๐ฏ #IgAN therapy is moving upstream to B-cell biology
BAFF/APRIL blockade targets survival signals driving IgA Nephrology
#Telitacicept adds to the precision-treatment era in IgA nephropathy
๐ https://t.co/5yqveFZo4s
@NDTsocial#Nephrology
Infection Risk Mitigation with Complement Inhibitors in Kidney Disease
Delighted to share our latest work, now online in NDT, the official journal of the @ERAkidney
๐ Mathilde Berghmans, Francois Seghers, @AKronbichler@smirioglu
https://t.co/hmExpZ6y7X
Oh boy. Target trial emulation does one thing well: it forces the retrospective data researcher (I know a few) to produce a point estimate that will have the same mechanistic interpretation as would be generated by a RCT. It does not address confounding in any special way, and any suggestion otherwise is laughable.
Had a similar case of DILI from Augmentin with AKI-D in setting of extremely high Tbili that we attributed to cholemic nephropathy
We did PLEX in our case as well with concurrent improvement in bili and renal function
We did not do a bx but had bili stained casts on urine micro
1/A new study by Shi et al. (Ann Emerg Med 2026) questions the current AHA blood pressure recommendations for intracerebral hemorrhage.
https://t.co/9Bzhcs2KA5
Which species have the highest VO2max and what separates elite human athletes from antelope, huskies, bats, and hummingbirds?
The answer: geometry & the cube-square law! A fun chance to combine two of my favorite topics into one: exercise & comparative physiology!
1/
again for the people in the back:
urinary tract infection is an EXCEEDINGLY rare cause of nosocomial fever or sepsis.
most such โcasesโ are probably misdiagnoses.
cystitis happens, for sure, but isolated cystitis doesnโt cause fever or sepsis.
@kidney_boy@witchdrkochi@ebtapper may just be genes affecting hemoglobin biology (and thus messing with the lab), not actually diabetes/hyperglycemia/insulin resis per se
On World Hypertension Dayโฆshiny new tool in our toolkit to benefit our patientsโฆ.Baxfendy approved in the US as the first and only aldosterone synthase inhibitor treatment for adults with hypertension https://t.co/ORFchtJn7V