Simple habits for a calm life:
- not checking you phone first thing in the morning
- spending 20 min in the morning doing nothing
- going for long walks without music or podcasts
- eating without watching something
- journaling what’s been on your mind
- sitting in silence with your coffee
- saying no without explaining yourself
- doing things without posting them online
- having a hobby you never plan to monetize
- enjoy ordinary moments without needing them to be productive
- creating something with your hands just because it feels good
- listening to your favorite album from start to finish without doing anything else
- building a life you don’t need to escape from
One of the biggest complaints one hears about Africa is that good reliable data is hard to come by. I disagree; not if you know where to look and read the signs. For example if the leaders of a company go to State House to meet the President and together they announce that in October the company will begin exporting product Y worth $50 million a month and employ 3,500 people, the chance that it will happen is 12.5%. If the President visits the company and the announcement is made on the factory floor with the big man wearing a safety helmet and white lab coat, the chances that it will is 25%. If the company holds a big launch event, invites 50 social media influencers and a leading musician, plus a minister or ambassador to “flag off” the 1st consignment, the chances that it will succeed drop to 5%. If it does nothing, doesn’t invite the President or send out a press release, and only posts a photo of a chubby-cheeked smiling worker which doesn’t give away much on their social media page, put some of your money there. Their chance of success is about 65%.
No incisions. No needles. Just focused sound waves destroying liver tumors from outside the body.
The HOPE4LIVER trial treated 49 liver tumors across 44 patients with histotripsy and was published in Radiology last year. 95% technical success rate. Still a small, single-arm trial with short follow-up, so we don't have long-term survival data yet. But the direction matters.
The part that interests me most is what happens to the immune system after you destroy a tumor this way. When a tumor is destroyed in place, the debris left behind contains cancer antigens. That's the raw material the immune system needs to recognize and hunt down remaining cancer cells throughout the body. I've built my career around this principle. Ablation combined with intratumoral immunotherapy consistently outperforms either approach alone.
The technology will keep evolving. Sound waves, cryoablation, pulsed electric fields. The principle won't change. Destroy the tumor locally, leave the antigens, activate the immune system. That's the future of cancer treatment. Not one tool. The right combination.
“Scientists capture the full ‘brain-cleaning’ process during sleep”
Sleep is crucial for the brain. When a person is in deep sleep, cerebrospinal fluid flows between neurons like waves, clearing metabolic waste and “resetting the system” for thinking and learning the next day. But what happens if you don’t get enough sleep?
Scientists at Boston University in the United States have captured this “cleaning” process. Red represents blood, and blue represents cerebrospinal fluid. After falling asleep, neurons become quiet, and within a few seconds, blood flows out of the head. Then a watery fluid called cerebrospinal fluid (CSF) flows in, washing the brain in rhythmic pulses.
What’s remarkable is that it was previously unknown that blood periodically flows out of the brain in large amounts. Each time this happens, cerebrospinal fluid takes the opportunity to surge in.
Once inside the brain, cerebrospinal fluid clears toxins, such as beta-amyloid, which is linked to Alzheimer’s disease. This cleaning process only occurs during sleep, allowing the brain to feel refreshed upon waking. When awake, cerebrospinal fluid doesn’t get enough opportunity to do this effectively.
Researchers also found a connection between brainwave activity and the cleaning process, meaning brainwaves help drive the movement of these fluids.
So, it’s better to go to bed earlier—don’t stay up too late!
If the “cleaning” doesn’t work well, you might actually get dumber…
@MrBusinge If it’s true that he actually got western education then nah! He didn’t attend class because Morrison’s reasoning is 0
If a manager can micro manage a work place, do you know micro managing power? Doing it to benefit one person at the expense of 48m. Do better Morrison