Simon Anders

Bioinformatics/Biostatistics Researcher
@[email protected]

[Constantin Ahlmann-Eltze (@const-ae.bsky.social) @const_ae]

Great thread by Anshul, one of the pioneers of deep learning for biology, summarizing our preprint!

[Constantin Ahlmann-Eltze (@const-ae.bsky.social) @const_ae]

This is the result of my brief postdoc with @s_anders_m in the last 6 months and grew out of an intriguing reviewer comment for the LEMUR paper with @wolfgangkhuber.

[Constantin Ahlmann-Eltze (@const-ae.bsky.social) @const_ae]

There's a lot of excitement about foundation models and their ability to learn biology 🧬💻

But current tools for perturbation prediction perform worse than simple linear models! We need more careful benchmarking to make progress.

https://t.co/lTJM7ghk2r

[Simon Anders @s_anders_m]

New preprint from our group:

[Constantin Ahlmann-Eltze (@const-ae.bsky.social) @const_ae]

There's a lot of excitement about foundation models and their ability to learn biology 🧬💻

But current tools for perturbation prediction perform worse than simple linear models! We need more careful benchmarking to make progress.

https://t.co/lTJM7ghk2r

[Martin-Villalba Lab @molneurolab]

🎉 Excited to share our latest study in @nature, showing that DNA🧬 #methylation is key to stemness in the adult #brain: https://t.co/UkZDm4NbdN
A collaboration with @s_anders_m, driven by @LPMKremer and @SCerrizuela. #epigenetics #neuroscience #singlecell. Pre-print summary 🧵👇

[Nature Methods @naturemethods]

And read the Research Briefing here:
https://t.co/5OHRFjQGhN

[Nature Methods @naturemethods]

.@LPMKremer, @molneurolab, @s_anders_m and colleagues introduce a data processing approach along with an easy-to-use software tool MethSCAn for scBS-seq data analysis.

https://t.co/WUcW1EBtDo

[Martin-Villalba Lab @molneurolab]

We're so excited to share our latest work “Identification of astrocyte-driven pseudolineages reveals clinical stratification and therapeutic targets in #Glioblastoma” spearheaded by @OghuzhanKaya on the wet & @LCForst on the dry lab as a preprint @Biorxiv https://t.co/r4od0M6d5D

[Nirmalya Kajuri @Kaju_Nut]

Physicist Suvrat Raju shared this letter he sent to an editor of Nature Communications, declining to referee for them.

[Retraction Watch @RetractionWatch]

“Is Science Self-Correcting? Evidence from 5 Recent Papers on the Effect of Replications on Citations.”
https://t.co/SlI21fEaBk

[Samuel Corless @sam_corless]

Thanks chromatin community! We’ve been digging around in your repetitive DNA (>40,000 ChIP-seq samples) and have discovered a totally unexpected role for BRD4 and JQ1 at centromeres. Very happy to share our preprint. https://t.co/9P1NVWObqt

[Simon Anders @s_anders_m]

PhD and postdoc postions for computational biologists, in the labs of @s_anders_m (me) and @molneurolab (A. Martin-Villalba): Single-cell omics methods in neurobiology. https://t.co/feVSULZTd9

[Simon Anders @s_anders_m]

Life science postdoc positions in Heidelberg:
https://t.co/PhYNBAgFPP

[Martin-Villalba Lab @molneurolab]

@LPMKremer presenting our latest study on epigenetic features of adult neural stem cells at #TCESRC22 on Sicily 🌅, organized by @BrunetLab and @giacomo_cavalli.

[Simon Anders @s_anders_m]

Proud to present this work by @LPMKremer, @SCerrizuela et al. from @molneurolab and our group:

[Martin-Villalba Lab @molneurolab]

We're excited to share our latest preprint where we use #singlecell #multiomics to show that stemness is encoded in the methylome of neural #stemcells (NSC) in the adult #brain 🐁🧠
#epigenetics #neuroscience #biorxiv_neursci
👉https://t.co/2DDNfRQjas
🧵1/9

[Felix Frauhammer @FelixFrauhammer]

cellpypes - cell type pipes for R. Annotate scRNAseq data manually with simple rules:

[Dan Goodman @neuralreckoning]

The current system of journals and peer review is not serving science. I have therefore resigned from all editorial roles and will no longer do pre-publication peer review. I explain why in this article and in the thread below. Please consider joining me.

https://t.co/to0MOUJbID

[Simon Anders @s_anders_m]

@mikelove @slavov_n @MorseCell https://t.co/7znm7mLdEB

[Simon Anders @s_anders_m]

Just started using @TrostNils's R package for plotting 3D scatter points (and more). It's very convenient, powerful and useful.

[Nils Trost @TrostNils]

babyplots - my tool for interactive 3D plots - is now available at https://t.co/qQUOtzFOJJ! Available as a #JavaScript library, an #RStats package, a #PowerPoint add-in and as in interactive creator. Check out some examples: https://t.co/3vPek8suok