CEO @myomeinc. Previous President/Co-Founder @ciitizencorp (acq by Invitae). Investor. Solving hard problems. All views are mine. By way of @caltech and @umbc.
LARRY ELLISON: AI IS RAPIDLY COMMODITIZING BECAUSE MOST MODELS ARE TRAINED ON THE SAME PUBLIC INTERNET DATA.
THE REAL COMPETITIVE EDGE ISN’T THE MODEL ANYMORE — IT’S ACCESS TO EXCLUSIVE, PROPRIETARY DATASETS.
THAT MAY BE THE ONLY MOAT LEFT.
UC STEM faculty are absolutely right, and this change is long overdue.
We’re doing our kids a disservice and putting at risk the reputation of the world’s best public university system. As Governor, I’ll bring back SAT/ACT scores as part of the admissions criteria for STEM degree applicants.
I just had the craziest experience at the airport.
We are about to board a flight to Atlanta when the pilot from the incoming plane walks out of the jetway. Guy is probably late 50s, salt and pepper hair, military look. The kind of pilot you instantly feel good about seeing on your flight.
Pilot walks over to the counter, gets on the PA system, and starts addressing everyone. “Folks, I’ve been doing this a long time. Flying one of these jets is easy. The hard part is looking at 130 people and telling them their flight is going to be delayed.”
Audible groans throughout the boarding gate. Most people here are flying to Atlanta as a layover before another flight. 130 people just had their day become a complete mess.
The pilot goes on. “I get it, trust me. But here’s the deal: During our landing, we had a small mechanical issue. I’m not your pilot for the next leg, but I don’t feel confident the jet’s safe to fly until we have a mechanical team look it over, and I don’t feel comfortable asking the next pilots to fly you guys until we get confirmation.”
He points at the agents next to him behind the counter: “Now, none of this is the agents’ fault. Please be kind to them. I’m the one who made this decision, not them, so any inconvenience you experience is my fault. Just please know that I don’t do this lightly, and I’m only doing it because I believe it’s in the best interests of everyone’s safety.”
Now this is where the story gets crazy. The pilot puts the microphone down, grabs his suitcase, and all the people in the gate…
Start clapping.
I’m not joking, everyone starts clapping for the guy. 130 people who just had their travel plans ruined give an ovation to the guy who made the decision and delivered the message.
All because he addressed them with decency and transparency, took ownership of the decision, made it clear that it was necessary, and explained why it was in everyone’s best interest.
It’s honestly one of the best examples of strong communication—of strong leadership, for that matter—that I’ve seen in a long time.
@Delta, whoever your Atlanta to Wichita pilot was this morning, he’s one of the good ones. Please tell him the delayed passengers of flight 1637 appreciate what he did.
I’m doing parenting all wrong: apparently they do just give out participation trophies and made up awards throughout your adulthood. https://t.co/7iS46S07OY
@MattMahanSJ and @DanielLurie are the two best mayors in the country and Californians would be wise to get to know Matt. Moderate, pragmatic and knows what it means to govern.
San Francisco’s Chinatown is special. Grateful for the warm welcome, the conversations, and the reminder that San Francisco’s beauty has always come from the people who keep the community and culture alive.
Statistics are hard for so many and bastardized for their own interests. There’s a reason median is used in most financial metrics. The top 1% is likely skewing the average. Median is probably so much lower.
The average American has about $5,700 in gold jewelry sitting around their home.
Unvault has created a streamlined way to understand what you own, then you can choose to safely sell the gold.
This could be incredibly impactful for a family.
Rachel Entrekin just ran across Arizona on five-minute naps. She covered 253 miles, nearly 10 marathons back to back, in 56 hours and 9 minutes. Faster than any human has ever done it.
The race starts in the cactus desert near Phoenix and ends in Flagstaff. Runners climb 38,791 feet over the course (taller than Mount Everest). They descend almost 34,000 feet. Daytime in the desert hits the 80s, while overnight on Mount Elden it drops below freezing. The cutoff is 125 hours, and most finishers need every minute of it.
The course runs across trail, rocky dirt roads, and pavement. She held a 13-minute-mile pace, the speed of a steady jog, for two and a half straight days.
Researchers tracking 119 ultramarathon runners found that 74% of people in 100-mile races don't sleep at all during the race. Past 200 miles, the body breaks. Most racers stop and sleep for hours at a time. Entrekin took five-minute dirt naps and kept moving. Her closest rival, Kilian Korth, who won the three biggest 200-mile races in 2025, tried the same five-minute strategy. It didn't work. He ended up sleeping for an hour and finished 78 minutes behind her.
Going that long without sleep is medically dangerous. A 2023 review of ultramarathon research found that in one 152-mile mountain race, about a third of runners who slept under 30 minutes had visual hallucinations. Seeing things that aren't there usually starts after about 24 to 48 hours awake. Severe loss of touch with reality, often called acute psychosis, sets in between 48 and 90 hours. Entrekin ran straight through that entire window without stopping.
Her three Cocodona times: 73:31:25 in 2024, 63:50:55 in 2025, 56:09:48 this year. She has cut 17 hours off her own time in three attempts. The previous overall record, set by Dan Green, was 58:47:18, and Entrekin beat it by 2 hours and 37 minutes. At the finish, she said: "I feel fine, that was insane."
In another episode of fixing #healthcare is janitorial work, @SutterHealth has sent me many bills, and now a threatening letter to send to collections. But EVERY method of trying to pay them has failed. Desktop, mobile. Different methods. Same issue. All the AI in the world, but…
@FIFAWorldCup and @FIFAcom got drunk on the US market and came out of the gates with crazy high prices. Secondary markets went even higher. Add the increasing cost of flying due to high fuel prices and price gouging by some locales on public transport and here you go.
Nearly 80% of U.S. hoteliers in 11 World Cup host cities say bookings are tracking below original forecasts, with some describing the tournament as a “non-event,” according to an American Hotel & Lodging Association (AHLA) survey of members released Monday.
Read more: https://t.co/aLGJAHn9rW (Photo: Dustin Satloff via Getty Images)
The Trail Blazers are widely expected to move on from interim coach Tiago Splitter.
New owner Tom Dundon is not willing to increase Splitter’s current salary.
Portland is trying to find a new head coach who will accept being the lowest paid in the NBA as a cost-cutting measure.
Before shots fired at the WHCD, I got to meet @danawhite. No matter what you think about his politics, the guy couldn’t have been nicer and has boundless energy. Took the best pic with us, smiling ear to ear like he’s always known us. I can see why he’s successful.
The Hilton donated the ~2600 dinners that went unserved at WHCD. They freeze dried the steak and lobster for longer shelf life before giving them to 2 shelters for abused women and children. HUGE thank you to the staff that worked through the night under terrible circumstances.
@LeoFeldmanNEWS@dcpoll Yes. Was there and we all thought the same thing. Checked in at the hotel at 1:30 and it was as if nothing was happening. Found it odd that I could just stroll into the building where so many important people would be in a few hours.
Polly, I think your account is fine and I align with a lot of your views but I was in that room and there’s no place to mock anyone (even this president) that has violence targeting them. It was scary for everyone in there and there’s no place for this shit regardless of your political bent.