Trisha Wittkopp

Geneticist, interested in evolution and development. Bluesky: All posts reflect my own views, not those of a university.

[Trisha Wittkopp @twittkopp]

Beautiful images from Erick Bayala (postdoc in the Wittkopp lab) using HCR to visualize expression of multiple mRNAs throughout pupal development help us understand how the temporal and spatial regulation of gene expression determines adult traits (pigmentation, in this case).

[Molecular Instruments @HCRimaging]

#onlywithHCR: Visualizing RNA Expression in Drosophila Pupal Development 🔬

A study on Drosophila by Bayala et al. highlights a novel protocol using HCR™ technology to study RNA expression in the fragile and impermeable tissues of the Drosophila epidermis during pupal development.

@EXBayala and his co-authors describe a method for dissecting tissue and detecting RNA across various stages, including early and late pupal stages, as well as larval imaginal discs.

Powered by HCR™ imaging, this approach allows for the study of dynamic gene expression patterns throughout the pupal development process, overcoming the challenges of tissue fragility and impermeability.

Learn more about the study here: https://t.co/IgTxv99sxG

[Trisha Wittkopp @twittkopp]

@sfiscience @big_data_kane @schmidtsciences Congrats!!!

[Trisha Wittkopp @twittkopp]

@MoSephius What fraction of the audience do you think picked up on it? (And despite the fact it probably should have been, it was never ColdPlay)

[Trisha Wittkopp @twittkopp]

@NKWhiteman @PMB_Berkeley @trnpl @EMBO And I was lucky enough to see it person. She did a great job!

[Trisha Wittkopp @twittkopp]

@Xinjun90 @NIGMS Congratulations!!!

[Trisha Wittkopp @twittkopp]

@LuisZaman Oh my! Totally off mark and uncalled for! (But also happy to help in anyway I can)

[Trisha Wittkopp @twittkopp]

@MeauxJuliette @OfficialSMBE Congratulations 🎉 what wonderful news! I hate to miss the meeting this year.

[Trisha Wittkopp @twittkopp]

@ikadow Congratulations, Ilona!!

[Trisha Wittkopp @twittkopp]

@bdelloid Neurospora with its ordered tetrads?

[Trisha Wittkopp @twittkopp]

@FascinatingPupa @pbeldade @molecology @ellafuente @DDuneau Beautiful work, @ellafuente and @pbeldade! We also saw (with much lower resolution) differences in QTLs among body parts for pigmentation divergence between D. elegans and D. gunungcola: https://t.co/FrYktGoLdL

[Ewan Birney @ewanbirney]

This is a nice review on ancestral recombination graphs (ARGs), the one graph to rule them all for population genetics. We are entering an era where one can conceptualise at least entire population ARGs. https://t.co/4FCKPkAiLz

[Matt Friedman @Friedman_Lab]

Ann Arbor: center of the organismal biology universe in June 2024?

North American Paleontological Convention (June 17-21)🦕🐚🌿

International Congress on the Biology of Fish (June 23-27)🐟🐠🐡

Society for the Study of Amphibians and Reptiles (June 27-30)🦎🐍🐢

[Trisha Wittkopp @twittkopp]

@3Xueying Congratulations!

[Trisha Wittkopp @twittkopp]

@landrychristian Thanks @landrychristian. That means a lot coming from you. Your 2014 paper with Guillaume Diss (https://t.co/NCE5JBC4Lw) was an inspiration. As were conversations with Zachary Lippman from @CSHL following #EMBOPredictEvo

[Trisha Wittkopp @twittkopp]

Our new paper showing that reduction in gene activity is compensated for by up-regulation of a paralog, mediated by TFs regulating both genes #PLOSGenetics: Active compensation for changes in TDH3 expression mediated by direct regulators of TDH3 in Sa ... https://t.co/BbfzDubQI1

[Roberto Márquez @rmp033]

I am looking for *two* postdocs to join my lab at @VT_Biology next summer/fall. We work on the molecular basis of coloration and toxicity in poison-dart frogs. Please RT!!
Job ad: https://t.co/EE5BapOTqi
Application link: https://t.co/4YAOaqx3Tb

[Trisha Wittkopp @twittkopp]

@mbeisen And it was amazing! Thank you still!

[Gideon Bradburd @gbradburd]

Posting on twitter right now feels a little like putting up an informational flyer on the deck of the Titanic, but I'm recruiting PhD students to work on spatial population genetics in my lab at @UMichEEB!

[Trisha Wittkopp @twittkopp]

Are you a PEQG researcher looking for a meeting that combines highly relevant organism specific content & broader topic driven insights? #TAGC24is the perfect conference for you. Submit an abstract by Nov 9: @GeneticsGSA https://t.co/gGhp9sTs9A”

[Genetics Society of America @GeneticsGSA]

Join us for #PEQG24 at #TAGC24! Hear the latest #population, evolutionary & quantitative genetics research plus other organism-specific & topic-driven insights 📊🧬 Reconnect & form new collabs with international scientists. Submit an abstract & register: https://t.co/DH4PJUVOfJ

[Trisha Wittkopp @twittkopp]

Always a favorite meeting!

[Genetics Society of America @GeneticsGSA]

Join us for #Dros24 at #TAGC24! Hear the latest #Drosophila research plus other organism-specific content & broader topic-driven insights 🪰🧬 Reconnect & form new collaborations with scientists from all over the world. Submit an abstract & register: https://t.co/DH4PJUVOfJ