Michael He, Ph.D., BPharm (Hons)

Study #lymphoma, #epigenetics, #protac, #immune @PMcancercentre🇨🇦 | Founder @UHNPostdocs | Delegate @OICRRisingStars | Alum @PeterMacCC🇦🇺

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

Targeting epigenetic disruptions in cancer holds promise. Our latest paper in @LeukemiaJnl reveals a novel viral mimicry-interferon mechanism enhancing HDAC3 inhibition in GNAS knockout lymphoma. Proud to lead this challenging project with an amazing team!
https://t.co/aIhVPK2DWy

[Mark Dawson @MAF_Dawson]

We are looking for a talented postdoctoral bioinformatician ⁦@TheDawsonLab⁩ to work with us on single cell multiomics incorporating lineage tracing and spatial technologies- we specifically want someone curious, fearless with a licence to innovate!! https://t.co/gBpTDjb3kI

[Brian Liau @brian_b_liau]

Today in @Nature we share our back-to-back stories with @nzhenguw revealing chemical-genetic convergence between a molecular glue & E3 ligase cancer mutations. 1/6

[UHN Research @UHN_Research]

UHN is proud to be ranked #1 on the list of Canada’s Top 40 Research Hospitals from @R_Infosource for the 14th year in a row!

Thanks to our incredible research community for their continued dedication to #HealthDiscovery, #care & #education!

🔗https://t.co/2RMZhfFife

[Brad Wouters 🇨🇦 @bradwouters]

It takes two to think. Science is a contact sport and one of the reasons why trends in remote work risk scientific progress. Get together - inspire each other.

[Roman Sarott @RomanSarott]

Can we turn the activity of oncogenic kinases against cancer itself?
In my postdoc work @Stanford, new in @sciencemagazine, we show exactly that.
https://t.co/PZjQxvab7z
#ScienceResearch #InducedProximity @Stanford_ChEMH @StanfordCancer @snsf_ch @StanfordMed

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

@RomanSarott @Stanford @ScienceMagazine @Stanford_ChEMH @StanfordCancer @snsf_ch @StanfordMed Amazing work! Congratulations 🎉 🎉

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

I know I must read this masterpiece when I see @MAF_Dawson!
Very happy to see a comprehensive review on the hallmarks of cancer - an epigenetic perspective. Thank you to all the authors.

[Elizabeth McKenna @ElizSMcKenna]

🥁Out today in the October issue of @CD_AACR: ⭐️The Epigenetic Hallmarks of Cancer⭐️ - by @ManelEsteller, @MAF_Dawson, @CKadoch, Feyruz Rassool, Peter Jones, and Steve Baylin https://t.co/Yv48EXBxz5

[Michael Green, PhD @GreenLymphoLab]

Transcriptional/epigenetic chemical inducers of proximity (TCIPs) are an innovative new class of therapeutics that are set to impact lymphoma and other malignancies. Here @RomanSarott, @saigourisankar describe a CDK9 "catch and release" MOA for a new TCIP.
https://t.co/R6D1PU50KQ

[UHN Research @UHN_Research]

As #BloodCancerAwarenessMonth wraps up, we want to congratulate @PMResearch_UHN’s Dr. Robert Kridel @rkridel for publishing three new studies on #lymphoma.

Learn about his team’s dedication to advancing cancer research:
📽️https://t.co/QJmz95lu3o

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

Excited to kick off the fight against #lymphoma with a first score! Honored to work with Dr. Kridel and a great team for these achievements. As Michael Jordan said, 'Talent wins games, but teamwork and intelligence wins championships.' Here’s to more victories in cancer research!

[UHN Research @UHN_Research]

As #BloodCancerAwarenessMonth wraps up, we want to congratulate @PMResearch_UHN’s Dr. Robert Kridel @rkridel for publishing three new studies on #lymphoma.

Read about his team’s dedication to advancing cancer research using genetic analysis.
🔗https://t.co/tCui8kRJ7x @UHN

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

As Chair of the Program Committee for the 1st UHN Postdoc Symposium last year, I know how much effort goes into these events. Great job to the current team on the 2nd! Highly recommend all UHN postdocs join to get inspired and connect. Register now!

[UHN Postdoc Association (UHNPA) @UHNPostdocs]

🚨 Two-week countdown to our 2nd Annual UHN Postdoc Symposium!

🗓️September 18, 2024
📍Room 2-014, Toronto Rehab Institute

Join us to meet the distinguished panelists and explore success beyond a PhD.
Free for UHN postdocs, students, PIs, and staff!

[hansenhe @hansenhe7]

In vivo CRISPR screen of Epigenetic regulators identity therapeutic targets that rely on tumor microenvironment - our recent work is out at Nature Genetics https://t.co/ccRdwdkS8R
Great teamwork @SoundTsao @DanielSchramek @decarvalho_lab @brooks_lab @kuraoncology and many others

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

@levy0803 Thanks Lei! Nice to discuss research with you!

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

Targeting epigenetic disruptions in cancer holds promise. Our latest paper in @LeukemiaJnl reveals a novel viral mimicry-interferon mechanism enhancing HDAC3 inhibition in GNAS knockout lymphoma. Proud to lead this challenging project with an amazing team!
https://t.co/aIhVPK2DWy

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

How does mimicking a viral infection in cancer cells boost epigenetic therapy and anti-tumor immunity? 🧬

Check out our latest blog on targeting HDAC3 in lymphoma! 💡

👉 Read more https://t.co/H7j4k34W26

#CancerResearch #Epigenetics #Lymphoma #HDAC3 #ViralMimicry #Oncology

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

Targeting epigenetic disruptions in cancer holds promise. Our latest paper in @LeukemiaJnl reveals a novel viral mimicry-interferon mechanism enhancing HDAC3 inhibition in GNAS knockout lymphoma. Proud to lead this challenging project with an amazing team!
https://t.co/aIhVPK2DWy

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

@StanInScience @LeukemiaJnl Thanks Stan!

[Andrew M. Evens, DO, MBA, MSc @DrAEvens]

👏👏 Super kudos to @pmcancercentre @rkridel for this outstanding translational work in follicular #lymphoma.

From 713 tumor tissue samples (eg, E4402, E2408 & GALLIUM), 5 genetic subtypes discovered and a/w clinicopath findings & pt outcomes.

👉👉 SEE: https://t.co/xJ1BrUCSSB

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

A special thank you to my advisor @rkridel, mentor @hansenhe7, and all collaborators @YufengXiaoUF @WenxiXu @brooks_lab! Deeply grateful to Prof. Mark Dawson @MAF_Dawson, Prof. Steven Stacker, and @thePMCF @PMResearch_UHN @UHN_Research @uhntrainees @UHNPostdocs for their support!

[Michael He, Ph.D., BPharm (Hons) @themichaelhe]

Thank you Dr. Patrizia Mondello @pattymondello for highlighting our work and the wonderful perspective! https://t.co/Pq6lsODFG2