Rob Borkowski 🧬

I think your genes look great on you. | RWD @NateraGenetics | Previously Product & Science @23andMe @color @broadinstitute

[Rob Borkowski 🧬 @rborkows]

I’d go so far as putting Claude at “replacement level” EQ, better than a whoooole lot of the valley.

[Shreyas Doshi @shreyas]

Claude today has greater empathy than the 90th %ile people manager at a tier 1 silicon valley tech company.

[John O'Connell @jacko2323]

So now we’re good at soccer and we’re good at surrendering. We’re officially European!

[Rob Borkowski 🧬 @rborkows]

@TechnoTimLive I saw it in release notes but was never able to find it in the UI!

[Rob Borkowski 🧬 @rborkows]

Let’s see what it costs once it gets through the FDA

[Sheel Mohnot @pitdesi]

The Midjourney machine costs <1/10th of an MRI machine and the scans are done in a minute (vs an hour for a whole body MRI).

Should make the scans near-free, easy to do regularly for longitudinal study.

Different use case than an MRI

[Rob Borkowski 🧬 @rborkows]

@dr_alphalyrae I was wondering why all my sessions today were nail-biting over things I do all the time and it turned out I was on auto mode instead of this. Never again!

[Rob Borkowski 🧬 @rborkows]

@Rivian what was the point of going out of my way to get a reservation the moment they went live to get lapped by people showing up a year later?

[Nate Silver @NateSilver538]

FIFA is like literally don't believe your eyes instead trust an organization that thought it was a good idea to hold a World Cup in December in fucking Qatar

[Rob Borkowski 🧬 @rborkows]

This is how I treat my team’s JIRA board now and agile has never felt better.

[Paul Graham @paulg]

LinkedIn was already slop. All that's changed is that it's now AI slop.

[Rob Borkowski 🧬 @rborkows]

@furman I was starting another biofx rust rewrite this week (.9999 concordance and 50x better performance with my first one). Was so excited to get Fable to work on it but…

[Rob Borkowski 🧬 @rborkows]

Idea: don’t brag about your model’s capabilities in biology and then be surprised by everyone in biology trying it out and getting pissed. How is this reaction a surprise?

[Nathan C. Frey @nc_frey]

I know this is frustrating. As we said at launch, Fable blocks bio requests entirely for now and reroutes them to Opus 4.8. We made this tradeoff in order to get the model out safely and quickly while we work to refine the classifiers. It is absolutely our goal to enable the whole bio community to use our most powerful models, with appropriately scoped protections in place. We’re working towards this as fast as possible.

[Alexey Strygin @strygah]

New Fable benchmarks from @claudeai

[Rob Borkowski 🧬 @rborkows]

@JBlethrow @agingroy I asked it to review a tech doc on a VCF ingestion pipeline and it crashed out. Absurd

[Rob Borkowski 🧬 @rborkows]

@pbrody Wish I could! Everything I’m working on now is biology related and it’s refusing to play ball on even the most mundane stuff.

[Rob Borkowski 🧬 @rborkows]

@dagarfield @cremieuxrecueil Crashed out on me when I asked it to review a tech spec for a VCF ingestion pipeline update. Tons of excitement for this inside Natera, real buzzkill seeing it’s effectively useless for all our biofx workloads.

[Rob Borkowski 🧬 @rborkows]

@DoorDash_Help I can’t get through your help flow - I get stuck here with this spinner indefinitely.

[Rob Borkowski 🧬 @rborkows]

@StuartBlitz @girdley https://t.co/bMjBSEZ6ms

[Rob Borkowski 🧬 @rborkows]

@trashh_dev Decent pulls so far! Opened 10 with the kids yesterday and got 2 Ex and 2 IRs

[Rob Borkowski 🧬 @rborkows]

@ptr What’s going in??

[Rob Borkowski 🧬 @rborkows]

Just wrapping up porting a major biofx tool from Perl to Rust with LLMs. Worth it (a few months as a side project) but the complexity of DNA splicing made them cry on multiple occasions, even with the right answer to reference.

[ThePrimeagen @ThePrimeagen]

I think the zig to rust port with an LLM is one of the more ideal uses of an LLM. I assume it would excel at this for its literally the purpose of an LLM.

[Rob Borkowski 🧬 @rborkows]

@dacarez0ne_ I went to High School around then/there. Had some friends that were twins and I kid you not one was a Red Sox fan the other Yankees.