Cells are filled with toxic stuff that damages healthy proteins. Is that garbage just left to rot on the curb? No way! Ubiquitin ligases have evolved to recognize chemical damage and clean it up! https://t.co/VKPnOX4ySJ
Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in @NatureBiotech for the story & ways to improve HDR. https://t.co/03GokR65LA With @karasuerman1 & @J_Maciejowski
Metabolic regulation of the hallmarks of stem cell biology by Jackson (@__btjackson) and Finley (@lydfinley)
https://t.co/4x43KGGvRA
Collection highlight from @CellStemCell
I thought my 2 year old was going through a sleep regression at 5 am, but no, he just wanted to let me know that our lab's newest work with @SohrabShah and led by Minsoo Kim was finally online @NatureGenet https://t.co/nj0ZPCbRMH
Pleased to have played a role in showing that transient delivery of a 53BP1 inhibitor peptide improves genome editing outcomes. Thanks to Porteus Lab @StanfordPeds & @ron_baik for leading this! @NatureComms
https://t.co/3Vr1ttgB2i
Do cells care if their mitochondrial DNA is broken? Yes! Excited to share my PhD work showing that a fraction of cells with breaks in their mtDNA recover healthy mitochondria using the integrated stress response.
Delighted to share my research group's latest study, published today @Nature 👉https://t.co/C3BF2Wnyw9 where we trace the life histories of blood cancer development in patients @sangerinstitute@SCICambridge@Cambridge_Uni
In the latest installment in their Night Science series, @ItaiYanai and @MartinJLercher discuss improvisation in generating scientific ideas, and benefits of talking things through with a trusted person to develop those ideas. With bonus Herbie Hancock https://t.co/Q82Hb7O2Zj