Muhammad Usama

Resident physician in pathology | Tweets my own | 🇵🇰🇺🇲

[Renal Pathology Society @Renalpathsoc]

Yale Pathology is accepting applications for 1-year combined Renal & GU Pathology fellowship starting July 1, 2027 & 2028. See image below & link for more info. Apply: [email protected]
https://t.co/RycxSsLkg1
#renalpath #GU #fellowship #pathX #pathtwitter

[Andrew Bellizzi 🇺🇦 @IHC_guy]

I just had a WOW moment. I'm doing admin work for @ISIMMweb this afternoon.

From 10/24 through 12/25 we had 1407 people from 84 countries register for one or more webinar.

We'll announce registration for the 2026-7 series this week.

I am truly humbled.

Here's a preview:

[Arkana Laboratories @arkanalabs]

Anti-LRP2 nephropathy is a form of kidney disease primarily affecting the elderly in which progressive renal tubular injury is seen in association with circulating autoantibodies to the tubular brush border protein LRP2 (aka megalin). Histopathologically, it is characterized by IgG immune complexes in the tubular basement membrane. Similar tubular basement membrane deposits can be seen in other diseases such as lupus nephritis and IgG4-related disease. However, TBM staining for LRP2 is unique to cases with anti-LPR2 nephropathy. Normally, LRP2 is restricted to the apical membrane of the proximal tubules. LRP2 staining along the tubular basement membranes is abnormal indicates the presence of anti-LRP2 nephropathy. 

Reference: J Am Soc Nephrol. 2017 Oct 26. [Epub ahead of print] PMID: 29074737

#TeachingPoints #kidneypath #renal #pathology

[Jonathan Zuckerman MD PhD @JZRenalPath]

Fibrillary GN with linear staining potentially mimicking anti-GBM. Mesangial staining + mesangial expansion by silver weak material not typical for anti-GBM. Also only focal crescents. fibrils infiltrating GBM on EM. #renalpath #pathtwitter #nephrology

[Ting Zhao, MD @TingZhaoPathdoc]

Location and diagnosis?

#PathTwitter @MGBpathology

[Ankur Sangoi @slusagar]

#GUpath puzzler time!
adult human, radical nephrectomy performed for renal mass

🤔Dx? 🔬

[Sanjeev Sethi @SethiRenalPath]

Mimic:
IgA Nephropathy can mimic immune complex (IC)-MPGN.

LM: Membranoproliferative (MPGN) pattern
Routine IF: inconclusive
Pronase IF: mesangial IgA 2+
EM: mesangial deposits

Dx: IgA nephropathy M1 E1 S0 T0 C0

Case was labeled primary IC-MPGN

50-yr old with hematuria and proteinuria. Serology negative.

[Muhammad Usama @usamamuhammad07]

Grateful to share that I’ve officially accepted a fellowship in Renal Pathology. 🫘🔬

A subspecialty I’ve grown to love, and a journey I’m very excited to continue. 🌱

[Jonathan Zuckerman MD PhD @JZRenalPath]

Case of bile cast nephropathy in a patient with biliary stricture and acute kidney injury. Many green brown bile casts associated with diffuse tubular injury. Also green/brown cytoplasmic granules in proximal tubules. #renalpath

[Muhammad Usama @usamamuhammad07]

@arkanalabs Chronic, active antibody mediated rejection.

[Muhammad Usama @usamamuhammad07]

@HafizGhani_MD @UTSW_GIpath @GIJamesMD @SuntreaHammer How was it signed out?

[Hafiz A. Ghani @HafizGhani_MD]

Colon biopsy:
GMS highlights the yeast forms, while HHV8 positivity has Kaposi Sarcoma knocking on the door! 🚪👀

Pathology never stops surprising! 🔬

#GIJames #GIPathology #Pathology #Histoplasmosis #HHV8 #UTSW

[Grace Choung, MD 박영이 @grace_choung]

Tertiary lymphoid structures in lupus nephritis are associated with aging and chronic kidney injury - Kidney International Reports https://t.co/H9Mqa8C03x

[Anthony Chang, MD (張賀文) @ChangUCanSpare]

Nephropathologists - provide your feedback on the renal path competency expectations for pathology residents from @TheABPath. Open comments until 8/31/26

https://t.co/5NBOODd9RP

[Muhammad Usama @usamamuhammad07]

@arkanalabs Viral nuclear changes along with interstitial inflammation and tubular atrophy.
Most likely polyoma nephritis.
SV40 for confirmation.

[Anthony Chang, MD (張賀文) @ChangUCanSpare]

Dear nephrologist - do you equate the pathologic finding of acute tubular injury with the clinical term "acute tubular necrosis"?

[Ankur Sangoi @slusagar]

#GUpath prostate cancer is super neurotropic!

👀worshiping this nerve from radical prostatectomy section

#pathart

[Muhammad Usama @usamamuhammad07]

@AranzaPinedo @NMA_Pathology @AAPPHealth @PIMGlatino @MGBpathology @AMWADoctors @ProjectImg Congratulations

[Appl Immunohistochem Mol Morphol Journal @AimmJournal]

🚀 Join us for our Journal Club Live Webinar Series!
📚 Articles #openaccess starting 7/27
👨🏻‍💻 Don't miss this opportunity to explore new research with us! #AIMMjc

🔗 https://t.co/qqjEzE2Tot
🔗 https://t.co/Ty05o9TwoI

Register 👉🏻 https://t.co/eXRc3Cdf6P

[Paola Romagnani @PRomagnani]

Our new study in @JASN_News: Autoantibody specificity matters: anti-nephrin, anti-podocin, and anti-KIRREL1 antibodies define autoimmune podocytopathies with distinct phenotypes, prognosis, and transplant recurrence risk. https://t.co/tGaYIZuyqF