WHaloForce enables chemigenetic imaging of molecular tension in living cells and animals. A wonderful collaboration with Shaohe Wang at HHMI Janelia. https://t.co/IHzx2gj1cZ
🧵1/n Excited to share our new preprint on CTCF dynamics. The small but powerful CTCF binds only ~20 bp, yet controls Mb-scale chromatin loops by directionally capturing a ~7x larger cohesin complex racing along DNA at 1-3 kb/s. How does CTCF do this?
Check out our latest work on BioRxiv
"The human RAD52 complex undergoes phase separation and facilitates bundling and end-to-end tethering of RAD51 presynaptic filaments"
From the Ha lab @taekjip and the Spies lab @maria_spies
A summary thread (1/n)
https://t.co/4krp5X0u1i
Our focus issue on RNA biology features reviews that explore the many faces of #RNA, diving into the processes mediating the lifecycle of RNA, the regulatory roles of RNA, the importance of RNA in disease, and the technologies used to study RNA. https://t.co/Y4hNLNC5zz
Exciting news! Our latest work used fluorescence correlation spectroscopy to track heterogeneous protein aggregation at the nanoscale, showing that FCS can detect this at concentrations one order of magnitude lower than traditional bulk techniques.
https://t.co/fGEoXW5DnK
It’s official: I’m proud to share that I’ve been selected to be one of the @ActivateFellows as part of #ActivateCohort2024! This program is a game-changer for my research, helping to bridge the gap between the lab and the market. Looking forward to this incredible journey.
Thank you JCC for the support. It's an honor to be a part of this years cohort. Deeply grateful for TJ Ha @taekjip for his mentorship and my Ph.D. advisor @BanerjeeLab_UB! Also thank you to all my past mentors for their continuous support!
I am stunned and truly honored that I am the recipient of the 2024 Raymond and Beverly Sackler International Prize in Biophysics - together with @leonidmirny and @SchwilleLab!
https://t.co/Xlzzc2WR8s
What an incredible honor to receive this prestigious prize!
#humbled#thankful
Rapid Long-distance Migration of RPA on Single Stranded DNA Occurs Through Intersegmental Transfer Utilizing Multivalent Interactions https://t.co/OVb9Y55g7U
Think about a race. RPA is like a really fast runner that can skip parts of the track (DNA) to reach the finish line faster. It does this with the help of many different pit stops (interactions).
Congratulations to all the amazing poster presenters. Awards were given to Sushil Pangeni @taekjip, Sahil Batra @LabRemus, Alex Duckworth @kecklabuw, Hardeep Kaur @PatrickSungLab, Mihai Solotchi (Patel Lab), Gable Wadsworth @BanerjeeLab_UB, Lauren Herr @BobBrosh
As he prepares to enter his tenure as President, Taekjip "TJ" Ha shares his hopes for the year ahead and reflects on the value of getting involved with BPS leadership.
https://t.co/FM0uaqipM6 #BPS2023@BiophysicalSoc
Promoting #Zinc staining which is as sensitive as that of #Silver staining and it takes ONLY 360 seconds!!!
1) Rince the gel with water 30 seconds
2) Shake the gel in 0.2 M imidazole 300 seconds
3) Soak the gel in 0.3 M Zinc Chloride 30 seconds!! And the magic happens 👇👇👇👇