Simone Park

CRI Fellow @WherryLab @Penn 🇺🇸 | previously @LMackayLab 🇦🇺 | @ForbesUnder30 '22 | T cells in infection, cancer and everywhere in between 👩‍🔬🌜

[Simone Park @simpak]

Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8+ TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 https://t.co/wiKVvR4Ldz

[Jane Yinghui Huang @jane__huang]

Excited to share my graduate work from the @EJohnWherry lab on the molecular mechanisms locking in the differentiation fate of exhausted CD8 T cells (Tex), published earlier this month in @SciImmuno. Main findings below!
https://t.co/2HM8ZAsP5b

[Simone Park @simpak]

@NNJarjourPhD @ImmunityCP @Jamequistlab congratulations!! 👏👏😀 looking forward to reading it 🙂

[Mackay Lab @LMackayLab]

Our latest study, led by @susanna_c_, shows CD47 × PD-L1 bispecific antibodies enhance tumor-resident CD8+ T cell responses, boosting anti-tumor immunity. Grateful to partner with @PfizerOncMed to advance cancer research! 🔬
@TheDohertyInst

https://t.co/GDk8fh9A7X

[Mackay Lab @LMackayLab]

1/ 🚨 Hot off the press! 🚨Our new paper, led by @ObersAndreas & @maxevrard, is now live in @ImmunityCP! 🧬 Curious how CD8+ tissue-resident memory T cells (TRM) adopt their fate in different organs? Let’s dive in! 🧵👇
https://t.co/vcgpgMgBcZ

[E. John Wherry @EJohnWherry]

Very happy to share this new work on LAG3 and PD1. Has been a long road to (begin to) sort out how LAG3 functions in CD8 T cell exhaustion. Great work by Shin Ngiow and super collaboration (and 2 other great papers) with @Vignali_Lab and Dario Vignali https://t.co/My8QIEDJ83

[Simone Park @simpak]

and also excited today to see @divijmathew paper from the lab online now in @ScienceMagazine , a mammoth effort exploring how JAK inhibition modulates checkpoint immunotherapy responses! congratulations Divij!!! https://t.co/OymDn0FbjI

[Simone Park @simpak]

so excited to see this story from the amazing @ScientistBecs and @SunLab_Official out this week! super cool data on how dietary restriction can modulate NK cell function and cancer immunity, massive congratulations to my 🇦🇺 sci-sister Bec! 🙌💫🍾 you are awesome!

[Dr Becs @ScientistBecs]

Thrilled to have this story out online @ImmunityCP!! Together with @SunLab_Official, we highlight how dietary fasting improves NK cell anti-tumor immunity and examine the tissue-specific processes that drive these improved responses 🧵https://t.co/QpyLoMqHoH

[Simone Park @simpak]

@susanna_c_ @LMackayLab yay I am so excited!!! congratulations 🥰🥰 you are amazing!

[Simone Park @simpak]

@yannoudesbois @nhmrc congratulations Yannick!!! so happy to see you get this fellowship! so very well deserved after years of hard work 🙌 excited to see you continue to succeed!

[Simone Park @simpak]

@jenewu1 @ErrantScience 😇

[Simone Park @simpak]

congratulations Emma, Thomas and co. on a really cool study on how CD4 T cells control melanoma! excellent to see this work out in print 🙌🥳

[Emma Grace Bawden @egbawden]

Excited to share our research that describes a variety of mechanisms that CD4+ T cells can employ to target melanoma!

[Simone Park @simpak]

thank you for featuring our study on the Doherty Podcast this week @TheDohertyInst ! was great to talk science 🤓🧬👩‍🔬 follow the link below to listen!!

[Doherty Institute @TheDohertyInst]

📣New podcast episode has dropped! 'Autoimmune skin conditions could be treated by targeting T cells' with @simpak
🎧Find us wherever you listen to your podcasts or via our website: https://t.co/FXOTr4mZrP
@UniMelbMDHS @TheRMH @LMackayLab

[Mackay Lab @LMackayLab]

🌟Excited to share our latest work on how functionally distinct skin TRM utilise different pathways to establish residency, published today in @ScienceMagazine! A true labour of love by BFF @simpak and @susanna_c_! 👩‍🔬 @TheDohertyInst @UniMelb @UniMelbMDHS https://t.co/3m3tNsKqUe

[Simone Park @simpak]

@alexwellsies @BelkaidLab @Nick_Collins11 @SeongJiHan @LMackayLab thank you for all your hard work on this project Alex! couldn't have done it without you!!

[Simone Park @simpak]

thank you also to @theheraldsun https://t.co/Nh9Cv9jTOK and @RNBreakfast https://t.co/hw4ZlCLYHT for spotlighting our work yesterday! 🌟🫶

[Simone Park @simpak]

🙌 @susanna_c_ explaining the implications of our research to @7NewsMelbourne yesterday!

[7NEWS Melbourne @7NewsMelbourne]

Melbourne researchers have made breakthrough discoveries that may help those suffering from skin conditions such as psoriasis. They found new molecules that control disease-causing immune cells in the skin and can be targeted without impacting the barrier that fights off cancer. To discuss, @Rebecca7Maddern spoke with Dr @susanna_c_ from @TheDohertyInst. https://t.co/rJRxhsrlTQ #7NEWS

[Simone Park @simpak]

And last but not least: to @LMackayLab herself -- for pitching me this project when I was bored of measuring tumors, all your support, and for taking this science all the way to the finish line with me. We finally made it! 💫🏆

[Simone Park @simpak]

Are all skin TRM cells created equal? Beyond excited to share our new paper in @ScienceMagazine, where we show diverse CD8+ TRM use distinct molecular pathways to develop and persist in skin, which we can target to fine-tune the skin-immune landscape🧵👇🏻 https://t.co/wiKVvR4Ldz

[Simone Park @simpak]

Top of the list on my thank-you's is the one and only brilliant @susanna_c_- not everyone gets to experience the happiness of sharing a co-first author paper with their best friend, and I feel incredibly lucky to do it with you 🌟🌟