Sanjay Chandriani

Curious dad, friend, scientist

[Trace Neuroscience @TraceNeuro]

Today, we're excited to announce we have initiated the global clinical development program for TRCN-1023, an investigational antisense oligonucleotide designed to restore UNC13A protein function for the treatment of #ALS. CEO @ercgrn shares insight below. https://t.co/ESpPgs9bsE

[Trace Neuroscience @TraceNeuro]

1 in 400 people around the world will be diagnosed w/ #ALS in their lifetime. Meet Trace - on a mission to expand the promise of genomic medicine for those w/ neurodegenerative diseases, re-establishing healthy communication between nerves & muscle cells. https://t.co/UdCt0R5upR

[Sanjay Chandriani @sanjayofSF]

https://t.co/vcdFxZA1fS

[Sanjay Chandriani @sanjayofSF]

@MauriceOnTW Thank you! Agree, the number dosed must certainly be larger now.

I’m especially curious how many individuals have been intrathecally dosed with AAVs. Perhaps this reference breaks it out. 🤞

[Sanjay Chandriani @sanjayofSF]

@MauriceOnTW Thanks. Any idea what reference #4 is, relating to that stat?

[Wyatt Clark @wtclark]

I'm excited to announce our most recent publication analyzing the genotype-phenotype relationship in Metachromatic Leukodystrophy (MLD).

https://t.co/5MIZHG3V1l

[Sanjay Chandriani @sanjayofSF]

The Swimmers https://t.co/D09VwsxNTx — a remarkably moving film that captures the desperation, heartbreak, loss, love, luck, and triumph of Syrian refugees

[Sanjay Chandriani @sanjayofSF]

Sign up for Post Prod! https://t.co/A36xJ927IN

[Sanjay Chandriani @sanjayofSF]

@DrJenGunter Ginger and peanuts

[Sanjay Chandriani @sanjayofSF]

@SolidEvidence @PeacockFlu Surveilling #2 to find variants too

[Sanjay Chandriani @sanjayofSF]

@Angry_Staffer What are the next steps in J6 investigation (whether or not TFG complies with subpoena)?

[Sanjay Chandriani @sanjayofSF]

That's my little sis:
The Philadelphia Department of Public Health announces the appointment of Dr. Kinnari Chandriani to the position of Director, Division of Chronic Disease and Injury Prevention. @PHLPublicHealth https://t.co/GbQXi5stBU

[Eric Green @ercgrn]

Camzyos approval a milestone for HCM patients and exemplar for translating human genetics -> medicines. How can we apply this to more diseases? A few insights:

[David Morris @wdmorrisjr]

Parents have to choose their battles.

8 fights worth picking with your kids:

[Joe Neguse @JoeNeguse]

RT if you support my legislation to ban members of Congress from selling and trading stocks.

[Sanjay Chandriani @sanjayofSF]

The (wrong) train’s crew members, however, were awesome — they identified another train we could intercept in Stamford and called the crew of that train to arrange our transfer. @amtrak customer service phone operators could use a lesson from the crew on train #148.
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[Sanjay Chandriani @sanjayofSF]

Unbeknownst to us, our @amtrak train was posted to the wrong track out of NY Penn station. Only after the train started to move did we realize we were on the wrong train. The official @amtrak response was totally unhelpful and unsympathetic.
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[Lily Chiu-Watson @sflily]

@Bob_Wachter Do you have data on how the virus is impacting younger children who aren't vaccinated, both in infection rate but also severity of symptoms? Reading a lot of worrying comments in local parent groups.

[Sanjay Chandriani @sanjayofSF]

Happy to see this work published! While the project didn't end in quite the way we wanted, we learned some interesting glycosphingolipid biology along the way.

[Michael Babcock @MCBabcock]

Excited to share our study in which we evaluate CGT inhibition to reduce GalCers and sulfatides for the treatment of Krabbe disease and MLD. #BioMarin #WUSTL <https://t.co/6461gINhO0>
A thread...
1/17

[Michael Babcock @MCBabcock]

Excited to share our study in which we evaluate CGT inhibition to reduce GalCers and sulfatides for the treatment of Krabbe disease and MLD. #BioMarin #WUSTL <https://t.co/6461gINhO0>
A thread...
1/17