Prostate volume doesn't reliably predict obstruction — and we've known it for decades. A new open-access review in PCAN introduces a new concept: periurethral and transition-zone fibrosis is an under-recognised, untreated driver of LUTS/BPH.
The case for antifibrotics: pirfenidone, losartan, PDE5-i, even halofuginone. https://t.co/vIw1BF5CJs
🆕 Happy to share our review on distal urethral strictures, recently published in International Journal of Reconstructive Urology:
At the tip of the problem: Surgical strategies for meatal and fossa navicularis stricture repair
https://t.co/HQBQ9pz3gL
Urge incontinence trick: toe curl, heel raises, or quick pelvic floor squeezes activate the sacral reflex arc and inhibit the overactive detrusor contraction — buying time to reach the bathroom safely.
Simple. Evidence-based. Life-changing for OAB patients.
https://t.co/PSqfEB4wRN
📢 Exciting Read for Radiologists and Urologists🚀
📚Just came across this fantastic educational article in @RadioGraphics “PRECISE Version 2: Essential Tips for Prostate Cancer MRI Reporting”
🔔This paper is a must-read for anyone involved in prostate MRI!
✅It provides clear, practical guidance on using the updated PRECISE v2 system to standardize reporting for patients on active surveillance.
👍Key highlights include refined scoring for assessing disease stability/progression, helpful checklists, case examples, and tips to reduce ambiguity in serial MRI interpretation!
💡Whether you’re a radiologist fine-tuning your reports, a urologist discussing imaging with your patients, or a trainee building your skills — this valuable resource makes complex concepts more approachable and clinically impactful!
🥇Congrats to @giga_fra and the entire team for this nice work!
🔗 Full article: https://t.co/aDDs0diGET
#Radiology #ProstateCancer #MRI #ActiveSurveillance #RadioGraphics
Bipolar enucleation = winning on every front
💰 Cost-effective/ No machine breakdown 🫡
🩸 Excellent hemostasis
🧠 Anatomical dissection
🛡️ Less stress on the sphincter
✋ Superior tactile feedback → easier plane recognition
🚫 No postoperative irrigation
🏃♂️ Discharge after one spinal anesthesia session
🔥 POISE-3 Urology published in European Urology 🚨
In the largest randomized placebo-controlled #urology analysis of #TranexamicAcid (TXA), #TXA reduced major #bleeding risk by 37% (from 9.5% to 6.1%) with no clear increase in #thrombosis
More at https://t.co/Yypy7vb9Jz
#EBM
New paper in World J Urol: En bloc HoLEP with vesical mucosal release — a technical refinement by Gomez-Regalado et al. Protecting the ureteral orifices by incising the vesical mucosa. Simple idea, elegant solution, now published.
https://t.co/OW5xjCL3Vf
https://t.co/GINvYb0OtW
🧪🚀 A new uPSA/uZinc urine test shows promise in prostate cancer detection:
✔️ Improves diagnostic accuracy (especially with mpMRI)
✔️ Could avoid ~50% of unnecessary biopsies
🔍 A step toward smarter, non-invasive, personalized care!
🔗https://t.co/w7YgeikJ3V
📊 MRI PI-RADS may not fit all populations equally:
➡️ Black men: +20% higher risk
➡️ Asian men: PI-RADS 3 lesions all negative
🔍 Time for more personalized diagnostics!
👉https://t.co/dUk3zj4nlZ
Among men with locally advanced prostate cancer, transdermal estradiol was noninferior to LHRH agonists for 3-year metastasis-free survival and led to a lower incidence of hot flashes but a higher incidence of gynecomastia. Full results of the STAMPEDE-1 and PATCH trials: https://t.co/sKJ6Sr6WiW
Kidney cancer care just got a major upgrade.
The NICE 2026 guideline finally gives a full roadmap for RCC, from diagnosis → treatment → follow-up.
⚙️ What changes in clinic:
🔬 Biopsy matters more
• Recommended for small renal masses (≤4 cm) when it impacts decisions
👀 Active surveillance is legit
• Now standard option for selected small tumors + Bosniak 3 cysts
🔪 Surgery still leads
• Remains gold standard for many localized cases
🔥 Non-surgical options
• Ablation / SABR for patients unfit or unwilling for surgery
📊 Follow-up gets smarter
• Risk-adapted imaging instead of one-size-fits-all
👨⚕️ Team-based care
• Strong push for MDT + clinical nurse specialist access
💡 Takeaway
👉 Less overtreatment, more personalization, better structured RCC care
🔖 This will change real-world practice more than most trials.
📖 Full paper in comment ⬇️
#OncoTwitter #MedTwitter #KidneyCancer #RCC
@OncoAlert@myesmo@esmo_open@asco
Obesity is linked to at least 12 cancers.
Here’s part of the biology in @JAMA_current
Dysfunctional adipose tissue becomes a pro-tumor endocrine organ, driving insulin signaling, estrogen excess, chronic inflammation, and immune suppression.
In other words: obesity can help create the ecosystem cancer needs to grow.
https://t.co/o9OHokqMuJ @OncoAlert
Excited to announce that my book "The En bloc HoLEP Manual" is coming out.
Get your copy at the Wisepress stand during EAU26 in London this Friday — limited copies available.
Also coming to Amazon in English and Spanish in just a few days.