Olivia Swanson

PhD candidate @scrippsresearch 🏳️‍🌈 🧪 #proteindesign #HIVvaccine

[Olivia Swanson @swansolive]

@AzoiteiLab @scrippsresearch Thanks to @TheDHVI for inviting me to talk about the work I'm doing @scrippsresearch to bring ML for protein design to my first scientific passion, making an HIV vaccine!

[miro astore @miroastore]

That's a wrap! The results of the first #cryoEM heterogeneity challenge are up on biorxiv!
https://t.co/5mmJOSHjs1

[Florian Krammer @florian_krammer]

Have you heard of H15? That's a rare avian influenza subtype. @dishabhavsar from my lab and @andrenicoleon from @WardLab1 looked into mAb-H15 structure complexes, antibody responses and antigenic drift.

https://t.co/c0fOPKKN9C

[Gabriele Corso @GabriCorso]

🚀 Excited to release a major update to the Boltz-1 model: Boltz-1x!

Boltz-1x introduces inference-time steering for much higher physical quality, CUDA kernels for faster, more memory-efficient inference and training, and more! 🔥🧵

[rcsb pdb 💉🧬💻🔬💊🌱🧠🦠 @buildmodels]

Many thanks to all of the RCSB PDB depositors, users, and funding agencies that make this project possible
https://t.co/KfKOYtohir

[Science Immunology @SciImmunology]

Repeated #HIV immunizations in rabbits and rhesus macaques can induce anti-idiotypic #antibodies that target anti-HIV antibodies generated by previous immunizations. @WardLab1 @SharidanBrown @scrippsresearch

Read more in Science #Immunology: https://t.co/decqQddh1i

[Priyamvada Acharya @PriyamvadaA_Lab]

Graduate student Ellie Zhang's cryo-EM structure, beautifully rendered by @swansolive made the cover of Science Translational Medicine. @dukebiochem @TheDHVI @DukeMedSchool @DukeU @AzoiteiLab

[Mihai Azoitei @AzoiteiLab]

Our latest paper was just published in @ScienceTM and highlighted on the cover! 🔬🧪🧬

Congrats to first authors Olivia Swanson (@swansolive) and Ellie Zhang 🥳🥳

Read our paper --> [https://t.co/CotwoLixfX]

[Olivia Swanson @swansolive]

@Cat_0321 Thank you, Caitlin!! So grateful for your help with this!

[Scripps Research @scrippsresearch]

Sai Sundar Rajan Raghavan, PhD, and the Ward Lab at Scripps Research, with collaborators, uncovered how antibodies neutralize the malaria parasite. They identified a critical weak spot in the PfEMP1 protein, offering hope for improved malaria vaccines. https://t.co/vpuz12mEl0

[Monica L. Fernández-Quintero @moonii1020]

AlphaFold2+MD simulations = powerful insights into protein conformational ensembles, but can it capture all experimental structural variations? Great collaborative effort!! @Structure_CP @RRiccabona @OPIGlets @scrippsresearch @DTUtweet #compchem https://t.co/RttQqRD1T7

[Lucas Arnoldt @Lucas_Arnoldt]

Thrilled to share our @NatureBiotech paper “Multistate and functional protein design using RoseTTAFold sequence space diffusion” https://t.co/1Fzfpm9s8v.

[Christopher Barnes, Ph.D. @cobarnes27]

Excited and deeply honored to receive the inaugural @BiophysicalSoc Early Independent Career Award!!

So grateful for this recognition, my collaborators, mentors, and most importantly, the @BarnesLab1 team who make it all happen!! This award is truly ours!!! 🙌🏾🫶🏾🍾

[Lander Lab @LanderLab]

Some thoughts on the current state of single particle cryo-EM map/model validation. (TLDR: preferred orientation remains a big problem, ❤️ Q-scores. There's been progress, but there's still more to do. ) https://t.co/E3jcBOyeKA

[PHD Comics @PHDcomics]

Should you ask a question during seminar?

[Science Magazine @ScienceMagazine]

A new @SciImmunology study in adult rhesus macaques describes GT1.1, an immunogen that can activate B cells to produce broadly neutralizing #antibodies against the #HIV CD40-binding site.

Learn more: https://t.co/2XjTE0IQ5e

[Oxford Protein Informatics Group (OPIG) @OPIGlets]

Our Observed T cell receptor Space (OTS) database manuscript has just been published in @CellReports. Includes an analysis of natural paired TCR characteristics and a paired, full-length TCR language model.
https://t.co/sJvRuX56hg

[Lander Lab @LanderLab]

We always thought nucleotide state strictly defined AAA+ conformation, but Jeff Mindrebo's work on mito LONP1 suggests more is at play - substrate interactions also drive protein translocation! Revisiting & rethinking the hand-over-hand mechanism: https://t.co/sUtO4VVbI1

[Martin Pacesa @MartinPacesa]

Today in @Nature we present the results of our exploration of the soluble protein universe and the design of functional soluble membrane proteins with @CasperGoverde @GoldbachNico @befcorreia 1/6

https://t.co/Dakeh8Hyw7

[Monica L. Fernández-Quintero @moonii1020]

Thanks so much to the organisers for this fantastic and inspiring meeting and for the opportunity to present our work!!! @airr_community

[Johannes R. Loeffler @Joe_r_loeffler]

Check out CosolvKit, great work from @bruciaf1! 🚀 Customize your cosolvent systems like never before, opening new avenues in protein characterization and exploration. @Forlilab https://t.co/IlXF7BXQtF #MolecularDynamics #CosolvKit #compchem #drugdesign