Prasanth Ganesan

Scientist at @StanfordMed. Previously AI research fellow at NIH @nlm_lhc. Forbes 30 under 30. Signal processing and Machine learning. Views are my own.

[Prasanth Ganesan @prash030]

Day 2 of #HRS2026 - presenting my poster on foundation models to predict cardiomyopathy from 12-lead ECG. Lot of interest in the field for #AI of #ECG 🎉 Thanks to my mentor Dr. @S_NarayanMD and to all my coauthors and collaborators! @ajrogers_md @TinaBaykaner @StanfordMed

[Sanjiv Narayan @S_NarayanMD]

Amazing work @prash030 on #foundationmodels to predict #AF outcomes

[Prasanth Ganesan @prash030]

Great first day of #HRS2026 ! Loved the #AI sessions and did a lot of networking. Looking forward to tomorrow's sessions. Check out my poster presentation PO-02-318 tomorrow from 12.30-2.30pm.

[Prasanth Ganesan @prash030]

At Stanford Biodesign conference. Many interesting and insightful sessions!! @SUBiodesign @S_NarayanMD @TinaBaykaner @NTrayanova

[Prasanth Ganesan @prash030]

@BehnazGhoraani @Sensors_MDPI Congratulations🎉

[Prasanth Ganesan @prash030]

@shirin_sadri @S_NarayanMD @Sabya_Bando Congrats, Shirin! Great working with you!

[Shirin Sadri, MD @shirin_sadri]

#AHA25 was the best! Got to present our work in @S_NarayanMD lab with @ Kelly Brennan, @Sabya_Bando @prash030 using large language models to detect VT recurrence in clinical notes and enable prediction of outcomes, towards precision pharmacotherapy in VT.

[A.J. Rogers @ajrogers_md]

See here for the associated publication: Deep learning–based continuous QT monitoring (3DRECON QT) reconstructs 12 lead ECG data from a single lead monitor to predict QT/QTc. https://t.co/IjSsjSXC8d
@davidouyang
@prash030
@kbrenn711

[Circulation @CircAHA]

#AHA25: Deep learning–based continuous QT monitoring (3DRECON QT) reconstructs 12 lead ECG data from a single lead monitor to predict QT/QTc. It detects QT prolo... https://t.co/1daUjvE2ep @Wanginnovate @mvperez92 @AlexanderPerino @davidouyang @prash030 @kbrenn711 @ajrogers_md

[Sanjiv Narayan @S_NarayanMD]

#ep_peeps #StanfordEP25 FRIDAY OCT 24TH 8A-4P PT Register to discuss latest #AF #VT #innovations via #AI & case #efficiency with @EPrystowskyonEP Isabelle Diesenhofer @DrBradleyKnight @james_y_zou @netta_doc @TinaBaykaner @Wanginnovate
In person/stream https://t.co/X1ZZ3pXziS

[Prasanth Ganesan @prash030]

@BehnazGhoraani Congrats!

[Jeff Dean @JeffDean]

Check out our state-of-the-art open weights MedGemma multimodal model for making sense of longitudinal EHR data as well as medical text and medical imaging data in various modalities (radiology, dermatology, pathology, ophthalmology, etc.)

See the blog post linked below! ⬇️

[Floor Eijkelboom @FEijkelboom]

Flow Matching (FM) is one of the hottest ideas in generative AI - and it’s everywhere at #ICML2025.

But what is it? And why is it so elegant? 🤔

This thread is an animated, intuitive intro into (Variational) Flow Matching - no dense math required.

Let's dive in! 🧵👇

[Jay Lu, DPhil @jayjay_lu]

Curious about optical mapping techniques for cardiac research? Here's a quick video demonstrating the optical mapping recording and analysis of mouse atrial electrical activity (Ca²⁺ and AP).

@MappingLab #cardiotwitter #electrophysiology #Cardiology #calcium #actionpotential

[Khaled Saab @_khaledsaab]

Gemini powers our multimodal health research! 💙

In our new paper on multimodal AMIE, we're pushing conversational diagnostic AI beyond text to handle images such as skin photos, ECGs, and clinical docs, which provide crucial context in healthcare.

Blog: https://t.co/VAlKoR53Il
Paper: https://t.co/2zHQT0H5Pv

How do we make an AI reason like a clinician during a dynamic, multimodal conversation? One of our key contributions is multimodal state-aware reasoning, built on @GoogleDeepMind Gemini 2.0 Flash.

Instead of just reacting turn-by-turn, AMIE maintains an internal "understanding" of the consultation:
✅ What is known about the patient?
✅ What are the likely diagnoses?
✅ What information (text or visual) is missing?

This internal state allows AMIE to:
👉 Intelligently guide the conversation through phases like history-taking & diagnosis.
👉 Strategically ask for relevant images (like skin photos or screenshots of ECGs/docs) when its internal state shows uncertainty.
👉 Accurately interpret multimodal data and weave the findings back into the ongoing dialogue and diagnostic process.

Essentially, it mimics the adaptive reasoning clinicians use, leading to a more structured and effective consultation.

We evaluated multimodal AMIE against primary care physicians (PCPs) in a demanding, blinded OSCE study using 105 diverse multimodal scenarios.

The results demonstrate clear progress: AMIE achieved similar or superior performance when compared to PCPs across a wide range of metrics, including diagnostic accuracy, empathy, and critically, the handling and reasoning about multimodal data.

While the OSCE results are very promising, it's important to remember this was a test environment with patient actors! Real-world care is more complex. Making sure it's safe, reliable, and actually helpful in the real world needs more work, starting with our upcoming study with Harvard BIDMC.

The work would not have been possible without an amazing team @GoogleAI, @GoogleDeepMind: @RyutaroTanno, @alan_karthi, @vivnat, @AdamRodmanMD, @timstro, @taotu831, @hardyshakerman, @JanFreyberg, @_cjpark, @yasharmaa, @apalepu13, @arkitus, @weballergy, @valentinlievin, @ckbjimmy, @davidstutz92, @dgtbarrett, @yongcheng16 @SaraM66905, @dr2w, @ymatias

[JK Han MD @netta_doc]

Great reminders from @S_NarayanMD re: Mapping in the current era - we still have work to do!

* EGMs ≠ Action Potentials
* How to we compare across #AI models? Very tough to do
* with implementation of AI, outcome & workflow need better synchronization

#StanfordBiodesign2025

[Prasanth Ganesan @prash030]

Why do we need #AI in #cardiacEP ? AI models can do tasks beyond humans' capability. Learning features unknown to humans, forecasting, automated remote monitoring, etc. Need more collaborative efforts to bring AI into practice. Great talk by @TinaBaykaner45! @SUBiodesign

[Prasanth Ganesan @prash030]

Happening now: Stanford Biodesign New Arrhythmia Technologies Retreat at #SanDiego ! Opening remarks from @Wanginnovate @S_NarayanMD . Great talks coming up!

[Prasanth Ganesan @prash030]

@FAU_ISENSE @BehnazGhoraani Congratulations🎉🎉

[FAU I-SENSE @FAU_ISENSE]

🎉 Proud moment! I-SENSE Faculty Fellow @BehnazGhoraani, a leader in biomedical data science & smart health tech, is FAU’s Scholar of the Year! Honored at the 56th Honors Convocation for groundbreaking research improving global health. 🌍❤️ #FAU #Innovation #GoOwls