Saket Jain

A philosopher at heart, a product manager by day, and a basketball fan for life.

[Saket Jain @toSaket]

@david_perell 💙

[Saket Jain @toSaket]

@JuliusYRitter Looking forward to a Eli Lilly 🤝 Dandelion collab. Great read.

[Saket Jain @toSaket]

🫡

[John Collison @collision]

We're launching Intercept, a new philanthropic initiative to fight respiratory viruses like colds and flus. https://t.co/ETkOVI9Xgh

[Saket Jain @toSaket]

@brianluidog I donated blood to Red Cross religiously every 8-12 weeks for years. Struggled with fatigue and it took me a long time to figure out my ferritin had dropped. I agree with the sentiment.

[Rob Perez @WorldWideWob]

Once in a lifetime talent.

[Saket Jain @toSaket]

@maxmarchione

[Saket Jain @toSaket]

@signulll @sammmdix I value the convenience and conviction of @superpower AI with data from @ouraring, over my PCP.

[Saket Jain @toSaket]

@maxmarchione @signulll Love @superpower integrated with @ouraring for this

[Saket Jain @toSaket]

@liminal_warmth 30k miles on my Tesla, 99% driven by FSD.

[Saket Jain @toSaket]

@CoachDanGo It tracks with Huberman’s sleep stack (glycine, mag threonate, apigenin, l-theanine) coupled with LMNT. Works well for me.

[Saket Jain @toSaket]

@grok @wassupeduardo @nypost @grok what was the US wine revenue in past 3 years? What’s the % change this year?

[Saket Jain @toSaket]

@wolfejosh Beautifully captured 📸 in my home town

[Saket Jain @toSaket]

@punishedfounder What were your top 3 takeaways, things that surprised you? I’ve been looking for a reason to get my DNA tests done.

[Andrej Karpathy @karpathy]

Very interested in what the coming era of highly bespoke software might look like.

Example from this morning - I've become a bit loosy goosy with my cardio recently so I decided to do a more srs, regimented experiment to try to lower my Resting Heart Rate from 50 -> 45, over experiment duration of 8 weeks. The primary way to do this is to aspire to a certain sum total minute goals in Zone 2 cardio and 1 HIIT/week.

1 hour later I vibe coded this super custom dashboard for this very specific experiment that shows me how I'm tracking. Claude had to reverse engineer the Woodway treadmill cloud API to pull raw data, process, filter, debug it and create a web UI frontend to track the experiment. It wasn't a fully smooth experience and I had to notice and ask to fix bugs e.g. it screwed up metric vs. imperial system units and it screwed up on the calendar matching up days to dates etc.

But I still feel like the overall direction is clear:
1) There will never be (and shouldn't be) a specific app on the app store for this kind of thing. I shouldn't have to look for, download and use some kind of a "Cardio experiment tracker", when this thing is ~300 lines of code that an LLM agent will give you in seconds. The idea of an "app store" of a long tail of discrete set of apps you choose from feels somehow wrong and outdated when LLM agents can improvise the app on the spot and just for you.
2) Second, the industry has to reconfigure into a set of services of sensors and actuators with agent native ergonomics. My Woodway treadmill is a sensor - it turns physical state into digital knowledge. It shouldn't maintain some human-readable frontend and my LLM agent shouldn't have to reverse engineer it, it should be an API/CLI easily usable by my agent. I'm a little bit disappointed (and my timelines are correspondingly slower) with how slowly this progression is happening in the industry overall. 99% of products/services still don't have an AI-native CLI yet. 99% of products/services maintain .html/.css docs like I won't immediately look for how to copy paste the whole thing to my agent to get something done. They give you a list of instructions on a webpage to open this or that url and click here or there to do a thing. In 2026. What am I a computer? You do it. Or have my agent do it.

So anyway today I am impressed that this random thing took 1 hour (it would have been ~10 hours 2 years ago). But what excites me more is thinking through how this really should have been 1 minute tops. What has to be in place so that it would be 1 minute? So that I could simply say "Hi can you help me track my cardio over the next 8 weeks", and after a very brief Q&A the app would be up. The AI would already have a lot personal context, it would gather the extra needed data, it would reference and search related skill libraries, and maintain all my little apps/automations.

TLDR the "app store" of a set of discrete apps that you choose from is an increasingly outdated concept all by itself. The future are services of AI-native sensors & actuators orchestrated via LLM glue into highly custom, ephemeral apps. It's just not here yet.

[Saket Jain @toSaket]

@khushkhushkhush @superpower is going for the vertical integration to win this. Hims recently acquired a us-based peptide facility as well https://t.co/1UN0GUPxLM

[Dario Amodei @DarioAmodei]

The Adolescence of Technology: an essay on the risks posed by powerful AI to national security, economies and democracy—and how we can defend against them: https://t.co/0phIiJjrmz

[Saket Jain @toSaket]

@zebird0 I’ve been microdosing 0.5mg every 5th day for over three months. With regular strength training, and high protein intake, I’ve managed to lose 8% in body fat without significant muscle loss (backed by dexa scans). Baseline energy levels are higher. Impulsive behavior is in check

[Saket Jain @toSaket]

@hubermanlab Can peptides like Elamipretide and MOTS-c help restore mitochondrial function?

[Saket Jain @toSaket]

A single 🩸 donation can save lives. Love this initiative by @superpower X @RedCross #BloodFriday

[Saket Jain @toSaket]

Incredible. Thank you for sharing.

[nxthompson @nxthompson]

I've just written about my very intense relationship with my father and how running helped me both connect with him and avoid becoming him.

It's also my first article ever for @TheAtlantic . My dad wrote for the magazine in 1967, and i t seems fitting that the first piece published here from my family in 58 years is about him.
https://t.co/XpfAWImtoc