铜锣饼

Psychiatry Neurology Depression Cognition Multiple sclerosis Neuroimaging Multimodal Runner

[NEJM @NEJM]

Clinical Implications of Basic Research: The Legacy of Orexin (Hypocretin) Research in Narcolepsy and Beyond https://t.co/0xRDHDS7Qw

#Neurology #SleepMedicine

[铜锣饼 @tongluobing]

@RosaCortese5 Huge congrats, Rosa! So happy for you! Fantastic work and such an exciting publication! 🎉💫

[Nat Rev Neurology @NatRevNeurol]

New online! Use of MRI in neuromyelitis optica spectrum disorder and myelin oligodendrocyte glycoprotein antibody-associated disease — MAGNIMS consensus recommendations https://t.co/2YkWgnCdJY

[Psychiatric Times @PsychTimes]

Pramipexole was associated with improvement in anhedonia and apathy, and with increased physical activity in patients with mood disorders, in a placebo-controlled trial that measured both behavioral and neurophysiologic change. https://t.co/QwlGrTY3B2

[Eric Topol @EricTopol]

🆕 @ScienceMagazine
Each person's aging trajectory is unique, a dynamic interplay at the molecular level, influenced by genetic, lifestyle and environmental factors (such as PFAS).
Findings from a longitudinal study of 335 women (148 identical twins) over 8 years w/ gene expression and metabolomics
https://t.co/izf1HUvEe7

[Joshua Rosenblat, MD, MSc, FRCPC @JD_Rosenblat]

See our RCT published today @JAMAPsych

Serial Ketamine Infusions for Treatment-Resistant Bipolar Depression (TRBD)

In TRBD, adjunctive IV ketamine was well tolerated and associated with significant antidepressant effects.

@UofTPsych @KBI_UHN @UHN

https://t.co/bZLqN3VNHJ

[Eric Topol @EricTopol]

"can eventually help us better decode and improve life"
Some big thinking here on building and integrating multi-scale models @NatureMedicine
by @segal_eran @dasongle @ericxing @WeizmannScience @genbioai @CarnegieMellon

[Eric Topol @EricTopol]

Brain drain surgery
Does it work to simulate the function of glymphatics and help prevent or treat Alzheimer's disease?
Feature @Nature by @ElieDolgin
https://t.co/2jGTgtU31a

[The BMJ @bmj_latest]

The Patient Health Questionnaire (PHQ)-9, PHQ-8, and PHQ-2 are the most commonly used mental health outcome measures in clinical practice.

New BMJ Research assesses the minimal important difference of the PHQ-9, PHQ-8, or PHQ-2
https://t.co/g39lew6EXy

[Fenng @Fenng]

可惜这篇文章还需要付费墙才可以阅读，削弱了影响力：

经过一年的调查，团队取得了 16 个国家在 2025 年两个季度办理赴瑞典签证的申请数据，并采访了 24 名 VFS 现任及前任员工。我们试图还原全球最大签证外包商 ——VFS Global—— 如何利用全球流动的不平等，通过高压销售、附加服务和签证制度中的权力失衡，从申请者身上持续获利，并逐渐成长为一个难以约束的跨国巨头。

[JAMA Psychiatry @JAMAPsych]

This narrative review suggests mental disorders are statistical clusters of biopsychosocial properties, not sharply defined categories, mirroring concepts in species classification and supporting dimensional #MentalHealth frameworks. https://t.co/9VfN5cStLG

[Science Magazine @ScienceMagazine]

As we sleep, our bodies may be quiet and largely immobile—but our brains are highly active.

A special issue summarized recent insights into the basic mechanisms underlying sleep and the many functions our brains perform during it.

Learn more on #WorldSleepDay: https://t.co/lNkpyRpxak

[Brain @Brain1878]

Kollenburg et al. review the molecular mechanisms and regional activity patterns underlying conditions including migraine, cluster headache, and paroxysmal hemicrania, integrating basic and clinical perspectives. https://t.co/qs2ibqv30y

[The Lancet @TheLancet]

Migraine affects 1·2 billion people worldwide.

In the last few years, several new migraine-specific preventive treatments have become available, improving patient quality of life.

Find out more in a new Review in @TheLancetNeuro 👉 https://t.co/UTDkVx9w8B

[Science Magazine @ScienceMagazine]

A new Science study in mice identifies a novel non-synaptic signaling mechanism between the brain and peripheral sensory system important for migraine. The results suggest potential pharmacological targets for treating the painful disorder.

Learn more: https://t.co/JLjjyEEzM8

[铜锣饼 @tongluobing]

循此苦旅，以达天际

[铜锣饼 @tongluobing]

祛晦迎新

[Sai Zhang @saizhang0]

Someone is running jobs on 128 GPU nodes (~1000 A100) during holidays. Is this a normal PhD life?

[Mr.VE折太郎 @monkeyalien]

@ilufie 最后他们果然训练出了一个酒量超好、push厂家和下级博士很厉害、每年固定时间打招呼润滑基金关系、一有指南微信群就挂名字、全国开会讲ppt拿讲课费、门诊通常由带组副高代劳、每一千多年上一次临床、亲自读过的只有自夸公关稿的那种三甲主任级AI医生……（也挺好的

[Sixth Tone @SixthTone]

Inspired by Disney’s “Snow White” in 1937, the Wan brothers created the first Chinese animated feature film — still a timeless classic today — during the hardship of World War II.

Read more: https://t.co/QTcu8jjsOs