Marcus Goncalves

MD/PhD Endocrinologist Scientist. Cancer metabolism, cachexia, insulin, PI3K, diabetes, obesity. GI Villi lover. Metabolic Consulting. NYJ/NYY/NYCFC/NYK fan.

[Marcus Goncalves @MarcusDGon]

New publication from our group: what happens inside human endometrial tumors during a ketogenic diet?

We analyzed paired tumor biopsies before and after a very low-carbohydrate intervention in women with endometrial cancer 🧵

[Marcus Goncalves @MarcusDGon]

Interesting concept

[Cell Metabolism @Cell_Metabolism]

Mitochondrial lactate venting limits oxidative stress https://t.co/7tkkGNcxzz

[NYU Langone Health Endocrinology Clinical Research @nyuendocrine]

Congratulations to Priya Jaisinghani @doctorjny on becoming President of the Tri-State Obesity Society (TriOS)! Your leadership, dedication to obesity medicine, and commitment to advancing cardio renal metabolic health make you an outstanding choice to guide the organization

[The New York Times @nytimes]

Breaking News: New York City reversed its ban on a Knicks watch party outside of Madison Square Garden ahead of Game 1 of the NBA finals. https://t.co/cxMoruTN7K

[Marcus Goncalves @MarcusDGon]

Looks like specific force, the force a muscle or muscle fiber can generate per cross-sectional area, goes up with semaglutide. What are we treating again?

[Daniel J Drucker @DanielJDrucker]

New from Professor Blau, inhibition of the gerozyme 15-PGDH inhibition promotes muscle repair and strength recovery during GLP-1 receptor agonist-induced weight loss https://t.co/yfaYwoOCOr

[Marcus Goncalves @MarcusDGon]

@MWeintraubMD @EricTopol No way you’re getting #gainz with that. 😆

[Marcus Goncalves @MarcusDGon]

Thank you for the kind words and for championing health and fitness every day. I am grateful to be part of a community that encourages fitness, resilience, and personal growth. HYROX was a great challenge, and I could not have done it without the support of family, friends, and my NYU Langone colleagues.

[Marcus Goncalves @MarcusDGon]

Finished my first Hyrox! Learned a lot for next time. Congrats to all who competed. @nyulangone #HyroxNYC

[nature @Nature]

Catalogue entries for more than 100 antibodies sold by the research services and supply company Thermo Fisher Scientific contain images that have apparently been manipulated, according to a pair of science sleuths.

https://t.co/5rUUgxceoE

[Neil Vasan @NeilVasan]

A new dawn in the treatment of pancreas cancer with daraxonrasib - looking forward to patients getting expanded access immediately and regulatory approval! https://t.co/9XE7Ic1mrh @ASCO @FDAOncology @PanCAN @Perlmutter_CC

[Marcus Goncalves @MarcusDGon]

HYROX weekend! @nyulangone @Elizabeth_Comen
https://t.co/nJ7ThW8Vzi

[THA RAP PILOT 🌍 @therappilot]

#NYULOUNGE JAVITZ CENTER (HYROX) EVENT [VIP]

I MADE $300 TO DO NOTHING YESTERDAY NO CAP I HAD AMAZING DAY

[Marcus Goncalves @MarcusDGon]

Hepatic SEC16B regulates lipid homeostasis by coordinating VLDL secretion and lipid droplet expansion https://t.co/16Ojcpn2hW

[ASCI @the_asci]

Liver-derived ceramides link metabolism to tissue wasting in cancer cachexia: https://t.co/NWOszrZM3c

ASCI member Norbert Perrimon, Kerui Huang @perrimonlab, Marcus D. Goncalves @marcusdgon @nyugrossman provide a Commentary on Morigny et al.: https://t.co/eEatY5M7AZ
@MorignyPauline @RohmMaria
#Cachexia #Metabolism #Ceramide

[John P. Leonard, MD @JohnPLeonardMD]

Excited to get started at #ASCO26 with @Perlmutter_CC @nyulangone activities!

[Daniel J Drucker @DanielJDrucker]

Preclinical studies support combined MC3R/MC4R agonism as a promising approach for next-generation obesity therapeutics #weightloss https://t.co/VnukGvd1DX

[Farooqi Lab @Farooqi_Lab]

In a paper just published in @sciencemagazine, we teamed up with @teichlab to construct the most detailed atlas to date of hormone production and action in humans at cellular resolution. (1/8)

Link: https://t.co/5iPOCq9yfu

[Marcus Goncalves @MarcusDGon]

@Seashellfamily Excellent points. Endometrial cancer sits at the intersection of obesity, insulin resistance, sarcopenia, and altered metabolism. Our study was really designed to ask a narrower question: can a short-term dietary intervention measurably reshape human tumor biology?

[Marcus Goncalves @MarcusDGon]

New publication from our group: what happens inside human endometrial tumors during a ketogenic diet?

We analyzed paired tumor biopsies before and after a very low-carbohydrate intervention in women with endometrial cancer 🧵

[Marcus Goncalves @MarcusDGon]

The early access version of our article is now available online:

https://t.co/W514Tkix4n

[Marcus Goncalves @MarcusDGon]

Extremely grateful to @TheMarkFdn, @theNCI (#DCTD, #PTGB), and the Manoogian Simone Foundation for their strong support of this work. Thank you to @NatureComms for supporting rigorous, hypothesis-driven studies at the intersection of diet, metabolism, and cancer.