@stkirsch .
Observational pharmacovigilance (active and passive) cannot detect rare, delayed, or dispersed chronic signals.
Without long-term randomized control groups,
subtle or time-scattered risks blend into background noise and unmeasurable confounding factors.
@GFUniteMankind@denisrancourt 2008 former health minister Seehofer open admits
For 30 years up until this very hour-structural changes in the healthcare system have been prevented by resistance from lobby groups
I can only describe to you that this is the case, and that this is how it works-very effectively
@IanCopeland5@MakisMedicine The dead end:
The unknown HVE blocks every observational study from the path to causal inference regarding All Cause Mortality. At best, they allow estimates under heroic assumptions.
The way out, adequately powered RCTs with ACM as endpoint does not exist.
Game over.
@IanCopeland5 .
You confuse a chart with causality.
It proves nothing.
The HVE is unknowable, no observational design can fix this.
Only a randomized ACM-endpoint trial would.
None exists.
@muzikguy1@IanCopeland5 .
Feel free to clap
it only proves you also know nothing about science.
Google Hernรกn and HVE maybe you'll stop laughing if you actually understand what you will find.
@Humanspective .
A government that uncritically endorses and advances such measures has effectively placed itself under a political conservatorship,
proving it lacks the mental capacity for independent governance
@briandavidearp .
A placebo is not a withholding of care, but the sole zero point.
Without a live zero point, a trial fails to isolate a true causal effect.
Exploiting human subjects for an experiment that measures mere noise for lack of an anchor is unethical self-deception.
@Kristof_Poland 14 years ago, our IT security consisted of one person; today, it consists of a manager, seven employees, external consulting firms, two days of training per employee per yearโ a lot expensive software to manage security, instead of building secure operating systems and software.
@HHSGov@POTUS@SecKennedy@NIH .
At least better than what we have now.
- Transparent public access to anonymized raw data
- Elimination of liability exemption
@IanCopeland5@grok Or in short:
Henry Rollins' "Liar" (1994) โ A Structural Description of Modern AI
The core elements of the lyrics describe exactly the systemic problem of modern large language models:
https://t.co/91UnUwbTb7?