitive performance in humans depending on the direction of the wave

They confirmed these effects using:

Human intracranial recordings
Monkey neural recordings
Human behavioral experiments

The study suggests that traveling waves are not just correlated with cognition but may causally influence cognitive function. This introduces a new way to noninvasively manipulate brain communication and potentially treat neurological disorders.

https://t.co/FnOQwNlB30

[SAWilke @ScottWilke5]

How does TMS — a treatment for depression — reshape dysfunctional brain circuits?

In our new Cell paper, we identify a cell type-specific prefrontal mechanism linking accelerated iTBS to antidepressant-like behavioral effects and circuit plasticity.

https://t.co/XVx9fZ4M9d

[Nicholas Branigan @NKBranigan]

What are the neural correlates of human behavior?

Much research has approached versions of this question between individuals but not within individuals. Are results from these 2 approaches similar? No!

In over 4000 individuals, the neural correlates of cognitive control diverged between vs. within individuals -- a case of non-ergodicity and Simpson’s paradox.

We think that non-ergodicity may be an important principle in human neuroscience. [1/12]

[Steven Meisler @StevenMeisler]

Diffusion MRI (dMRI) is a powerful tool to study white matter maturation. In our new preprint, we process and distribute a new resource of >24,000 ABCD dMRI scans using open source tools! We then evaluate how methods shape inferences about development.
🔗 https://t.co/XzEFQQj6i9

[XiaoboLiu-刘晓波 @XiaoboLiu29]

Our first work from my PhD period: https://t.co/nD1XIYWPg3

In this study, we propose a computational model and theoretical framework for neural dynamics. This is only a starting point, but it also reflects our broader academic ambition.

[Audrey Luo @audreycluo]

We think of white matter as highways of the brain. But when we followed development along those highways, we were surprised. The journey is more complex than we thought. My PhD paper, “Two Axes of White Matter Development”, is now out in @NatureComms!🧠

🔗https://t.co/qR3tyH0y90

[Ellyn Butler @EllynRButler]

My second first author paper of graduate school - Sex differences in response to violence: role of salience network expansion and connectivity on depression - is now published in Translational Psychiatry! https://t.co/aXUKZLPFqn

[Isaac Kauvar @ikauvar]

Emotions are core to the human experience 😆😮🙂😊☹️😠😳😑. But how do they arise? Our brain-wide ⚡recordings in humans and mice reveal some answers @ScienceMagazine. A big team effort and debut paper from @Stanford's new Human Neural Circuitry program. https://t.co/FbbJIjky2c

[pines @pineurosci]

Congrats Paula!!

[Paula Muñoz Rodríguez @Paula_MunozR]

🧵1/7 New paper out! We explored how cognitive behavioral therapy (BIT+) affects brain activity & inhibitory task performance in hoarding disorder. Thankful for @CRodriguezMDPhD @LMWilliams_PhD @pineurosci @pineurosci @Stanford_PMHW @warmxue mentorship! https://t.co/CtzUK1tbKy

[pines @pineurosci]

The electric fields given off by TMS are super distributed: this is a great one for piecing apart the implications of that spread for individual treatment outcomes. Congrats Divya!

[Divya Rajasekharan @divyardotdotn]

Check out our recent work demonstrating that the scalp-based Beam/F3 method is a reliable way to target the dLPFC in #TMS for depression! We learn more by integrating personalized E-field models… 👀
With @NoahSPhilipMD, @LMWilliams_PhD, and others.

👉 https://t.co/iIhjLJS5Gv

[Alessandro Gozzi @Gozzi_Ale]

Breathing isn’t just for life—it’s a brain pacemaker!
This excellent review reveals how each breath sends sensory waves that globally synchronize neural networks - with implications for "functional connectivity". Congrats to the authors!

👉 https://t.co/wpD8K9ShgJ

[Jake Vogel @_JakeVogel_]

‼️PhD Position now available in my lab‼️

Do you like:
* Neurodegenerative disease?
* Neuroimaging and/or multi-omics?
* AI and data-driven life science?

Want to work with @RikOssenkoppele Alexandra Young and Laura Wisse?

Apply here: https://t.co/aQ3g5pZWJe

Please rt/share 🙏

[pines @pineurosci]

Seems relevant to all the white matter targets popping up in brain stim. Not just a highway anymore!

[Audrey Luo @audreycluo]

We think of white matter as the brain's highways—uniform conduits between cortices. What if we study development along tracts? Turns out the journey matters as much as the cortical destination! We're thrilled to share “Two Axes of White Matter Development”https://t.co/SYU2rRkvqr

[ZaixuCui @zaixucui]

Thrilled to announce our study, “Connectional Axis of Individual Functional Variability: Patterns, Structural Correlates, and Relevance for Development and Cognition,” now published in @PNASNews https://t.co/BU1Dnj6Kn4

[Andrew Moses Lee @AndrewMosesLee1]

Our preprint detailing our novel approach to identifying personalized neuromodulation targets to treat severe, refractory OCD using brain mapping is now out on MedRxiv. Here, we describe our first SEEG-guided DBS case for OCD at UCSF: https://t.co/YwvchuPHGO

[Golia Shafiei @goliashf]

(1/17) Now out on bioRxiv‼️Reproducible Brain Charts: An open data resource for mapping brain development and its associations with mental health | https://t.co/ZSymcPIJ7c

Funded by @NIMHgov

[pines @pineurosci]

!!!

[Andrew Pines @PinesAndrew]

What brain regions are involved in causing psychotic symptoms?

Take a moment away from the existential dread about the future of science, and join me in this summary of some incredibly cool stuff that could help patients!
1/n🧵

https://t.co/sBV6Lf12lR

[Aurina Arnatkevičiūtė @AurinaArn]

Our work linking GWAS and pharmacological treatments in psychiatric disorders is now in JAMA Psychiatry https://t.co/5MYupMDS5M
🧬💊🎯

Big thanks to @bendfulcher @AFornito @BellgroveMark
🧵👇

[Sarah Chang @Sarah_Chang_]

Now out in @NatMentHealth 🥳🥳🥳 this is the 2nd study of my dissertation with Carrie Bearden, co-led with @dehughes14 💫💫https://t.co/OQkxGdsAqT

[bioRxiv Neuroscience @biorxiv_neursci]

Topography of putative bidirectional interaction between hippocampal sharp wave ripples and neocortical slow oscillations https://t.co/7opBL0Qs3z #biorxiv_neursci