Maria Rohm

Group leader @HelmholtzMunich @helmholtz_diabc @ERC_Research studying metabolism, energy homeostasis, cachexia

[Maria Rohm @RohmMaria]

👏👏👏 Check out this very cool story on a Tumor secreted protein causing cachexia by altering TGF signaling, by my colleague and friend @BerrielDiaz and led by amazing postdoc @JulianoMacha17. Happy I could contribute a tiny bit 💞

[Helmholtz Diabetes Center (HDC) @helmholtz_diabc]

🚨 New publication in Cancer Discovery!

Our study identifies ADAMTSL4 as a previously unknown driver of #CancerCachexia and a promising therapeutic target.

Congratulations to Juliano Machado, Stephan Herzig, Mauricio Berriel Diaz & all collaborators!

🔗https://t.co/8alqN0viye

[Maria Rohm @RohmMaria]

@A_Bonetto_PhD @NatureComms @JRHUOT_PhD Very nice study, great to see it out!

[Henning Wackerhage @HeWaHippo]

Heute in @zeitonline ein Artikel zur @HyperMet Forschungsgruppe. Bimagrumab-Studien bestätigen, dass die Stimulation von Muskelhypertrophie anti-Adipositas und anti-Diabetes-Effekte hat, die fast genauso stark sind wie die, die mit der Abnehmspritze (GLP1-RAs) erreicht werden.

[Nature Metabolism @NatMetabolism]

#Throwback

REVIEW | @BerrielDiaz, @RohmMaria, S Herzig

Cancer cachexia: multilevel metabolic dysfunction

https://t.co/qBnbYXfCFi

[Maria Rohm @RohmMaria]

Really looking forward to this meeting on #cachexia in Vienna!

[Felix C Richter @CleeteRichter]

Now, we plan the first Vi-CaN symposium with leading cachexia researcher joining the discussion including Vickie Baracos @UAlberta, Eduardo Bruera @UTMDAnderson, @RohmMaria @HelmholtzMunich and @realTonyHui @HarvardChanSPH. Sign up today: https://t.co/hRbPsPelnn

[Felix C Richter @CleeteRichter]

Now, we plan the first Vi-CaN symposium with leading cachexia researcher joining the discussion including Vickie Baracos @UAlberta, Eduardo Bruera @UTMDAnderson, @RohmMaria @HelmholtzMunich and @realTonyHui @HarvardChanSPH. Sign up today: https://t.co/hRbPsPelnn

[Maria Rohm @RohmMaria]

@AJKowaltowski Looking forward to it! 😍

[Henning Wackerhage @HeWaHippo]

Join the DGMet & HyperMet Exercise Metabolomics Symposium!

🗓️ 6 Aug 2026 | ⏰ 16:00–18:00 CEST
🎤 Cora Weigert, Dirk Weber & Tim Havers
Topics: exercise metabolomics, N-acetylated amino acids & oral protein tolerance test. Everyone welcome!
🔗 https://t.co/Lhoc9DW1dj

[Maria Rohm @RohmMaria]

😍 We'd love to hear your thoughts. How can we better integrate cachexia into routine cancer care and precision oncology?
@NaturePortfolio @ERC_Research @helmholtz_de @HelmholtzMunich @helmholtz_diabc @DiabResearch @JoseMGa95491291

[Maria Rohm @RohmMaria]

💫 I'm excited to share our new Comment @NatureRevEndo, calling to reframe #cancercachexia from malnutrition to treatable metabolic disease: https://t.co/v8puKO5aVx

[Maria Rohm @RohmMaria]

Emerging evidence shows that cachexia is a systemic metabolic disease - one that deserves earlier recognition, better monitoring and targeted interventions. Reframing cachexia in this way could help improve quality of life, treatment tolerance and, ultimately, patient outcomes.

[Helmholtz Diabetes Center (HDC) @helmholtz_diabc]

🚨 Abstract submission closes TOMORROW!

Don't miss your chance to present your research at the 13th Helmholtz Diabetes Conference in Munich.

📅 September 21–23
➡️ "Diabetes Across the Lifespan"
📌 Flash Talks • Poster Sessions • Awards
🔗 Submit now: https://t.co/bgLCEWAQMH

[Henning Wackerhage @HeWaHippo]

25th HyperMet talk by Roberta Sartori this Thursday 15 h Munich time. Join here: https://t.co/zwFaYkZwmF
Passcode: h2Vp3fi9

[Nature Metabolism @NatMetabolism]

#Throwback

REVIEW | @BerrielDiaz, @RohmMaria, S Herzig

Cancer cachexia: multilevel metabolic dysfunction

https://t.co/qBnbYXgauQ

[Journal of Clinical Investigation @jclinicalinvest]

ICYMI: What drives metabolic dysfunction and body wasting in cancer #cachexia?

https://t.co/PHjO2GthRb
Here, Pauline Morigny @MorignyPauline Maria Rohm @RohmMaria & team @HelmholtzMunich find high circulating ceramides define cancer cachexia in mice and patients. And targeting ceramide synthesis counteracts mitochondrial dysfunction, impaired energy homeostasis, and muscle atrophy in cachectic mice.

The image: In primary hepatocytes, ceramides interfere with mitochondrial branching and junctions, inducing cachexia-like phenotypes.
#Metabolism #Ceramide

[Maria Rohm @RohmMaria]

Thank you for highlighting our study @PerrimonLab @MarcusDGon 🙏

[Journal of Clinical Investigation @jclinicalinvest]

Liver-derived ceramides link metabolism to tissue wasting in cancer cachexia: https://t.co/1YiYwMG1HA

Norbert Perrimon, Kerui Huang @perrimonlab, Marcus D. Goncalves @marcusdgon @nyugrossman provide a Commentary on Morigny et al.: https://t.co/PHjO2GthRb
@MorignyPauline @RohmMaria #Cachexia #Metabolism #Ceramide

[Maria Rohm @RohmMaria]

@girishkaitholil @MorignyPauline @helmholtz_diabc Thank you. We have indeed shown in a previous publication that elevated circulating ceramides can be detected early in cachexia. It can be an early warning sign. Treatment windows will have to be defined in the future

[Maria Rohm @RohmMaria]

Happy to share our latest paper showing that liver-derived #ceramides drive #muscle dysfunction in #cancer #cachexia . Study led by @MorignyPauline at
@helmholtz_diabc

[Pauline Morigny @MorignyPauline]

I hope you’ll enjoy reading it !
Link to the paper below 👇
https://t.co/qXNbmIRot9
Associated comment 👇
https://t.co/Zvffbha6uo

[Maria Rohm @RohmMaria]

@MorignyPauline @HelmholtzMunich @helmholtz_diabc You are amazing! This beautiful paper is evidence of your creativity, perseverance and scientific rigor. Success is the tip of an iceberg made of hard work, collaboration and trust in the process. Honor to have worked with you @MorignyPauline 🙏❤️