Rishi Dhingra

to iterate is human, to recurse divine. McGill tennis/med-tech | Stanford nutrition. Tennis & padel. You can outsource your thinking but not your understanding.

[Rishi Dhingra @rishirajdhingra]

21 years on tour. 21 years with Wilson. Still #BEL21VE.

Tribute thread to ALL his racquets since 1998 (oldest to newest) that got him here, filtered by:

1.Titles won
2.SLAMS won

@rogerfederer @WilsonTennis
#Federer #GOAT #wilson

[Rishi Dhingra @rishirajdhingra]

@josemorgado Similar to his cincy committment.
Hope he recovers for USO

[Rishi Dhingra @rishirajdhingra]

@Dshoopy0 @bryan_johnson My bad, thanks

[Rishi Dhingra @rishirajdhingra]

@TheTennisLetter word.

[Rishi Dhingra @rishirajdhingra]

@TheFigen_ bros gotta eat.

[Rishi Dhingra @rishirajdhingra]

@ExxAlerts you learn something new everyday ✅

[Rishi Dhingra @rishirajdhingra]

@jamesdouma 100%

[Chamath Palihapitiya @chamath]

The AI Singularity

The argument goes like this:

1. Humans build an AGI.
2. The AGI becomes good at AI research.
3. It designs a smarter AI.
4. That smarter AI designs an even smarter AI.
5. The cycle repeats faster and faster.

Looking at the results and capabilities from the various labs over the past few weeks I would say we are firmly in this loop now.

The next 18months will be wild.

Recursive self improvement will dramatically increase capability very quickly from here.

Marginal costs of all models will go to ~$0.

[Rishi Dhingra @rishirajdhingra]

@espn epic achievement.

[Massimo @Rainmaker1973]

Psilocybin made human cells live 50% longer.

A new study has uncovered surprising anti-aging potential in psilocin—the active metabolite produced when the body breaks down psilocybin, the psychoactive compound found in magic mushrooms.

In laboratory experiments, researchers exposed two human cell lines (skin fibroblasts and fetal lung fibroblasts) to a 100 μM concentration of psilocin. The results were striking: lung cells took 57% longer to reach replicative senescence (the point at which cells permanently stop dividing and accumulate damage), while skin fibroblasts extended their replicative lifespan by 51%.

These findings suggest psilocin may slow fundamental cellular aging processes, possibly by lowering oxidative stress, enhancing DNA-repair pathways, supporting mitochondrial health, or dampening chronic inflammation—mechanisms that overlap with those targeted by leading experimental longevity drugs.

The benefits extended beyond cell culture. In aged female mice (19 months old at the start, equivalent to approximately 60–65 human years), a single monthly dose of psilocybin dramatically improved outcomes. After 10 months of treatment, 80% of the psilocybin-treated animals remained alive, compared with only 50% of untreated controls. Treated mice also displayed markedly fewer visible signs of aging, including reduced fur loss and graying.

This research marks the first direct demonstration that psilocybin/psilocin can influence biological aging itself, rather than solely producing psychological effects. The authors emphasize that the study used relatively conservative dosing and are now advocating for follow-up work with higher or more frequent administration, detailed assessments of immune, metabolic, and cognitive function, and investigations into whether the extended lifespan corresponds to genuine improvements in healthspan and quality of life.

["Psilocybin treatment extends cellular lifespan and improves survival of aged mice." npj Aging, 2025]

[National Cancer Institute @theNCI]

Early research suggests that sildenafil, the erectile dysfunction drug commonly known as Viagra, may help stop cancer from spreading, not through its well-known effects on blood flow, but by disrupting how tumor cells manage cholesterol.

Read more: https://t.co/frmD2Gg2B1

[Rishi Dhingra @rishirajdhingra]

@TheTennisLetter @gerebit0 Hair looking good too

[David Sinclair @davidasinclair]

The best longevity drug available today is exercise and building muscle 💪

[Rishi Dhingra @rishirajdhingra]

Two numbers predict how long you stay independent:

VO₂max. Muscle mass.

Neither improves because you tracked it.
Measure less. Train more.

[Rishi Dhingra @rishirajdhingra]

@elonmusk Omg that Economist lady you interviewed with is gonna skip a heart beat now 😂

[Rishi Dhingra @rishirajdhingra]

@Hitchslap1 Exactly. And when you have the time and money to experiment with, why not

[Rishi Dhingra @rishirajdhingra]

@bryan_johnson Its the right move.

[Rishi Dhingra @rishirajdhingra]

@Djoko_UTD Boys gangsta. Love it

[Rishi Dhingra @rishirajdhingra]

@sabirim_ at least the rhino has a legit excuse for listening to his partner

[José Morgado @josemorgado]

Washington ATP 500 2nd round, tomorrow: