Robert Blassberg

Stem cell biologist interested in cell & gene therapy, genome engineering, gene regulation. Principal Scientist @RevvityInc. @briscoejames lab @TheCrick alumnus

[Robert Blassberg @robertblassberg]

I'm at #ISSCR2024 this week with an update on the work we have been doing @RevvityInc applying the Pin-point #BaseEditing platform to engineer #hypoimmune #iPSC

Looking forward to discussing today at 5:45PM - Poster 235 in the Clinical Applications track

[Robert Blassberg @robertblassberg]

@MaxYunLab @Dev_Cell @HannahWalters30 @sumeetpalsingh8 @DcGenomeCenter @andreaberbau @GiovaPasqui @danilexn @CRTDpress @mpicbg Congratulations Max!

[Robert Blassberg @robertblassberg]

@AMartinezArias Perhaps not so strange when you consider that all parties are filling patents for the creation of synthetic human embryos- the fight to establish priority has implications far beyond academic kudos

[Robert Blassberg @robertblassberg]

@JorgeLazaroF @t_rayon @CellStemCell Nice work Jorge!

[Robert Blassberg @robertblassberg]

Great talk from @nmoris this morning at #ISSCR2023 . Clearly set out the value of both simple and complex pluripotent stem cell derived embryo models. Intriguing data showing maturation of germ cell precursors in 'gastruloids'.

[Robert Blassberg @robertblassberg]

A major milestone reached today on our mission to democratise the therapeutic application of base editing - Revvity and AstraZeneca enter a non-exclusive licencing agreement to apply the Pin-point platform to the creation of cell therapies.

https://t.co/S5hCIYuXt4

[Robert Blassberg @robertblassberg]

Today Horizon Discovery was rebranded as part of PerkinElmer Life Sciences and Diagnostics as Revvity. Exciting times ahead.

https://t.co/Gnz6PrNaf9

[Robert Blassberg @robertblassberg]

@GunesTaylor Yes, I took that from your original post and I agree. My comment was more in response to the linked article - I'm skeptical that therapeutic models developed for caregivers will transfer well to animal technicians due to the different ethics of harm applied in each profession.

[Robert Blassberg @robertblassberg]

@AntoineZalc Sorry to hear about the babysitter- maybe more difficult to find than your next hire!

[Robert Blassberg @robertblassberg]

@AntoineZalc I'd take it as a positive that your lab alumni can secure good jobs in industry (not universally the case). Should make your lab more attractive to candidates nervous about getting 'stuck' in academia.

[Robert Blassberg @robertblassberg]

@AMartinezArias @christlet On that note I should say that @SciencyCheese thread really resonated with me- if you're fortunate to find the right job in industry there is genuinely interesting research to engage with, even if some would not consider it Science.

[Robert Blassberg @robertblassberg]

@AMartinezArias @christlet Thanks @AMartinezArias. Genuinely interested if you think there is/was a funding model (other than core funding) that's substantively different to the early rounds of start-up investment

[Robert Blassberg @robertblassberg]

@AMartinezArias @christlet I'd be interested in your perspective of how grant funding of academic labs was less like raising start-up money in days gone by @AMartinezArias

[Robert Blassberg @robertblassberg]

@Rob_Percival_ Unless you can get @GBNEWS to argue that chickens are actually made out of concrete or some other such nonsense it's probably not worth engaging with them mate

[Robert Blassberg @robertblassberg]

@olivier_debora @briscoejames Thanks Debora!

[Robert Blassberg @robertblassberg]

Thanks also to the reviewers and editorial team @NatureCellBio who helped us to improve our @Biorxivpreprint https://t.co/gpEcnOfZCE

[Robert Blassberg @robertblassberg]

Our updated study of how SOX2 levels direct the WNT response of embryonic progenitors is now out! https://t.co/lgGBYgcZia
It was quite a puzzle to unpick – hopefully this thread helps to show why we found it so intriguing.

[Robert Blassberg @robertblassberg]

This was a really enjoyable collaboration with @aka_hpatel @mina_gouti @metzisv @joadelas @briscoejames. I learned a lot from you all during the time we spent working together @TheCrick.