Sathi Wijeyesinghe

Pediatrician scientist | PGY-2 @BCM_pediatrics | MD/PhD from @UMNMSTP and @Masopust_Vezys lab | former postbac @NIH VRC | Terp alum @UofMaryland

[Sakeen Kashem @sakeen_k]

Through sex-inclusive research, we find that meningeal regulatory T cells suppress pain sensitivity under the control of ovarian hormones.

https://t.co/bQMvechGp7

by @EloraMidavaine, at @UCSF, in @ScienceMagazine.

[Michael Lin, MD PhD 🧬 @michaelzlin]

Our NIH grant to discover coronavirus antiviral meds was terminated today.

With this grant, we had developed a better SARSCoV2 inhibitor than Paxlovid, and we recently discovered an improved drug that looks better than Pfizer's own second-generation inhibitor.

[Michael G. Constantinides @Immuno_Mike]

Hear from a talented lineup of immunologists next Wednesday, Sept 18 featuring @zurisullivan, @alexwellsies, @DjenetBousbaine, @ValeriaMReyes, @CicaCanesso, @ScientistBecs, @Liwen_Deng811, & @NZanluqui.

Register: https://t.co/hsdYAY6N0r

[lalit beura @Lalit_Beura1]

Our paper describing in vitro resident memory T cell differentiation in an epithelial organoid model is out at @CellReports https://t.co/7OtHK1LdWo. If you are excited about T cells and reproductive mucosa, we are looking for postdocs-https://t.co/JfegqlS0V2

[Noah Veis Gavil, MD, PhD @Noah_V_Gavil]

Excited to share our perspective on resident memory T cells in solid tumors!!Huge thanks to @ImmunityCP and @Jodi___G. Amazing figures and artwork from @KatarinaECheng and support from the whole @Masopust_Vezys team.
https://t.co/iAsbjUqXdK

[Nicholas Jarjour @NNJarjourPhD]

Delighted to share our new work @Jamequistlab @CFI_UMN on cytokine regulation of homeostatic memory CD8 T cells

https://t.co/NO6j3gi1Va

tl;dr homeostatic circulating and resident memory CD8 T cells are resilient to loss of IL-7Rα (surprise!)

Please RT

Thread follows

[Roland Ruscher @RolandRuscher]

We are seeking 1-2 talented immunology students to join our team in the tropical and picturesque region of North Queensland, where summers are endless and sunshine is abundant.

[Sathi Wijeyesinghe @Sathi_W]

Great postdoc opportunity with @BeuraLab. #AAI2024

[J. Michael Stolley @stolley_michael]

Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses https://t.co/uPDHThyuds

[Elizabeth Thompson @E_A_Thompson]

The Thompson lab is officially live! Excited to announce that I recently accepted a faculty position @JohnsHopkinsMMI studying immunometabolic regulation of vaccine responses. Kicking off the new lab with my first purchase, obviously a @CytekBio flow cytometer!

[Craig Wilen @WilenLab]

Very excited to share our paper led by @madisonstrine Intestinal tuft cell immune privilege enables norovirus persistence | Science Immunology https://t.co/YkmXxCqLlB 1/n

[bioRxiv Immunology @biorxiv_immuno]

CD39 is expressed on functional effector and tissue resident memory CD8+ T cells https://t.co/uratcXzOmT #biorxiv_immuno

[Sanjay Srivatsan @SRsrivatsan]

Thrilled to announce the opening of the Srivatsan Lab (https://t.co/mUPc2wHm0X) at the @fredhutch. The lab will be building new sequencing technologies to understand how our cells and bodies form over the course of development.

[E. John Wherry @EJohnWherry]

Michael is the godfather of viral pathogenesis and the reason so many labs have been able to use LCMV (and other viruses) for fundamental discoveries. He was an inspiration and giant in the field. I will be forever grateful to the advice he gave me early in my career. RIP MBAO

[Donna Farber @DonnaFarber3]

Our study on human T cell memory formation during infancy and childhood revealing progressive maturation of tissue resident subsets in mucosal sites is online—thanks to @tconnors22, @_shivaliv and great collaborators @AYatesGroup, @psimslab @bruskolab.
https://t.co/p0BPhLowBI

[Noah Veis Gavil, MD, PhD @Noah_V_Gavil]

Very excited to share our work in @SciImmunology on the migration properties of CD8+ tumor-infiltrating lymphocytes (TILs)! Using 🐭 models and parabiosis, we uncovered unique features of tumor-resident T cells. Spoiler 🚨tumor ≠ healthy tissue. https://t.co/iMVpMDsYPu 1/7

[Pam Rosato @PCRosato1]

check out our paper from my time as a postdoc in @Masopust_Vezys lab! cellular and humoral immunity working together🤝! Resident memory T cells induce rapid (within hrs) vascular permeability in the female reproductive tract, enabling infiltration of neutralizing antibodies 1/5

[Masopust Vezys Lab @Masopust_Vezys]

Authored by Andrew G. Soerens et al, we show that #Tcells are capable of proliferating in response to iterative stimulation for over 10yrs! And produce enough progeny to occupy a volume 30,000x the Earth's volume! @Nature https://t.co/jPfmX2Ilrq

[Iain Clark @icclarker]

Very excited to share our work on HIV, out this week in @Nature. We sort and RNA-seq infected cells solely based on the detection of provirus DNA. Infected CD4 T cells have unique signatures that help to explain HIV persistence in vivo. https://t.co/WC4tiwLzaB