A true giant of molecular biology. When I was a fresh-faced graduate student he very kindly entertained my questions about his latest (and last, it turns out) paper in @ScienceMagazine. He will be missed.
https://t.co/GZ14yiH58z
Robert C.C. Mercer, PhD & Abdullatif Alsulami, PhD Student present their latest research at #PrionADRDConf2024. See agenda: https://t.co/bdfpZXfSMH
In collaboration with @GMostoslavsky at @CReM_Boston, we've uncovered an interesting phenotype in iPSC-derived neurons from carriers of the E200K mutation of PrP.
Do you want to measure #GPCR activity directly, easily and in your favorite cells? We hope this paper will help. Opus magna led by PhD extraordinaire Remi and former powerhouse postdoc Marcin. Free 50 day access
https://t.co/5lrzchkkmk
https://t.co/h4V260qJhl
Creutzfeldt-Jakob Disease (CJD) is a rare, fatal brain disorder within a group of illnesses called prion diseases. The incidence of CJD cases in the U.S. is ~500 new cases/yr. Raise awareness of #CJD by sharing this video! #CureCJD#RareDiseaseDay
@DebMcKprions @IJMS_MDPI Love seeing the C2C12 system in action. I feel it’s not received the attention it deserves. I’ve been using it myself lately, stay tuned!
@BShoichet @zenbrainest@RothLabUNC@GestwickiLab@ShahmoraLab We looked into that, testing the molecules at 10 uM over 24 hrs. Using N2a cells (relative to amiodarone), the induction of phospholipidosis didn’t correlate with anti-prion effects.
Open to ideas on this one…
This is important and interesting!
@BShoichet
@RothLabUNC
https://t.co/y6ud7PIrW3
Sigma receptor ligands are potent anti-prion compounds that act independently of sigma receptor binding
This is important and interesting!
@BShoichet
@RothLabUNC
https://t.co/y6ud7PIrW3
Sigma receptor ligands are potent anti-prion compounds that act independently of sigma receptor binding
Our recent work on SARS-CoV-2 has come out in @Nature. This study identifies spike and nsp6 as major proteins contributing to Omicron’s pathogenicity/attenuation.
https://t.co/VND8OlGfMz
Variant Creutzfeldt–Jakob disease identified in a technician who had cut her thumb while handling brain sections of mice infected with BSE 7.5 years earlier. https://t.co/4sfnqlDnyf